Prothena Corporation plc (PRTA)

NASDAQ: PRTA · Real-Time Price · USD
9.21
-0.10 (-1.07%)
Mar 13, 2026, 4:00 PM EDT - Market closed
Market Cap495.80M -36.7%
Revenue (ttm)9.68M -92.8%
Net Income-244.09M
EPS-4.53
Shares Out 53.83M
PE Ration/a
Forward PE37.34
Dividendn/a
Ex-Dividend Daten/a
Volume584,453
Open9.40
Previous Close9.31
Day's Range9.00 - 9.54
52-Week Range4.32 - 14.34
Beta-0.28
AnalystsBuy
Price Target19.00 (+106.3%)
Earnings DateFeb 19, 2026

About PRTA

Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson’s disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau a... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2012
Employees 67
Stock Exchange NASDAQ
Ticker Symbol PRTA
Full Company Profile

Financial Performance

In 2025, Prothena Corporation's revenue was $9.68 million, a decrease of -92.83% compared to the previous year's $135.16 million. Losses were -$244.09 million, 99.6% more than in 2024.

Financial Statements

Analyst Summary

According to 9 analysts, the average rating for PRTA stock is "Buy." The 12-month stock price target is $19.0, which is an increase of 106.30% from the latest price.

Price Target
$19.0
(106.30% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Prothena Announces Achievement of $50 Million Clinical Milestone Payment from Novo Nordisk Related to Ongoing Phase 3 Clinical Trial for Coramitug (Formerly PRX004) in ATTR Amyloidosis with Cardiomyopathy

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena earned a $50 million milestone from Novo Nordisk related to enrollment in the Phase 3 CLEOPATTRA trial evaluating coramitug for ATTR-CM.

4 days ago - Business Wire

Prothena: A Hold With 2 Late-Stage Programs Underway But With Caution

Prothena Corporation plc is maintained at a Hold rating due to mixed phase 2 data and long timelines for key programs. PRTA's leading assets, prasinezumab (Parkinson's disease) and coramitug (ATTR-CM)...

10 days ago - Seeking Alpha

Prothena Announces up to $100 Million Share Repurchase Plan

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced its Board has authorized a Share Repurchase Plan so it may repurchase up to $100 million of the Company's outstanding shares.

14 days ago - Business Wire

Prothena Corporation plc (PRTA) Q4 2025 Earnings Call Transcript

Prothena Corporation plc (PRTA) Q4 2025 Earnings Call Transcript

22 days ago - Seeking Alpha

Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights.

22 days ago - Business Wire

Prothena to Report Fourth Quarter and Full Year 2025 Financial Results on February 19, 2026

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced that it will report its fourth quarter and full year 2025 financial results on Thursday 2/19/26 with a conference call at 4:30pm ET.

4 weeks ago - Business Wire

Prothena Announces Board of Directors Update

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Corporation plc (NASDAQ:PRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein...

3 months ago - Business Wire

Prothena Announces Poster Presentation on its TDP-43 CYTOPE® Program at Neuroscience 2025

DUBLIN, Ireland--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Announces Poster Presentation on its TDP-43 CYTOPE® Program at Neuroscience 2025.

4 months ago - Business Wire

Prothena Highlights Phase 2 Data for Coramitug (Formerly PRX004) Published in Circulation, Official Journal of AHA

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Phase 2 clinical data for coramitug, a potential first-in-class amyloid depleter antibody, for the treatment of ATTR-CM published in Circulation.

4 months ago - Business Wire

Prothena Reports Third Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena today reported financial results for the third quarter and first nine months of 2025 and provided business highlights.

4 months ago - Business Wire

Prothena to Report Third Quarter 2025 Financial Results on November 6

DUBLIN, Ireland--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena will report its third quarter 2025 financial results on Thursday November 6, 2025, after the close of the U.S. financial markets.

4 months ago - Business Wire

Prothena's Partner Bristol Myers Squibb Obtains Fast Track Designation from the U.S. FDA for BMS-986446 (PRX005), an Anti-MTBR-Tau-Targeting Antibody, for the Treatment of Alzheimer's Disease

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--PRTA announced that BMS communicated that the FDA granted Fast Track Designation to BMS-986446, an anti-tau antibody in P2 for Alzheimer's disease.

5 months ago - Business Wire

Prothena to Participate in the Cantor Fitzgerald Global Healthcare Conference

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Corporation plc (NASDAQ:PRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein...

7 months ago - Business Wire

Prothena Provides Update on PRX012 and Announces Results from the Phase 1 ASCENT Clinical Program

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Provides Update on PRX012 and Announces Results from the Phase 1 ASCENT Clinical Program.

7 months ago - Business Wire

Prothena Announces that Novo Nordisk Will Advance Coramitug (Formerly PRX004) into Phase 3 Development for ATTR Amyloidosis with Cardiomyopathy

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced that Novo Nordisk communicated that they expect to advance coramitug into a Phase 3 program for ATTR-CM in 2025.

7 months ago - Business Wire

Prothena Reports Second Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena today reported financial results for the second quarter and first six months of 2025 and provided business highlights.

7 months ago - Business Wire

Prothena to Report Second Quarter 2025 Financial Results on August 4

DUBLIN--(BUSINESS WIRE)--Prothena today announced that it will report its second quarter and first six months of 2025 financial results on August 4, 2025.

8 months ago - Business Wire

Prothena Announces Corporate Restructuring

DUBLIN--(BUSINESS WIRE)--Prothena announced that the Company has initiated an approximate 63% reduction in its workforce.

9 months ago - Business Wire

Prothena's Partner Roche to Advance Prasinezumab into Phase III Development for Early-Stage Parkinson's Disease

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena announced partner Roche will advance prasinezumab into Phase III development in early-stage Parkinson's disease.

9 months ago - Business Wire

Why Is Prothena Stock Trading Lower On Tuesday?

Prothena Corporation plc PRTA released data from the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with AL amyloidosis on Friday.

10 months ago - Benzinga

Prothena Announces Phase 3 AFFIRM-AL Clinical Trial for Birtamimab in Patients with AL Amyloidosis Did Not Meet Primary Endpoint

DUBLIN--(BUSINESS WIRE)--Prothena today announced the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with AL amyloidosis did not meet its primary endpoint.

10 months ago - Business Wire

Top 3 Health Care Stocks That Are Preparing To Pump This Quarter

The most oversold stocks in the health care sector presents an opportunity to buy into undervalued companies.

Other symbols: RXSTSRPT
11 months ago - Benzinga

Prothena Reports First Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today reported financial results for the first quarter of 2025 and provided business highlights.

11 months ago - Business Wire

Prothena to Report First Quarter 2025 Financial Results on May 8

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today announced that it will report its first quarter 2025 financial results on Thursday, May 8, 2025.

11 months ago - Business Wire

Prothena Corporation plc (PRTA) Q4 2024 Earnings Call Transcript

Prothena Corporation plc (NASDAQ:PRTA) Q4 2024 Earnings Conference Call February 20, 2025 4:30 PM ET Company Participants Mark Johnson - Vice President of Investor Relations Gene Kinney - President a...

1 year ago - Seeking Alpha