Prothena Corporation plc (PRTA)
| Market Cap | 453.82M -17.1% |
| Revenue (ttm) | 54.53M +427.3% |
| Net Income | -43.99M |
| EPS | -0.83 |
| Shares Out | 51.34M |
| PE Ratio | n/a |
| Forward PE | n/a |
| Dividend | n/a |
| Ex-Dividend Date | n/a |
| Volume | 931,618 |
| Open | 8.57 |
| Previous Close | 8.61 |
| Day's Range | 8.50 - 9.31 |
| 52-Week Range | 7.73 - 11.80 |
| Beta | -0.29 |
| Analysts | Hold |
| Price Target | 21.40 (+142.08%) |
| Est. Earnings | Nov 5, 2026 |
About PRTA
Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson’s disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau a... [Read more]
Financial Performance
In 2025, Prothena Corporation's revenue was $9.68 million, a decrease of -92.83% compared to the previous year's $135.16 million. Losses were -$244.09 million, 99.6% more than in 2024.
Financial StatementsAnalyst Summary
According to 6 analysts, the average rating for PRTA stock is "Hold." The 12-month stock price target is $21.4, which is an increase of 142.08% from the latest price.
News
Prothena to Participate in the H.C. Wainwright 28th Annual Global Investment Conference
DUBLIN, Ireland--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena to Participate in the H.C. Wainwright 28th Annual Global Investment Conference.
Prothena Reports Second Quarter 2026 Financial Results and Business Highlights
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena reported financial results for the second quarter and first six months of 2026 and provided business highlights.
Prothena Corporation Earnings release: Q2 2026
Prothena Corporation released its Q2 2026 earnings on August 6, 2026, summarizing the period's financial results.
Prothena Corporation Quarterly report: Q2 2026
Prothena Corporation has published its Q2 2026 quarterly earnings report on August 6, 2026.
Prothena Corporation Slides: Corporate presentation
Prothena Corporation has posted slides in relation to its latest quarterly earnings report, which was published on August 6, 2026.
Prothena to Report Second Quarter 2026 Financial Results on August 6
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena will report its second quarter and first six months of 2026 financial results on August 6, 2026.
Prothena Reports First Quarter 2026 Financial Results and Business Highlights
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena today reported financial results for the first quarter of 2026 and provided business highlights.
Prothena Corporation Earnings release: Q1 2026
Prothena Corporation released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.
Prothena Corporation Quarterly report: Q1 2026
Prothena Corporation has published its Q1 2026 quarterly earnings report on May 7, 2026.
Prothena Corporation Slides: Corporate presentation
Prothena Corporation has posted slides in relation to its latest quarterly earnings report, which was published on May 5, 2026.
Prothena to Report First Quarter 2026 Financial Results on May 7
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced that it will report its first quarter 2026 financial results on Thursday, May 7, 2026, after close of the U.S. financial markets.
Prothena Announces Novo Nordisk Obtains Fast Track Designation from the U.S. FDA for Coramitug (PRX004) in ATTR Amyloidosis with Cardiomyopathy
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announces Novo Nordisk obtains Fast Track Designation from the U.S. FDA for coramitug (PRX004) in ATTR amyloidosis with cardiomyopathy.
Prothena Announces Leadership Team Updates
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena promoting Ms. Kingston to Chief Strategy Officer and Mr. Isaacs to General Counsel and Corporate Secretary. Mr. Malecek is departing in June.
Prothena Corporation Proxy statement: Proxy filing
Prothena Corporation filed a proxy statement on March 27, 2026, providing details for shareholder voting and corporate governance matters.
Prothena Corporation Proxy statement: Proxy filing
Prothena Corporation filed a proxy statement on March 27, 2026, providing details for shareholder voting and corporate governance matters.
Prothena Partners Present Data Supporting Next Generation Treatments for Parkinson's and Alzheimer's Disease at AD/PD™ 2026
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena partners presented clinical data updates for prasinezumab for Parkinson's and BMS-986446 for Alzheimer's disease at AD/PD™ 2026.
Prothena Corporation Transcript: The Citizens Life Sciences Conference 2026
The company highlighted its robust pipeline in neurodegenerative and protein misfolding diseases, with major partnered programs advancing in phase III and significant milestone payments expected this year. CYTOPE technology was showcased as a novel platform for targeting intracellular proteins, with further updates anticipated in 2024.
Prothena Announces Achievement of $50 Million Clinical Milestone Payment from Novo Nordisk Related to Ongoing Phase 3 Clinical Trial for Coramitug (Formerly PRX004) in ATTR Amyloidosis with Cardiomyopathy
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena earned a $50 million milestone from Novo Nordisk related to enrollment in the Phase 3 CLEOPATTRA trial evaluating coramitug for ATTR-CM.
Prothena Corporation Slides: Corporate presentation
Prothena Corporation has posted slides in relation to its latest quarterly earnings report, which was published on March 9, 2026.
Prothena Announces up to $100 Million Share Repurchase Plan
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced its Board has authorized a Share Repurchase Plan so it may repurchase up to $100 million of the Company's outstanding shares.
Prothena Corporation Earnings Call Transcript: Q4 2025
Advanced key partnered programs into phase 3, introduced CYTOPE technology, and maintained a strong cash position. 2025 financials were favorable to guidance, with 2026 outlook projecting lower cash use and potential $105M in milestones.
Prothena Corporation Annual report: Q4 2025
Prothena Corporation has published its Q4 2025 annual report on February 19, 2026.
Prothena Corporation Earnings release: Q4 2025
Prothena Corporation released its Q4 2025 earnings on February 19, 2026, summarizing the period's financial results.
Prothena Corporation Slides: Q4 2025
Prothena Corporation has posted slides in relation to its Q4 2025 quarterly earnings report, which was published on February 19, 2026.
Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights
DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights.