Company Description
Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat solid tumors.
Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; PYX-102, an investigational immunotherapeutic targeting KLRG1, an inhibitory receptor on T cells and NK cells, with potential for use as monotherapy or in combination treatments; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors.
The company is also developing PYX-107, a CD40 agonist with demonstrated anti-cancer activity in patients with several cancer indications, which is in Phase 2 clinical trial for the treatment of tumors, such as soft tissue sarcomas, esophageal and gastroesophageal junction, cancers, and pancreatic ductal adenocarcinoma.
It has an in-license agreement with Pfizer Inc. to develop and commercialize ADC product candidates, including micvotabart pelidotin and PYX-203, and other ADC product candidates directed to the licensed targets; and Biosion USA, Inc. for development, manufacture, and commercialization of PYX-106, an IO product candidate.
Pyxis Oncology, Inc. was incorporated in 2018 and is headquartered in Boston, Massachusetts.
| Country | United States |
| Founded | 2018 |
| IPO Date | Oct 1, 2021 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 56 |
| CEO | Thomas Civik |
Contact Details
Address: 321 Harrison Avenue, 11th Floor, Suite 1 Boston, Massachusetts 02118 United States | |
| Phone | 617 453 3596 |
| Website | pyxisoncology.com |
Stock Details
| Ticker Symbol | PYXS |
| Exchange | NASDAQ |
| Stock Type | Common Stock |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| IPO Price | $16.00 |
| CIK Code | 1782223 |
| CUSIP Number | 747324101 |
| ISIN Number | US7473241013 |
| Employer ID | 83-1160910 |
| SIC Code | 2834 |
Key Executives
| Name | Position |
|---|---|
| Thomas Civik | Interim Chief Executive Officer and Director |
| Dr. Balu N. Balasubramanian Ph.D. | Interim Chief Technology Officer |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Apr 30, 2026 | ARS | Filing |
| Apr 30, 2026 | DEFA14A | Additional definitive proxy soliciting materials and Rule 14(a)(12) material |
| Apr 30, 2026 | DEF 14A | Other definitive proxy statements |
| Apr 30, 2026 | 8-K/A | [Amend] Current report |
| Mar 23, 2026 | S-8 | Securities to be offered to employees in employee benefit plans |
| Mar 23, 2026 | 10-K | Annual Report |
| Mar 23, 2026 | 8-K | Current Report |
| Feb 9, 2026 | SCHEDULE 13G/A | Filing |
| Feb 6, 2026 | 8-K | Current Report |
| Dec 18, 2025 | 8-K | Current Report |