Septerna, Inc. (SEPN)

Septerna Statistics

Total Valuation

Septerna has a market cap or net worth of $513.62 million. The enterprise value is $165.24 million.

Market Cap	513.62M
Enterprise Value	165.24M

Important Dates

The last earnings date was Monday, August 11, 2025, after market close.

Earnings Date	Aug 11, 2025
Ex-Dividend Date	n/a

Share Statistics

Septerna has 44.59 million shares outstanding. The number of shares has increased by 1,313.80% in one year.

Current Share Class	44.59M
Shares Outstanding	44.59M
Shares Change (YoY)	+1,313.80%
Shares Change (QoQ)	+0.52%
Owned by Insiders (%)	3.17%
Owned by Institutions (%)	53.85%
Float	18.20M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	716.06
Forward PS	11.08
PB Ratio	1.38
P/TBV Ratio	1.38
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	227.60
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 22.09, with a Debt / Equity ratio of 0.07.

Current Ratio	22.09
Quick Ratio	21.76
Debt / Equity	0.07
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -32.78% and return on invested capital (ROIC) is -22.37%.

Return on Equity (ROE)	-32.78%
Return on Assets (ROA)	-21.58%
Return on Invested Capital (ROIC)	-22.37%
Return on Capital Employed (ROCE)	-25.53%
Revenue Per Employee	$9,680
Profits Per Employee	-$1.17M
Employee Count	75
Asset Turnover	0.00
Inventory Turnover	n/a

Taxes

Income Tax	-296,000
Effective Tax Rate	n/a

Stock Price Statistics

Beta (5Y)	n/a
52-Week Price Change	n/a
50-Day Moving Average	11.47
200-Day Moving Average	n/a
Relative Strength Index (RSI)	47.25
Average Volume (20 Days)	215,285

Short Selling Information

The latest short interest is 3.17 million, so 7.12% of the outstanding shares have been sold short.

Short Interest	3.17M
Short Previous Month	3.74M
Short % of Shares Out	7.12%
Short % of Float	17.44%
Short Ratio (days to cover)	13.41

Income Statement

In the last 12 months, Septerna had revenue of $726,000 and -$87.51 million in losses. Loss per share was -$2.84.

Revenue	726,000
Gross Profit	726,000
Operating Income	-102.16M
Pretax Income	-9.78M
Net Income	-87.51M
EBITDA	-100.60M
EBIT	-102.16M
Loss Per Share	-$2.84

Balance Sheet

The company has $326.56 million in cash and $24.57 million in debt, giving a net cash position of $354.62 million or $7.95 per share.

Cash & Cash Equivalents	326.56M
Total Debt	24.57M
Net Cash	354.62M
Net Cash Per Share	$7.95
Equity (Book Value)	377.56M
Book Value Per Share	8.47
Working Capital	319.01M

Cash Flow

In the last 12 months, operating cash flow was -$81.40 million and capital expenditures -$1.63 million, giving a free cash flow of -$83.03 million.

Operating Cash Flow	-81.40M
Capital Expenditures	-1.63M
Free Cash Flow	-83.03M
FCF Per Share	-$1.86

Margins

Gross Margin	100.00%
Operating Margin	-14,071.07%
Pretax Margin	-12,093.80%
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

Septerna does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-1,313.80%
Shareholder Yield	-1,313.80%
Earnings Yield	-16.83%
FCF Yield	-15.97%

Analyst Forecast

The average price target for Septerna is $26.75, which is 132.21% higher than the current price. The consensus rating is "Strong Buy".

Price Target	$26.75
Price Target Difference	132.21%
Analyst Consensus	Strong Buy
Analyst Count	5
Revenue Growth Forecast (5Y)	n/a
EPS Growth Forecast (5Y)	n/a

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

Septerna has an Altman Z-Score of 9.14 and a Piotroski F-Score of 2.

Altman Z-Score	9.14
Piotroski F-Score	2