Septerna, Inc. (SEPN)
NASDAQ: SEPN · Real-Time Price · USD
28.50
-1.07 (-3.62%)
Nov 28, 2025, 11:26 AM EST - Market open

Septerna Statistics

Total Valuation

Septerna has a market cap or net worth of $1.28 billion. The enterprise value is $786.52 million.

Market Cap1.28B
Enterprise Value 786.52M

Important Dates

The last earnings date was Monday, November 10, 2025, before market open.

Earnings Date Nov 10, 2025
Ex-Dividend Date n/a

Share Statistics

Septerna has 44.77 million shares outstanding. The number of shares has increased by 1,704.89% in one year.

Current Share Class 44.77M
Shares Outstanding 44.77M
Shares Change (YoY) +1,704.89%
Shares Change (QoQ) +3.25%
Owned by Insiders (%) 3.21%
Owned by Institutions (%) 46.53%
Float 18.75M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 55.33
Forward PS 12.36
PB Ratio 3.40
P/TBV Ratio 3.41
P/FCF Ratio 12.83
P/OCF Ratio 12.70
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 35.68
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF 7.62

Financial Position

The company has a current ratio of 6.53, with a Debt / Equity ratio of 0.06.

Current Ratio 6.53
Quick Ratio 6.46
Debt / Equity 0.06
Debt / EBITDA n/a
Debt / FCF 0.23
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -22.38% and return on invested capital (ROIC) is -19.46%.

Return on Equity (ROE) -22.38%
Return on Assets (ROA) -14.32%
Return on Invested Capital (ROIC) -19.46%
Return on Capital Employed (ROCE) -16.84%
Revenue Per Employee $293,933
Profits Per Employee -$784,120
Employee Count75
Asset Turnover 0.06
Inventory Turnover n/a

Taxes

Income Tax -160,000
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +13.72% in the last 52 weeks.

Beta (5Y) n/a
52-Week Price Change +13.72%
50-Day Moving Average 21.29
200-Day Moving Average 12.44
Relative Strength Index (RSI) 69.14
Average Volume (20 Days) 359,785

Short Selling Information

The latest short interest is 1.92 million, so 4.29% of the outstanding shares have been sold short.

Short Interest 1.92M
Short Previous Month 2.03M
Short % of Shares Out 4.29%
Short % of Float 10.25%
Short Ratio (days to cover) 6.04

Income Statement

In the last 12 months, Septerna had revenue of $22.05 million and -$58.81 million in losses. Loss per share was -$1.43.

Revenue22.05M
Gross Profit 22.05M
Operating Income -89.49M
Pretax Income -58.97M
Net Income -58.81M
EBITDA -87.90M
EBIT -89.49M
Loss Per Share -$1.43
Full Income Statement

Balance Sheet

The company has $474.35 million in cash and $24.11 million in debt, giving a net cash position of $537.45 million or $12.00 per share.

Cash & Cash Equivalents 474.35M
Total Debt 24.11M
Net Cash 537.45M
Net Cash Per Share $12.00
Equity (Book Value) 388.73M
Book Value Per Share 8.71
Working Capital 416.40M
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was $104.22 million and capital expenditures -$1.07 million, giving a free cash flow of $103.15 million.

Operating Cash Flow 104.22M
Capital Expenditures -1.07M
Free Cash Flow 103.15M
FCF Per Share $2.30
Full Cash Flow Statement

Margins

Gross margin is 100.00%, with operating and profit margins of -405.95% and -266.77%.

Gross Margin 100.00%
Operating Margin -405.95%
Pretax Margin -267.49%
Profit Margin -266.77%
EBITDA Margin n/a
EBIT Margin n/a
FCF Margin 467.92%

Dividends & Yields

Septerna does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -1,704.89%
Shareholder Yield -1,704.89%
Earnings Yield -4.44%
FCF Yield 7.79%

Analyst Forecast

The average price target for Septerna is $30.25, which is 6.14% higher than the current price. The consensus rating is "Strong Buy".

Price Target $30.25
Price Target Difference 6.14%
Analyst Consensus Strong Buy
Analyst Count 5
Revenue Growth Forecast (5Y) 95.37%
EPS Growth Forecast (5Y) -19.47%
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

Septerna has an Altman Z-Score of 1.66 and a Piotroski F-Score of 2. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.66
Piotroski F-Score 2