Septerna, Inc. (SEPN)
NASDAQ: SEPN · Real-Time Price · USD
41.86
-6.70 (-13.80%)
At close: Nov 12, 2026, 4:00 PM EST
41.10
-0.76 (-1.82%)
After-hours: Nov 12, 2026, 7:30 PM EST

Septerna Statistics

Total Valuation

Septerna has a market cap or net worth of $1.99 billion. The enterprise value is $1.45 billion.

Market Cap1.99B
Enterprise Value 1.45B

Important Dates

The last earnings date was Monday, November 9, 2026, after market close.

Earnings Date Nov 9, 2026
Ex-Dividend Date n/a

Share Statistics

Septerna has 47.55 million shares outstanding. The number of shares has increased by 9.89% in one year.

Current Share Class 47.55M
Shares Outstanding 47.55M
Shares Change (YoY) +9.89%
Shares Change (QoQ) +4.16%
Owned by Insiders (%) 2.81%
Owned by Institutions (%) 59.82%
Float 27.28M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 20.68
Forward PS 35.15
PB Ratio 4.64
P/TBV Ratio 4.65
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 15.03
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 4.84, with a Debt / Equity ratio of 0.05.

Current Ratio 4.84
Quick Ratio 4.77
Debt / Equity 0.05
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -14.45% and return on invested capital (ROIC) is -10.63%.

Return on Equity (ROE) -14.45%
Return on Assets (ROA) -7.48%
Return on Invested Capital (ROIC) -10.63%
Return on Capital Employed (ROCE) -14.26%
Weighted Average Cost of Capital (WACC) 16.15%
Revenue Per Employee $718,418
Profits Per Employee -$440,291
Employee Count134
Asset Turnover 0.16
Inventory Turnover n/a

Taxes

In the past 12 months, Septerna has paid $5.94 million in taxes.

Income Tax 5.94M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +117.57% in the last 52 weeks. The beta is 2.20, so Septerna's price volatility has been higher than the market average.

Beta (5Y) 2.20
52-Week Price Change +117.57%
50-Day Moving Average 40.35
200-Day Moving Average 33.03
Relative Strength Index (RSI) 46.30
Average Volume (20 Days) 421,986

Short Selling Information

The latest short interest is 3.35 million, so 7.05% of the outstanding shares have been sold short.

Short Interest 3.35M
Short Previous Month 3.52M
Short % of Shares Out 7.05%
Short % of Float 12.29%
Short Ratio (days to cover) 8.65

Income Statement

In the last 12 months, Septerna had revenue of $96.27 million and -$59.00 million in losses. Loss per share was -$1.31.

Revenue96.27M
Gross Profit 96.27M
Operating Income -73.39M
Pretax Income -53.06M
Net Income -59.00M
EBITDA -71.75M
EBIT -73.39M
Loss Per Share -$1.31
Full Income Statement

Balance Sheet

The company has $565.19 million in cash and investments and $21.99 million in debt, with a net cash position of $543.20 million or $11.42 per share.

Cash & Investments 565.19M
Total Debt 21.99M
Net Cash 543.20M
Net Cash Per Share $11.42
Equity (Book Value) 427.93M
Book Value Per Share 9.03
Working Capital 402.49M
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$76.57 million and capital expenditures -$1.02 million, giving a free cash flow of -$77.59 million.

Operating Cash Flow -76.57M
Capital Expenditures -1.02M
Depreciation & Amortization 1.64M
Net Borrowing n/a
Free Cash Flow -77.59M
FCF Per Share -$1.63
Full Cash Flow Statement

Margins

Gross margin is 100.00%, with operating and profit margins of -76.23% and -61.29%.

Gross Margin 100.00%
Operating Margin -76.23%
Pretax Margin -55.11%
Profit Margin -61.29%
EBITDA Margin -74.53%
EBIT Margin -76.23%
FCF Margin n/a

Dividends & Yields

Septerna does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
FCF Payout Ratio n/a
Buyback Yield -9.89%
Shareholder Yield -9.89%
Earnings Yield -3.12%
FCF Yield -3.90%

Analyst Forecast

The average price target for Septerna is $59.22, which is 41.47% higher than the current price. The consensus rating is "Strong Buy".

Price Target $59.22
Price Target Difference 41.47%
Analyst Consensus Strong Buy
Analyst Count 10
Revenue Growth Forecast (3Y) 5.31%
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a
Graham Formula Value n/a
Graham Formula Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

Septerna has an Altman Z-Score of 4.19 and a Piotroski F-Score of 1.

Altman Z-Score 4.19
Piotroski F-Score 1