Septerna, Inc. (SEPN)
NASDAQ: SEPN · Real-Time Price · USD
26.13
+1.14 (4.56%)
At close: Apr 17, 2026, 4:00 PM EDT
26.23
+0.10 (0.39%)
After-hours: Apr 17, 2026, 5:48 PM EDT

Septerna Statistics

Total Valuation

Septerna has a market cap or net worth of $1.17 billion. The enterprise value is $648.37 million.

Market Cap1.17B
Enterprise Value 648.37M

Important Dates

The next estimated earnings date is Thursday, May 14, 2026, before market open.

Earnings Date May 14, 2026
Ex-Dividend Date n/a

Share Statistics

Septerna has 44.91 million shares outstanding. The number of shares has increased by 347.46% in one year.

Current Share Class 44.91M
Shares Outstanding 44.91M
Shares Change (YoY) +347.46%
Shares Change (QoQ) -2.24%
Owned by Insiders (%) 3.20%
Owned by Institutions (%) 57.68%
Float 22.90M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 25.54
Forward PS 13.65
PB Ratio 3.07
P/TBV Ratio 3.07
P/FCF Ratio 10.70
P/OCF Ratio 10.65
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 14.11
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF 5.91

Financial Position

The company has a current ratio of 4.73, with a Debt / Equity ratio of 0.06.

Current Ratio 4.73
Quick Ratio 4.66
Debt / Equity 0.06
Debt / EBITDA n/a
Debt / FCF 0.22
Interest Coverage n/a

Financial Efficiency

Return on equity (ROE) is -12.19% and return on invested capital (ROIC) is -148.17%.

Return on Equity (ROE) -12.19%
Return on Assets (ROA) -9.59%
Return on Invested Capital (ROIC) -148.17%
Return on Capital Employed (ROCE) -15.87%
Weighted Average Cost of Capital (WACC) n/a
Revenue Per Employee $353,469
Profits Per Employee -$375,992
Employee Count130
Asset Turnover 0.09
Inventory Turnover n/a

Taxes

In the past 12 months, Septerna has paid $12,000 in taxes.

Income Tax 12,000
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +336.23% in the last 52 weeks.

Beta (5Y) n/a
52-Week Price Change +336.23%
50-Day Moving Average 26.14
200-Day Moving Average 21.29
Relative Strength Index (RSI) 55.40
Average Volume (20 Days) 286,584

Short Selling Information

The latest short interest is 2.18 million, so 4.85% of the outstanding shares have been sold short.

Short Interest 2.18M
Short Previous Month 2.08M
Short % of Shares Out 4.85%
Short % of Float 9.51%
Short Ratio (days to cover) 7.48

Income Statement

In the last 12 months, Septerna had revenue of $45.95 million and -$48.88 million in losses. Loss per share was -$1.10.

Revenue45.95M
Gross Profit 45.95M
Operating Income -80.80M
Pretax Income -48.87M
Net Income -48.88M
EBITDA -79.19M
EBIT -80.80M
Loss Per Share -$1.10
Full Income Statement

Balance Sheet

The company has $391.09 million in cash and $23.63 million in debt, with a net cash position of $525.03 million or $11.69 per share.

Cash & Cash Equivalents 391.09M
Total Debt 23.63M
Net Cash 525.03M
Net Cash Per Share $11.69
Equity (Book Value) 381.93M
Book Value Per Share 8.52
Working Capital 324.03M
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was $110.19 million and capital expenditures -$518,000, giving a free cash flow of $109.67 million.

Operating Cash Flow 110.19M
Capital Expenditures -518,000
Depreciation & Amortization 1.60M
Net Borrowing n/a
Free Cash Flow 109.67M
FCF Per Share $2.44
Full Cash Flow Statement

Margins

Gross margin is 100.00%, with operating and profit margins of -175.83% and -106.37%.

Gross Margin 100.00%
Operating Margin -175.83%
Pretax Margin -106.35%
Profit Margin -106.37%
EBITDA Margin -172.34%
EBIT Margin -175.83%
FCF Margin 238.67%

Dividends & Yields

Septerna does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -347.46%
Shareholder Yield -347.46%
Earnings Yield -4.17%
FCF Yield 9.35%

Analyst Forecast

The average price target for Septerna is $38.14, which is 45.96% higher than the current price. The consensus rating is "Strong Buy".

Price Target $38.14
Price Target Difference 45.96%
Analyst Consensus Strong Buy
Analyst Count 7
Revenue Growth Forecast (5Y) 13.61%
EPS Growth Forecast (5Y) 24.18%
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

Septerna has an Altman Z-Score of 1.67 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.67
Piotroski F-Score 3