Silence Therapeutics plc (SLN)

NASDAQ: SLN · Real-Time Price · USD
7.31
+0.17 (2.38%)
Oct 28, 2025, 11:00 AM EDT - Market open
2.38%
Market Cap345.28M
Revenue (ttm)27.17M
Net Income (ttm)-79.13M
Shares Out 47.23M
EPS (ttm)-1.68
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume65,188
Open7.12
Previous Close7.14
Day's Range7.12 - 7.50
52-Week Range1.97 - 18.32
Beta1.38
AnalystsBuy
Price Target39.67 (+442.68%)
Earnings DateNov 13, 2025

About SLN

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Zerlasiran (SLN360), which is in Phase II clinical trial for cardiovascular disease associated with elevated lipoprotein(a); Divesiran (SLN124), an siRNA molecule that is in Phase I clinical trial for the treatment of genetic hematological conditions, includin... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 1994
Employees 116
Stock Exchange NASDAQ
Ticker Symbol SLN
Full Company Profile

Financial Performance

In 2024, Silence Therapeutics's revenue was $43.26 million, an increase of 36.71% compared to the previous year's $31.64 million. Losses were -$45.31 million, -16.45% less than in 2023.

Financial Statements

Analyst Summary

According to 6 analysts, the average rating for SLN stock is "Buy." The 12-month stock price target is $39.67, which is an increase of 442.68% from the latest price.

Price Target
$39.67
(442.68% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Silence Therapeutics Completes Enrollment in SANRECO Phase 2 Study of Divesiran for Polycythemia Vera (PV)

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced it h...

5 days ago - Business Wire

Silence Therapeutics Plc (SLN) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference Transcript

Silence Therapeutics plc (NASDAQ:SLN) Morgan Stanley 23rd Annual Global Healthcare Conference September 9, 2025 5:35 PM EDT Company Participants Michael Ulz - Equity Analyst Craig Tooman - President,...

6 weeks ago - Seeking Alpha

Silence Therapeutics to Participate in September Investor Conferences

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

2 months ago - Business Wire

Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

2 months ago - Business Wire

Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) th...

4 months ago - Business Wire

Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

6 months ago - Business Wire

Silence Therapeutics Welcomes Tim McInerney to Board of Directors

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

6 months ago - Business Wire

Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

8 months ago - Business Wire

Silence Therapeutics plc (SLN) Q4 2024 Earnings Call Transcript

Silence Therapeutics plc (NASDAQ:SLN) Q4 2024 Earnings Call February 27, 2025 8:00 AM ET Company Participants Gem Hopkins - Vice President, Investor Relations and Corporate Communications Craig Tooma...

8 months ago - Seeking Alpha

Silence Therapeutics Reports Full Year 2024 Financial Results and Provides Business Update

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

8 months ago - Business Wire

Silence Therapeutics to Report Fourth Quarter and Full Year 2024 Results on February 27, 2025

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

9 months ago - Business Wire

Top 3 Health Care Stocks That May Explode In Q4

The most oversold stocks in the health care sector presents an opportunity to buy into undervalued companies.

Other symbols: OLMA
11 months ago - Benzinga

Silence Therapeutics Presents Promising Phase 1 Data in Polycythemia Vera Patients at the American Society of Hematology (ASH) Annual Meeting

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) th...

11 months ago - Business Wire

Silence Therapeutics to Participate in Fireside Chat at Piper Sandler 36th Annual Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical stage biotechnology company committed to transforming people's l...

1 year ago - Business Wire

Silence Therapeutics' Zerlasiran Has Competitive Concerns: Analyst

On Monday, Silence Therapeutics plc SLN presented end-of-treatment data from its Phase 2 ALPACAR-360 study of zerlasiran in atherosclerotic cardiovascular disease (ASCVD) patients with high lipoprotei...

1 year ago - Benzinga

Top 3 Health Care Stocks You'll Regret Missing In Q4

The most oversold stocks in the health care sector presents an opportunity to buy into undervalued companies.

Other symbols: AMRNTERN
1 year ago - Benzinga

Silence Therapeutics Presents Late-Breaking Phase 2 Zerlasiran Data at 2024 American Heart Association (AHA) Annual Meeting

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical stage biotechnology company committed to transforming people's l...

1 year ago - Business Wire

Silence Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical stage biotechnology company committed to transforming people's l...

1 year ago - Business Wire

Silence Therapeutics to Participate in Fireside Chat at the Jefferies London Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical stage biotechnology company committed to transforming people's l...

1 year ago - Business Wire

Silence Therapeutics' RNAi Pipeline: Zerlasiran's Game-Changer Potential Is A 'Buy'

Silence Therapeutics focuses on RNA interference therapies, with its lead candidates targeting cardiovascular and hematological diseases via the mRNAi GOLD platform. Zerlasiran, the company's main val...

1 year ago - Seeking Alpha

Silence: Additional siRNA Drug Data Leads To Next Stages Of Development

Silence Therapeutics plc's positive results achieved from phase 1 SANRECO study using divesiran for the treatment of patients with polycythemia vera. The global polycythemia vera treatment market size...

1 year ago - Seeking Alpha

Silence Therapeutics to Webcast Presentations at Upcoming September Investor Conferences

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), an experienced and innovative biotechnology company committed to transforming peop...

1 year ago - Business Wire

Silence Therapeutics Reports Second Quarter 2024 Financial Results and Recent Business Highlights

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), an experienced and innovative biotechnology company committed to transforming peop...

1 year ago - Business Wire

Silence Therapeutics Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”), (Nasdaq: SLN), an experienced and innovative biotechnology company committed to transforming pe...

1 year ago - Business Wire

Silence Therapeutics Achieves $2 Million Research Milestone Payment from Hansoh Pharma Collaboration

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), an experienced and innovative biotechnology company committed to transforming peop...

1 year ago - Business Wire