Silence Therapeutics plc (SLN)
| Market Cap | 272.54M +46.9% |
| Revenue (ttm) | 839,000 -97.0% |
| Net Income | -75.04M |
| EPS | -1.61 |
| Shares Out | 47.23M |
| PE Ratio | n/a |
| Forward PE | n/a |
| Dividend | n/a |
| Ex-Dividend Date | n/a |
| Volume | 269,600 |
| Open | 6.04 |
| Previous Close | 6.23 |
| Day's Range | 5.74 - 6.27 |
| 52-Week Range | 4.19 - 8.40 |
| Beta | 1.52 |
| Analysts | Buy |
| Price Target | 31.20 (+440.73%) |
| Earnings Date | May 7, 2026 |
About SLN
Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN3... [Read more]
Financial Performance
In 2025, Silence Therapeutics's revenue was $559,000, a decrease of -98.71% compared to the previous year's $43.26 million. Losses were -$88.61 million, 95.6% more than in 2024.
Financial StatementsAnalyst Summary
According to 6 analysts, the average rating for SLN stock is "Buy." The 12-month stock price target is $31.2, which is an increase of 440.73% from the latest price.
News
Silence Therapeutics files $300M ordinary shares offering
16:11 EDT Silence Therapeutics (SLN) files $300M ordinary shares offering
Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that...
Silence Therapeutics price target lowered to $27 from $35 at Chardan
Chardan analyst Keay Nakae lowered the firm’s price target on Silence Therapeutics (SLN) to $27 from $35 and keeps a Buy rating on the shares. The firm updated the company’s…
Silence Therapeutics reports Q1 EPS (11c) vs. (20c) last year
Reports revenue $422,000 vs. $142,000 last year, “The Silence team continues to advance research supporting the broad potential of our mRNAi GOLD platform, and we remain well positioned as we…
Silence Therapeutics Highlights Recent Business Achievements and Reports First Quarter 2026 Financial Results
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financ...
Silence Therapeutics CEO Craig Tooman to end employment
Silence Therapeutics (SLN) announced that Craig Tooman, who has served as the company’s president, CEO and board member since 2022, agreed by mutual consent to end his employment with the…
Silence Therapeutics Announces Leadership Changes
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics to Participate in Fireside Chat at Jefferies Global Healthcare Conference
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that...
Silence Therapeutics reports Q3 EPS (15c), consensus (21c)
Reports Q3 revenue $159,000, consensus $3.28M. “Silence continues to focus on operational execution, highlighted by the rapid achievement of full enrollment in our ongoing SANRECO Phase 2 study of div...
Silence Therapeutics Reports Third Quarter 2025 Financial Results and Recent Business Highlights
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics completes patient enrollment in SANRECO
Silence Therapeutics (SLN) announced it has completed patient enrollment in the SANRECO Phase 2 study of divesiran, a first-in-class siRNA targeting TMPRSS6, for the treatment of polycythemia vera. In...
Silence Therapeutics Completes Enrollment in SANRECO Phase 2 Study of Divesiran for Polycythemia Vera (PV)
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced it h...
Silence Therapeutics to Participate in September Investor Conferences
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics reports Q2 EPS (19c), consensus (21c)
Reports Q2 revenue $224,000, consensus $3.38M. “The updated data we presented at EHA this past quarter were highly encouraging and supportive of the therapeutic potential of divesiran as a first-in-cl...
Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics presents additional Phase 1 data highlighting Divesiran
Silence Therapeutics (SLN) “presented additional data showcasing the SANRECO Phase 1 study of divesiran in patients with polycythemia vera at the European Hematology Association 2025 Annual Meeting in...
Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) th...
Silence Therapeutics reports Q1 EPS (20c), consensus (41c)
Reports Q1 revenue $142,000, consensus $3.58M. “Silence delivered another strong quarter focused on clinical and operational execution,” said Craig Tooman, President and Chief Executive Officer at Sil...
Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics Welcomes Tim McInerney to Board of Directors
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference
LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or the “Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...
Silence Therapeutics price target lowered to $30 from $31 at Jefferies
Jefferies analyst Kelly Shi lowered the firm’s price target on Silence Therapeutics (SLN) to $30 from $31 and keeps a Buy rating on the shares following Q4 earnings. The analyst…
Silence Therapeutics reports FY25 net loss 33c vs. 49c loss last year
DJ Silence Therapeutics (SLN) 2024 Loss/Shr 33c “2024 was marked by strong clinical execution and pipeline advancement, highlighting the broad potential of our mRNAi GOLD platform to silence disease c...
Silence Therapeutics extends projected cash runway into 2027
Silence announced today that it will only initiate the zerlasiran Phase 3 CVOT study once a partner is secured. Following this announcement, Silence is extending its projected cash runway into…