Spruce Biosciences, Inc. (SPRB)

Spruce Biosciences Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	May 28, 2026	Dec 31, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021
Market Cap	133	120	18	120	26	105
Market Cap Growth	4262.70%	573.89%	-85.25%	364.30%	-75.29%	-81.47%
Enterprise Value	86.88	71.03	-20.16	26.61	-48.63	21.98
Last Close Price	49.19	87.11	31.50	219.75	82.28	334.50
PS Ratio	-	-	3.61	11.92	-	-
PB Ratio	1.96	0.36	0.62	1.57	0.38	0.94
P/TBV Ratio	0.14	0.20	0.60	1.48	0.38	0.94
EV/Sales Ratio	-	-	-4.10	2.64	-	-
EV/EBITDA Ratio	-	-	0.36	-	1.03	-
EV/EBIT Ratio	-	-	0.36	-	1.03	-
EV/FCF Ratio	-	-	0.36	-	1.17	-
Debt / Equity Ratio	0.02	0.00	0.03	0.04	0.07	0.06
Net Debt / Equity Ratio	-0.14	-0.15	-1.26	-1.20	-1.06	-0.74
Net Debt / EBITDA Ratio	1.40	1.33	0.65	1.77	1.54	1.97
Net Debt / FCF Ratio	1.61	1.46	0.65	2.76	1.75	2.30
Asset Turnover	-	0	0.07	0.11	0	0
Quick Ratio	4.59	4.85	2.54	3.94	6.35	10.03
Current Ratio	4.67	5.17	2.90	4.18	6.72	10.36
Return on Equity (ROE)	-3.67%	-21.61%	-100.70%	-66.10%	-51.35%	-32.43%
Return on Assets (ROA)	-62.29%	-74.34%	-75.29%	-54.85%	-44.58%	-29.07%
Return on Invested Capital (ROIC)	463.67%	555.80%	641.98%	713.26%	-387.69%	-309.65%
Return on Capital Employed (ROCE)	-77.90%	-100.18%	-102.61%	-68.11%	-49.56%	-31.08%
Buyback Yield / Dilution	-72.07%	-39.34%	-7.14%	-63.68%	-0.71%	-289.93%
Total Shareholder Return	-72.07%	-39.34%	-7.14%	-63.68%	-0.71%	-289.93%

Updated May 13, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.