Talphera, Inc. (TLPH)

NASDAQ: TLPH · Real-Time Price · USD
0.8675
-0.0362 (-4.01%)
At close: May 11, 2026, 4:00 PM EDT
0.8730
+0.0055 (0.63%)
After-hours: May 11, 2026, 7:37 PM EDT
Market Cap45.02M +442.4%
Revenue (ttm)28,000
Net Income-14.29M
EPS-0.34
Shares Out 51.90M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume234,106
Open0.9043
Previous Close0.9037
Day's Range0.8485 - 0.9242
52-Week Range0.3800 - 1.5700
Beta0.79
AnalystsStrong Buy
Price Target3.00 (+245.82%)
Earnings DateMay 13, 2026

About TLPH

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company’s lead product candidate, Niyad, is a lyophilized formulation of nafamostat that acts as a regional anticoagulant for infusion into the extracorporeal circuit. It is also developing LTX-608, a lyophilized vial containing nafamostat for IV infusion for disseminated intravascular coagulation, acute respiratory distress syndrome, acute pancreatitis, and an anti-viral treatment; Feds... [Read more]

Sector Healthcare
IPO Date Feb 14, 2011
Employees 12
Stock Exchange NASDAQ
Ticker Symbol TLPH
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to one analyst, the rating for TLPH stock is "Strong Buy" and the 12-month stock price target is $3.0.

Price Target
$3.0
(245.82% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Talphera to Host First Quarter Financial Results and Corporate Update Call and Webcast on Wednesday, May 13, 2026

SAN MATEO, Calif., May 7, 2026 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies ...

4 days ago - PRNewsWire

Talphera initiated with a Buy at WestPark Capital

WestPark Capital analyst Ed Arce initiated coverage of Talphera (TLPH) with a Buy rating and $3 price target The firm says the company is brining the best continuous renal replacement…

11 days ago - TheFly

Talphera Announces Two Abstracts Accepted for Presentation at AKI & CRRT 2026

SAN MATEO, Calif., March 25, 2026 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapi...

6 weeks ago - PRNewsWire

Talphera files to sell 639,931 shares of common stock for holders

06:03 EDT Talphera (TLPH) files to sell 639,931 shares of common stock for holders

6 weeks ago - TheFly

Talphera Earnings Call Transcript: Q4 2025

The Nephro CRRT study reached 50% enrollment, unlocking $4.1M in financing and progressing toward FDA approval for Niyad. Experts highlight significant operational and safety limitations with current CRRT anticoagulants, anticipating that Niyad could become the preferred option due to its simplicity and effectiveness.

7 weeks ago - Transcripts

Talphera reports Q4 EPS (6c) vs. (7c) last year

Reports cash and investments of $20.4M at December 31, 2025. “Earlier this month, we communicated reaching the 35-patient enrollment mark in the 70-patient nafamostat registrational study for CRRT. Si...

7 weeks ago - TheFly

Talphera Announces Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

Previously announced achievement of 50% enrollment of the NEPHRO CRRT clinical study in March 2026 and closed the associated financing tranche of $4.1 million All 12 clinical study sites now able to e...

7 weeks ago - PRNewsWire

Talphera to Host Virtual Investor & Analyst Event to Discuss Niyad® for Use in Continuous Renal Replacement Therapy (CRRT), on March 23, 2026

SAN MATEO, Calif., March 18, 2026 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapi...

7 weeks ago - PRNewsWire

Talphera announces 50% patient enrollment of the NEPHRO-CRRT clinical trial

Talphera (TLPH) announced 50% patient enrollment of the NEPHRO-CRRT clinical trial. “Over the course of 2025, with agreement from the FDA, we implemented significant changes to the NEPHRO CRRT clinica...

2 months ago - TheFly

Talphera Announces 50% Enrollment Milestone in Ongoing NEPHRO-CRRT Registrational Trial

Enrolled 35 of the 70 patients in the ongoing NEPHRO-CRRT registrational study, supported by new target profile sites Company to host a virtual investor and analyst event on March 23 at 11:00 am ET fe...

2 months ago - PRNewsWire

Talphera Earnings Call Transcript: Q3 2025

NEPHRO study enrollment accelerated after protocol changes, but delays in activating new high-volume sites have shifted expected completion to H1 2026. Cash position and recent financing provide runway through anticipated Niyad PMA approval, with operating expenses reduced year-over-year.

6 months ago - Transcripts

Talphera reports Q3 EPS (11c) vs. (13c) last year

Reports Q3 revenue $1K vs. $0 last year. “The financing closed in September, led by a strategic investment from CorMedix, combined with future conditional tranches, is expected to provide us…

6 months ago - TheFly

Talphera Announces Third Quarter 2025 Financial Results and Provides Corporate Update

Closed $17 million first tranche financing led by a strategic investment from CorMedix, Inc. Cash and investments at September 30, 2025 were $21.3 million; combined with conditional future tranches of...

Other symbols: CRMD
6 months ago - PRNewsWire

Talphera to Host Third Quarter Financial Results and Corporate Update Call and Webcast on Wednesday, November 12, 2025

SAN MATEO, Calif. , Nov. 5, 2025 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapie...

6 months ago - PRNewsWire

Talphera files to sell 1.02M shares of common stock for holders

The company is not selling any of its common stock pursuant to this prospectus, and will not receive any proceeds from the sale of its common stock offered by this…

6 months ago - TheFly

Talphera Announces the Appointment of Joe Todisco to Board of Directors

SAN MATEO, Calif. , Oct. 21, 2025 /PRNewswire/ -- Talphera, Inc. (Nasdaq: TLPH), (Talphera), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies...

7 months ago - PRNewsWire

Talphera files to sell 25.04M shares of common stock for holders

Also files to sell 5.85M shares of common stock issuable upon exercise of pre-funded warrants for holders.

8 months ago - TheFly

CorMedix makes $5M minority equity investment in Talphera

CorMedix (CRMD) made a $5M strategic minority equity investment in Talphera, (TLPH), acquiring 9,090,909 shares at an at-market price of $0.55 per share as part of Talphera’s concurrently announced pr...

Other symbols: CRMD
8 months ago - TheFly

CorMedix Announces Strategic Minority Investment in Talphera

BERKELEY HEIGHTS, N.J., Sept. 08, 2025 (GLOBE NEWSWIRE) -- CorMedix Inc. (“CorMedix”) (Nasdaq: CRMD), a biopharmaceutical company focused on developing and commercializing therapeutic products for lif...

Other symbols: CRMD
8 months ago - GlobeNewsWire

Talphera Announces Private Placement Financing of up to $29 Million Priced At-the Market

CorMedix is making a strategic investment in Talphera as the lead investor, supported by existing stockholders Nantahala, Rosalind and Rock Springs with several new institutional investors $17 million...

Other symbols: CRMD
8 months ago - PRNewsWire

Talphera enrolls 17 patients in 70-patient pivotal NEPHRO CRRT clinical trial

Talphera (TLPH) announced the enrollment of 17 patients in its 70-patient pivotal NEPHRO CRRT clinical trial. The enrollment of 17 patients is a milestone that was required to be achieved,…

9 months ago - TheFly

Talphera Announces Achievement of 17 Patient Enrollment Milestone in NEPHRO CRRT Pivotal Trial

The NEPHRO CRRT pivotal trial has now reached approximately 25% enrollment, driven by the recent acceleration in the recruitment rate from new profile clinical sites On track for planned study complet...

9 months ago - PRNewsWire

Talphera Earnings Call Transcript: Q2 2025

NEPHRO study enrollment accelerated with new site strategy, reducing study size and operating expenses. Cash and expected financing should fund operations through study completion, with strong market demand for Nafamostat amid ongoing heparin and citrate shortages.

9 months ago - Transcripts

Talphera reports Q2 EPS (10c) vs. (15c) last year

Cash and cash equivalents at June 30, 2025 were $6.8M. “We have enrolled 15 patients in the NEPHRO clinical study and based on the recent accelerated rate of enrollment, we…

9 months ago - TheFly

Talphera lowers 2025 cash operating expense view to $16M-$17M from $17M-$19M

16:12 EDT Talphera (TLPH) lowers 2025 cash operating expense view to $16M-$17M from $17M-$19M

9 months ago - TheFly