Vertex Pharmaceuticals Incorporated (VRTX)

Vertex Pharmaceuticals Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Nov 26, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Market Capitalization	109,650	103,707	104,849	74,127	55,834	61,457
Market Cap Growth	-15.14%	-1.09%	41.44%	32.76%	-9.15%	9.16%
Enterprise Value	99,475	94,253	91,965	65,181	49,750	55,853
Last Close Price	432.17	402.70	406.89	288.78	219.60	236.34
PE Ratio	30.39	-	28.97	22.31	23.84	22.66
Forward PE	21.47	22.66	24.44	18.83	16.42	21.78
PS Ratio	9.46	9.41	10.62	8.30	7.37	9.90
PB Ratio	6.34	6.32	5.96	5.33	5.53	7.08
P/TBV Ratio	6.94	7.15	6.70	6.07	6.42	8.44
P/FCF Ratio	32.86	-	31.42	18.89	23.18	20.53
P/OCF Ratio	29.49	-	29.64	17.95	21.12	18.89
PEG Ratio	0.07	1.21	1.92	0.58	1.62	1.06
EV/Sales Ratio	8.49	8.55	9.32	7.30	6.57	9.00
EV/EBITDA Ratio	21.11	20.59	20.54	14.40	12.38	17.66
EV/EBIT Ratio	21.93	21.45	21.35	14.89	12.78	18.29
EV/FCF Ratio	29.81	-	27.56	16.61	20.66	18.66
Debt / Equity Ratio	0.11	0.11	0.05	0.07	0.10	0.11
Debt / EBITDA Ratio	0.37	0.37	0.18	0.20	0.24	0.30
Debt / FCF Ratio	0.55	-	0.24	0.23	0.40	0.32
Asset Turnover	0.50	0.49	0.48	0.57	0.60	0.62
Inventory Turnover	4.10	5.31	7.38	8.87	8.97	10.62
Quick Ratio	1.84	2.17	3.60	4.46	4.04	4.02
Current Ratio	2.36	2.69	3.99	4.83	4.46	4.33
Return on Equity (ROE)	22.31%	-3.15%	22.99%	27.67%	24.93%	36.71%
Return on Assets (ROA)	12.04%	12.14%	13.17%	17.33%	19.32%	19.02%
Return on Capital (ROIC)	15.51%	15.03%	16.22%	21.15%	23.51%	23.29%
Return on Capital Employed (ROCE)	22.30%	23.20%	22.50%	28.40%	34.50%	30.90%
Earnings Yield	3.35%	-0.52%	3.45%	4.48%	4.20%	4.41%
FCF Yield	3.04%	-0.76%	3.18%	5.29%	4.31%	4.87%
Buyback Yield / Dilution	-0.11%	1.00%	-0.54%	0.31%	1.33%	-1.04%

Updated Nov 3, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q