Vertex Pharmaceuticals Incorporated (VRTX)

Vertex Pharmaceuticals Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Dec 18, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Market Capitalization	113,509	103,707	104,849	74,127	55,834	61,457
Market Cap Growth	-5.36%	-1.09%	41.44%	32.76%	-9.15%	9.16%
Enterprise Value	103,334	94,253	91,965	65,181	49,750	55,853
Last Close Price	447.38	402.70	406.89	288.78	219.60	236.34
PE Ratio	31.46	-	28.97	22.31	23.84	22.66
Forward PE	22.29	22.66	24.44	18.83	16.42	21.78
PS Ratio	9.79	9.41	10.62	8.30	7.37	9.90
PB Ratio	6.56	6.32	5.96	5.33	5.53	7.08
P/TBV Ratio	7.18	7.15	6.70	6.07	6.42	8.44
P/FCF Ratio	34.01	-	31.42	18.89	23.18	20.53
P/OCF Ratio	30.53	-	29.64	17.95	21.12	18.89
PEG Ratio	0.15	1.21	1.92	0.58	1.62	1.06
EV/Sales Ratio	8.81	8.55	9.32	7.30	6.57	9.00
EV/EBITDA Ratio	21.93	20.59	20.54	14.40	12.38	17.66
EV/EBIT Ratio	22.78	21.45	21.35	14.89	12.78	18.29
EV/FCF Ratio	30.96	-	27.56	16.61	20.66	18.66
Debt / Equity Ratio	0.11	0.11	0.05	0.07	0.10	0.11
Debt / EBITDA Ratio	0.37	0.37	0.18	0.20	0.24	0.30
Debt / FCF Ratio	0.55	-	0.24	0.23	0.40	0.32
Asset Turnover	0.50	0.49	0.48	0.57	0.60	0.62
Inventory Turnover	4.10	5.31	7.38	8.87	8.97	10.62
Quick Ratio	1.84	2.17	3.60	4.46	4.04	4.02
Current Ratio	2.36	2.69	3.99	4.83	4.46	4.33
Return on Equity (ROE)	22.31%	-3.15%	22.99%	27.67%	24.93%	36.71%
Return on Assets (ROA)	12.04%	12.14%	13.17%	17.33%	19.32%	19.02%
Return on Capital (ROIC)	15.51%	15.03%	16.22%	21.15%	23.51%	23.29%
Return on Capital Employed (ROCE)	22.30%	23.20%	22.50%	28.40%	34.50%	30.90%
Earnings Yield	3.24%	-0.52%	3.45%	4.48%	4.20%	4.41%
FCF Yield	2.94%	-0.76%	3.18%	5.29%	4.31%	4.87%
Buyback Yield / Dilution	-0.11%	1.00%	-0.54%	0.31%	1.33%	-1.04%

Updated Nov 3, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q