Company Description
Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States.
Its product candidates are Avutometinib, an orally available small molecule RAF/MEK clamp that inhibits the ras sarcoma RAF/MEK, ERK mitogen activated pathway kinase pathway which is involved in cell proliferation, migration, transformation, and survival of tumor cells; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors.
The company is involved in clinical studies, including RAMP 301, a randomized global confirmatory trial to evaluate the combination of Avutometinib and Defactinib for the treatment of patients with recurrent low-grade serous ovarian cancer; RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of Avutometinib and in combination with Defactinib; and FRAME, an investigation of Avutometinib and Defactinib in patients with KRAS mutant cancers and subsequent analyses; and RAMP 204 and 205.
It has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing Avutometinib; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer’s inhibitors of FAK for therapeutic, diagnostic, and prophylactic uses in humans.
In addition, it has a clinical collaboration agreement with Amgen, Inc. to evaluate the combination of Avutometinib with Amgen’s KRAS-G12C inhibitor LUMAKRAS which in Phase 1/2 trial entitled RAMP 203; and a discovery and development collaboration with GenFleet Therapeutics to advance new programs targeting RAS pathway-driven cancers.
Verastem, Inc. was incorporated in 2010 and is headquartered in Needham, Massachusetts.
Country | United States |
Founded | 2010 |
IPO Date | Jan 27, 2012 |
Industry | Biotechnology |
Sector | Healthcare |
Employees | 73 |
CEO | Daniel Paterson |
Contact Details
Address: 117 Kendrick Street, Suite 500 Needham, Massachusetts 02494 United States | |
Phone | 781 292 4200 |
Website | verastem.com |
Stock Details
Ticker Symbol | VSTM |
Exchange | NASDAQ |
Fiscal Year | January - December |
Reporting Currency | USD |
CIK Code | 0001526119 |
CUSIP Number | 92337C104 |
ISIN Number | US92337C2035 |
Employer ID | 27-3269467 |
SIC Code | 2834 |
Key Executives
Name | Position |
---|---|
Daniel W. Paterson | President, Chief Executive Officer and Director |
Daniel Calkins | Chief Financial Officer and Principal Accounting and Financial Officer |
Richard H. Aldrich M.B.A. | Founder and Consultant |
Dr. Robert A. Weinberg Ph.D. | Co-Founder and Chair of Scientific Advisory Board |
Dr. Piyush B. Gupta Ph.D. | Co-Founder |
Dr. Michelle Dipp M.D., Ph.D. | Co-Founder |
Dr. Jonathan Pachter Ph.D. | Chief Scientific Officer |
Cathy Carew | Chief Organizational Effectiveness Officer |
Nate Sanburn | Chief Business Officer |
Michael Crowther | Chief Commercial and Strategy Officer |
Latest SEC Filings
Date | Type | Title |
---|---|---|
Oct 24, 2024 | SC 13G | Statement of acquisition of beneficial ownership by individuals |
Oct 17, 2024 | 8-K | Current Report |
Aug 8, 2024 | 10-Q | Quarterly Report |
Jul 29, 2024 | SC 13G | Statement of acquisition of beneficial ownership by individuals |
Jul 25, 2024 | 8-K | Current Report |
Jul 24, 2024 | 424B5 | Filing |
Jul 23, 2024 | 424B5 | Filing |
Jul 23, 2024 | 8-K | Current Report |
Jun 26, 2024 | 8-K | Current Report |
May 30, 2024 | S-8 | Securities to be offered to employees in employee benefit plans |