Hello, everyone, and thank you for joining 111's conference call today. On the call today from the company are Dr. Gang Yu, co-founder and executive chairman, Mr. Junling Liu, co-founder, chairman, and CEO, Mr. Luke Chen, CFO of 's major subsidiary, and Mr. Harvey Wang, COO. As a reminder, today's conference call is being broadcast live via webcast. The company's earnings press release was distributed earlier today, and together with the earnings press release, are available on the company's IR website. Before the conference call gets started, let me remind you that this call may contain forward-looking statements made under the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995.
Such statements are based upon management's current expectations and current market and operating conditions and relate to events that involve known and unknown risks, uncertainties, and other factors, all of which could cause actual results to differ materially. For more information about these risks, please refer to the company's filings with the SEC. 111 does not undertake any obligation to update any forward-looking statements as a result of new information, future events, or otherwise, except as required under applicable law. Please note that all numbers are in RMB and all comparisons refer to year-over-year comparisons unless otherwise stated. Please also refer to the earnings press release for detailed information of the comparative financial performance on a year-over-year basis. With that, I will turn the call over to 111 CEO, Mr. Junling Liu. Please go ahead.
Good morning and good evening, everyone. Thank you for joining our fourth quarter and the fiscal year 2022 earnings call. The information that we'll be discussing here are also provided in the slides that have been posted earlier today on the company's website. I'd like to encourage you to download the presentation along with the earnings report at ir.111.com.cn. In today's call, I will talk about some of the latest regulatory developments in the healthcare industry and what it means to the company. I'll also cover our strategies for building growth momentum, improving operational efficiency, and strengthening supply base. I'll spend some time to speak about the performance of Q4 and the full year of 2022 before handing the call to Mr. Luke Chen, who will walk you through our financial results. 2022 proved to be a very challenging year for many businesses, including 111.
Everyone in China is thankful that COVID is behind us and anxious to get on with life as per normal. One of the most important trends post-pandemic will be the digitization of the healthcare industry. COVID-19 pandemic has shown how important healthcare services are in society, but it has also highlighted the limitations of the traditional healthcare services. With the introduction of digital technology, healthcare services have become more accessible for both consumers and businesses. With digital tools and platforms, healthcare providers can increase access to care, improve patient outcomes, and better manage the challenges posted by public health emergencies. Digital technology has emerged as one of the key capabilities in solving the uncertain disturbance factors of the COVID-19 pandemic. The importance of digital technology in healthcare is likely to increase in the future, and thus its usage will continue as a critical trend in the healthcare industry.
In May 2022, the State Council of China issued the 14th Five-Year Plan for national health, which clearly proposed to accelerate the construction of national health informatization, promote information interconnection, and the construction of Internet hospitals, Internet-class chronic disease management, and other projects. This is expected to help improve access to healthcare for people in remote areas as well as streamline healthcare services. In June 2022, the National Health Commission of China issued the rules of the supervision of Internet Diagnosis and Treatment, which further provided new guidelines for the development of Internet Diagnosis and Treatment norms. In September 2022, the State Administration for Market Regulation issued the Measures for the Supervision and Administration of Drug Network Sales, which provided clearer requirements for the high-quality development of the pharmaceutical e-commerce industry. In October 2022.
2022, the report of the 20th National Congress of the Communist Party of China clearly pointed out that high-quality development is the primary task of building a socialist modern country in all around way. As one of the four key directions of people's well-being, healthcare industry is regarded as a strategic priority for development. With the increasing adoption of digital technology, the healthcare industry has been undergoing significant advancements towards digital transformation. As the nation is quickly approaching an aging society, one can bet that healthcare expenditure from both the government and personal wallet will grow at a fast pace. All those policies will become tremendous payment in our business. 111 aims to create a leading digital healthcare platform in China, with a mission to connect patients with medicine and healthcare services digitally.
The platform offers a wide range of healthcare services, including consultations, diagnosis, delivery of medicine, tools to enable both upstream pharmaceutical manufacturers and downstream pharmacies. Consumers can access these services through the digital platform, enabling them to receive medical advice and consultation services from the safety of their homes. Businesses can leapfrog the traditional way of conducting business and can access a range of services digitally with much greater efficiency. This digital platform has made healthcare services more accessible, convenient, and affordable for individuals and businesses with great user experience. Based on the rapid development in the past few years, the company's development strategy has begun to shift from expanding scale and acquiring customers to pursuing businesses with higher value, focusing on value creation, better customer experience, and a stronger supply base.
In order to achieve the above, the company realigns operations with the goals set in the three areas. When it comes to new projects, the decision-making process starts from the value it can create for upstream and downstream customers. Proof of concept also comes from feedback from real customers instead of management imagining in the isolation of office. Ideas and projects always fight for attention in order to ensure that they're always creating maximum value for their customers. Management emphasizes competition on the basis of value creation. This could be measured in a number of ways, including increased efficiency, improved outcomes, or a better overall experience. Projects that have the greatest potential to create significant value for customers are prioritized over those that are likely to provide fewer benefits.
Once a project has been approved, management ensures that the team working on it is fully focused on delivering maximum value at every stage of development. Throughout the project lifecycle, value creation is a key consideration. Teams are given specific metrics to track their progress and ensure that the project is meeting its goals. Perhaps most importantly, feedback from the customers is constantly solicited and incorporated into the project's development process. This helps to ensure that the final product is fully aligned with the needs of 111's customers and provides them with the best possible experience. Being customer-centric is at the heart of the renewed operation structure. In the past, there have been numerous times when weekly business review metrics are more centered around internal metrics such as revenue and margin. That was changed to metrics related to things like, do we have what customers want?
Is the pricing competitive enough? Do they always come back to us? Do they recommend our service to others? All teams will have to go through their own operational metrics to align with customer needs. For instance, a fulfillment center manager will need to reform his or her metrics around how fast do they receive goods, how fast can they deliver to customers, how many items got damaged during transportation, how many complaints are received on a day-to-day basis. The company believes that long-term value is much more important than short-term revenue and margin gains. To achieve long-term value, everyone in the company has to have the mentality that customers come first. With great efforts over the last few years, a decent supplier base has been built, but the company believes, moving forward, this supplier base needs to be further strengthened.
Although great relationships with major suppliers have been established, true strategic relationships need further development. This comes back to the point of value creation. The company has the state-of-the-art technology with many modules scattered in different silos of operations. Once we can integrate all those modules, much greater value can be created. Suppliers can leverage our digital tools to have real-time data on their products' coverage, sales, and pricing. Traditionally, they could only get sales in figures from tier one distributors. Now they have complete view of business through the lenses of our digital tools. Clearly, those kinds of digital benefits were never available to the pharmaceutical manufacturers in the past. At best, they have some limited data on a few key customers with direct coverage if they are big enough with a ground sales team.
Without surprise, almost all of the suppliers who have seen our digital solutions are delighted by its capabilities. If we continue to deliver such solutions to our upstream suppliers, they'll be more and more interested in allocating more resources to one-one-one as a digital channel. Over time, our supply base will be strong enough to compete against those well-established traditional players. The partnership will be based on who can deliver more value to suppliers other than previously established long-term relationships. As the digital catalyst in the healthcare industry, 111 has rapidly developed its core competence by digitally connecting key players in this ecosystem. This makes it possible for digital technology to become enabler for those players to improve their respective efficiency. With more and more players adopting digital technology, the industry is being transformed.
There is a popular terminology in China called the Industrial Internet, which should be translated as an industry that's being transformed by internet technology. We have laid a very solid foundation and a position 111 as one of the most important players in the field to internetize this very traditional industry. Now let me spend a moment to talk about the key business progress of 111 in both Q4 and the whole year of 2022. Over the past 12 months, the deepened partnership with upstream and downstream companies continued to expand. Upstream, we have reached direct supply relationship with more than 500 global and domestic pharmaceutical companies, which provides abundant supply of drugs, more competitive costs, and more stable supply, and support us to help drugstore partners build a more competitive assortment portfolio and improve the gross profit of products.
Downstream, we provided services to more than 435,000 retail pharmacies. This is around 75% market penetration, providing our pharmaceutical partners in-depth market reach of drug commercialization in the broad market, reducing distribution costs and achieving coverage more than 890 cities and counties in China within 24 hours. Directly or indirectly providing medical services to hundreds of millions of consumers. We always adhere to the principle that digital technology can effectively improve the efficiency of the industry. In 2022, our technology R&D expenditure reached RMB 140 million with a total R&D expenditure of RMB 421 million in the past three years. By the end of 2022, 111 owns 9 core intelligence systems, independently developed more than 30 proprietary systems.
We were awarded 19 invention patents and have made breakthrough innovations in intelligent supply chain and big data analysis. In 2022, 111 was once again awarded the honorary titles and the qualifications of High-tech Enterprise certified by the Ministry of Science and Technology, National E-commerce Demonstration Enterprise by the Ministry of Commerce, Special and New Enterprise by Shanghai City Government and the Pudong Area New R&D Institution by Pudong government. We don't live in the delusion that the fame and the recognition can translate into business results. The reason why we invest in technology is because we truly believe that technology can bring operational efficiency. We want this to be a core strength of 111. Therefore, we are confident that we will be able to compete in such a crowded industry.
Even with current scale, which is relatively small compared to the few big establishments, we can already compete on operational efficiency. OpEx will be a very key metric to tell how efficient a company can be. We continue to grow in scale, we believe we can run this operation at a much lower rate. The significance of this is that we will be the most efficient operator in the whole industry, which will enable us to compete effectively with the big boys. One of our strategies moving forward is to continue to build an operation with the lowest cost structure as we want to be the most efficient operator in our space. Innovation is one of the core tenets of our corporate culture, and it continues to be the driver for future growth.
In the B2B sector, we pioneered the One Health project to more than 12,000 drugstores through digital franchise. The franchise drugstores can use digital SaaS services, including intelligent procurement, O2O, CRM, et cetera, to better manage drug selection, procurement, inventory management, and customer relationship. Under One Health project, 111 can deliver value to upstream pharmaceutical companies and downstream pharmacies. This model makes it the most efficient way for drugs to reach the hands of consumers or manufacturers as the whole process is digital and transparent. Our mission has always been to digitally connect drugs and healthcare services to consumers. The proliferation of One Health is a step forward in our mission. In the B2C sector, based on the digital platform and the chronic disease management capability, 111 is helping drug manufacturers to launch their drugs on our platform.
On February 16th, the first official flagship store of Hua medicine went live on 111's platform. Immediately, Hua's Glitazone, the very first locally approved innovative diabetic oral drug in China, received nationwide coverage. Which means patients across the whole country can access the drug on our platform from day one of the launch. 111 also helps pharma medicine to manage lifecycle of patient care, including initial drug fulfillment, follow-on patient education, drug adherence management, online assistance of patient questions and refill. We're proud of the fact that our model not only can help patients in accessing newly launched drugs regardless of where they live in the country, but also enable upstream drug manufacturers to leverage our digital capabilities to reach more patients and manage them with digital tools to achieve better business results. Now let's move on to our fourth quarter and full year 2022 results.
In Q4, our operating revenue amounted to RMB 4.1 billion, representing a year-on-year increase of 19.9%. This is the 18th consecutive quarter of growth since company's IPO. Q4's gross profit increased by 23.8% year-on-year. Gross profit margin increased from 5.9% in the same period last year to 6.1%. Q4 generated positive cash flow of RMB 63.2 million from operating activities, the second consecutive quarter of positive cash flow. From RMB 959 million in 2017 to RMB 13.5 billion in 2022, our revenue scale has rapidly expanded 14 times in five years. In 2022, our total revenue reached RMB 13.5 billion, an increase of 8.8% year-on-year.
Gross profit increased by 35.2% year-over-year, four times the growth rate of revenue. The gross profit margin increased from 5% last year to 6.2% this year. Let's not forget the struggles we had to endure throughout the whole year with COVID zero restrictions. For majority of the year, our operations were disrupted in many ways. I won't bore you with much details, but the 9% revenue growth and 35% margin growth is earned with tremendous team effort. Meanwhile, Q4 non-GAAP operation loss narrowed to 0.96% of net income from 2.22% in the same period last year. In fact, we achieved the profitability in December of 2022. Throughout 2022, our operational efficiency continued to improve.
Total sales and marketing expenses, general administrative expenses, and technology expenses decreased by 15.5% year-on-year. non-GAAP operating loss narrowed to 1.6% of net income for the full year from 4% in the same period last year. As of December 31, 2022, cash and cash equivalents, restricted cash and shorts on investments totaled RMB 922.7 million. I'd like to spend a minute to quickly talk about our ESG efforts. Over the past year, with the advantages of digital technology and integrated online and offline platform, the company has actively helped fight the pandemic. During the lockdown, the government appointed a small number of companies to deliver essential goods to residents who are locked down at home. 111 was appointed as one of the critical living guarantee enterprises in Shanghai.
The company set up a virtual pandemic control command center as soon as the pandemic broke out in Shanghai in early 2022, mobilizing resources from 111 to help our community. We collected purchase orders via proprietary purchase channels and assigned special personnel to process them, thus ensuring on-time delivery to patients. one Clinic, 111's online hospital, launched free online services since the pandemic began and provided free online consultations, free prescription renewal for chronic disease sufferers, and other medical services to the public. The company has proactively organized donations and offered anti-pandemic PPEs for enterprises resuming work and production. In the context of the post-COVID economic promotion measures, 111 was again picked by the government as the designated healthcare platform in the Shanghai Electronic Consumption Voucher campaign in 2022.
We provided services and offered citizens of Shanghai to redeem vouchers on our digital platform, helping government and the residents in consumption recovery. Everyone at 111 is proud to be able to contribute to the community. In the future, we will always firmly fulfill our social responsibilities and make continuous efforts to actively contribute to the construction of a healthy China. What a year we had. In a way, we're very glad 2022 is behind us, and COVID-19 has become vague memories. We overcame so many challenges and fought so hard for our business and achieved great results. We grew revenue and margin under extremely difficult circumstances. Operating expenditure continues to show great trends, which suggests that our operational efficiency will continue to improve. Our bottom line is trending towards breakeven.
In fact, we achieved the profitability at a non-GAAP operating level in the month of December 2022. In short, we have made significant progress in all business metrics. We believe that our strong technical capabilities will continue to enable us to build scale and improve efficiency, which will create long-term and a sustained revenue and margin growth. Looking to the future, 111 will continue to operate on the principles value creation, being customer-centric, and strengthening its supplier base. We believe the government will continue to support the healthcare industry's digital migration. The national strategy of strengthening the Digital China infrastructure and the policies of the 14th Five-Year Plan and the goals for 2035 provided us with excellent regulatory tailwinds, and we're excited that we can play an important role of speeding up the digital transformation of healthcare industry.
We will double down our efforts in growing revenue and margin, improve our operational efficiency, and achieve profitability. Considering our track record over the last four years, we have proven our capability in executing our strategy. We will continue to embed our delivering great results in the future. We wish to thank all the investors who have supported us all along. I'll hand the call to our CFO, Mr. Luke Chen, to walk through our financial results. Thank you.
Thank you, Junling. Good morning or evening, everyone. I want to begin by thanking all of our colleagues for their resilience and hard work over fiscal year 2022 as we navigated a challenging environment for making necessary changes to improve our operation and cost efficiency while maintaining our competitive edge. Moving to the financials. My prepared remarks will focus on a few key business and financial highlights. You can refer to the details of the fourth quarter and the fiscal year 2020 results from slide 19-22 in Section 3 of our presentation. All comparisons are year-over-year, and all numbers are in RMB, unless otherwise stated. Let's start with the fourth quarter results. Total net revenues for the quarter grew 20% to RMB 4.1 billion.
We are pleased to report that our gross segment profit for the quarter has grown at 24%, which is faster than the revenue growth. Strong top-line growth for the quarter was mainly attributed to our B2B segment revenue growth at 21% to RMB 4 billion. The gross segment profit for B2B segment has increased 31%, with gross segment margin up from 5.2% to 5.6%, which reflected our ability to rapidly expand our business scale while steadily improve our margin. Our B2C segment revenue decreased 2% to RMB 126 billion, with gross segment margin at 21%. Total operating expenses for the quarter were up 17% to RMB 363 million.
As a percentage of net revenue, total operating expenses for the quarter was down to 8.8% from 9% as we continue to enhance our operating leverage and optimize our operational efficiency. Fulfillment expenses as a percentage of net revenue for the quarter were 2.9%, as compared to 3% in the same quarter of last year. Excluding the share-based compensation, sales and marketing expenses as a percentage of net revenue for the quarter was 2.7%, down from 3.4% in the same quarter of last year. G&A expenses accounted for 0.9% of net revenue, down from 1%. The technology expenses accounted for 0.6% of net revenue as compared to 0.7% in the same quarter of last year.
As a result, the net GAAP loss from operations for the quarter narrowed to RMB 40 million compared to the loss of RMB 77 million in the same quarter of last year. As a percentage of net revenues, the net GAAP loss from operations decreased to less than 1% in the quarter, from 2.2% in the same quarter of last year. The net GAAP net loss attributable to ordinary shareholders was RMB 46 million, compared to RMB 84 million in the same quarter of last year. As a percentage of net revenues, the net GAAP net loss attributable to ordinary shareholders decreased to 1.1% in the quarter from 2.4% in the same quarter of last year. As for our fiscal full year 2022, I would like to run through a few highlights.
Again, you can refer to the details in our deck and earnings release. Our comparisons are to full year 2021. Full year net revenues were RMB 13.5 billion, representing a year-over-year growth at 9%. Our B2B segment revenue grew 10% to RMB 13.1 billion. This result was achieved despite all the disruptions caused by the lockdowns across the country during the year. Our B2C segment revenue decreased 16% to RMB 442 million. Our top-line growth was not that satisfactory, we are pleased to report that we have achieved gross segment profit growth at 35%, which is four times of the revenue growth rate. As a result of the combined gross segment margin was 6.2%, up from 5% a year ago.
B2B gross segment margin was 5.7%, up from 4.3%, while our B2C segments was 21.8%, up from 20.9%. For full year 2022, total operating expenses decreased to 4.8% to RMB 1.2 billion. As a percentage of net revenue, total operating expenses was 8.9%, down from 10.2% last year. Fulfillment expenses accounted for 3% of net revenues this year, as comparable to 2.9% last year. Excluding the share-based compensation and selling and marketing expenses as a percentage of net revenue reduced to 3% this year from 3.7% last year. G&A expenses account for 0.9% net revenue this year, down from 1.1%.
The technology expenses account for 0.9% of net revenue this year as compared to 1.3% last year. As a percentage of net revenues, Non-GAAP loss from operations for the year decreased to 1.6% this year from 4% last year. Non-GAAP net loss attributable to ordinary shareholders as a percentage of net revenues decreased to 1.5% this year from 4.2% last year. We narrowed our loss amount by more than 50% this year versus last year, and reached profitability in Non-GAAP operating level in the month of December. We are confident that our strong technology capability will continue to enable us to build scale, improve efficiency, and deliver a profit of profitability, maximizing values for our shareholders.
Please refer to slide 23 to 30 of the appendix section for selected financial statements. A quick note on our cash position. As of December 31st, 2022, we had cash and cash equivalents, received cash and a short-term investment of RMB 923 million. This concludes our prepared remarks. Thank you. Operator, we are now ready to begin our Q&A session.
Thank you. We will now begin the question and answer session. To ask a question, you may press star then one on your touchtone phone. If you are using a speakerphone, we ask that you please pick up your handset before pressing the keys. To withdraw your question, please press star then two. Today's first question comes from Xipeng Feng with CICC. Please go ahead.
Hi, this is Xipeng from CICC, thank you for taking my questions and congratulations on the company progress. Well, I have two questions, the first one is: After the company achieved breakeven in last December, what is the specific profit expectation for 2023? Post-pandemic era, what are favorable changes for your company, and how will you respond and take on social responsibility? These are my questions. Thanks.
Thank you, Xipeng. I'll take on your first question. Yes, thank you for that question. Indeed, we achieved profitability in December 2023 and 2022. Moving into 2023, the management is very much optimistic about the prospect of us continuing to make profits. If you look back years, we grew the company from less than RMB 1 billion to today, RMB 13.5 billion in revenue. Mind you, our margin has been growing faster than revenue. In the meantime, we are doing a great job in improving our operational efficiency.
If you look into the few buckets of the OpEx, you know, be it the cost to fulfill our orders, be it the sales cost, the technology expenses, the G&A, it's all trending much better. Last year we trimmed 15.5% of our operations compared to the revenue percentage. In all those data, all those data points, you know, give us a lot of optimism moving into 2023. Thank you, Shipeng.
Let me take the same question for Xipeng. I've seen that post-COVID, the demand for health and well-being products is picking up. We saw that more consumers are going to drugstores, which are our customers, to buy their medicine and other health products. We expect an increase in sales for our business. That's one. The other is that during the pandemic, the Chinese government has seen the value of internet to help hospitals and drugstores to reach customers and to help reduce cross-infection and to relieve the shortage
Of hospitals, scarce resources, and also to improve availability of medication on patients in remote areas. As we can see that, during the past, you know, probably a year or so, the CFDA has launched a series of new policies to promote online health. Also the pandemic has influenced the consumer to move to online, and those customers remain to enjoy the benefit and convenience of online service offers even after the pandemic. The total number of users increased. All those changes present tremendous opportunities for us, and we also need to take the opportunity and take on the social responsibility to align with our government to reach the Healthy China 2030 goal. Those are my answers.
Okay. Thank you for your answers, it's very clear. Thanks for the sharing, congratulations again on the company's progress.
Thank you.
Thank you. Our next question today comes from Steven Lee, an individual investor. Please go ahead.
Hello? Hello.
Hi. Hi, Steve.
This is Steve. Thanks for sharing your Q4 results. It was a fantastic season. I have two questions. Firstly, I would like to know what will be the company's operational focus going forward. Secondly, as the company's second consecutive quarter for generating positive operating cash flow, how do you plan to keep this trend? How's company's cash position now?
Yeah. Thank you, Steve. With regards to the question of operational focus, I think I briefly mentioned in my script, you know, essentially, we did a lot of soul-searching in 2022. The organization had some realignment on the strategic focuses operationally. Those are really value creation. We've got to evaluate the businesses on the merit of how much value it can create to our upstream and downstream customers. The second focus will be being customer-centric. As in the past, we were more or less more focused on internal metrics rather than the metrics that, you know, drive the organization towards creating value for customers.
Also the third focus is really to strengthen our supply base. In 2022, we kind of managed to restructure the business. We give up some of the businesses with really no value. We really realigned all the, let's say, weekly business review metrics towards customers instead of our internal metrics like revenue and margin. You know, obviously, we worked really hard towards the suppliers. Although we have built some good relationships, they're not strategic enough, and we're making excellent progress with our digital technical products. All the suppliers we have been talking to are delighted. You know, all of those focuses will really create the following benefits, we believe.
One being the sustained revenue and margin growth and the improved operational efficiency. We should expect our OpEx continue to improve. All those results will really impact the bottom line, which is profitability.
Yeah. On the cash flow, we are very pleased to see that we have achieved two consecutive quarters for positive operating cash flow. We are very confident that we'll be able to keep this good trend as we are very much close to profitability, and we have been operating with very high efficiency. For example, our accounts payable days is around 45 days, and our inventory days is about 30 days. While we further build up our business scale, we will be able to negotiate better trading terms with suppliers. In terms of cash position or cash and cash equivalents and receive cash and short-term investment, as of December year-end, amounted to RMB 923 billion. We believe that we have sufficient cash reserve to support our business expansion. Steve, hope we have answered your questions.
Yes. Thank you both for the sharing.
Thank you. Our next question today comes from Tom Craig at Cornerstone Investment. Please go ahead.
Hello, this is Tom from Cornerstone. Congratulations on your performance last quarter. I have two questions. The first one is, what are the main factors driving the sustained improvement of the B2B growth margin? Is this improvement sustainable? The second one is, the company's operating expense ratio has been consistently decreasing. What is the main reason for this trend? Can it continue to decrease in the future? Thank you.
Okay, Tom, this is Harvey. I'll take your first question regarding the margin of our B2B business. First of all, you know, we are a technology company, I would like to thanks to my technology colleagues for their systems help us to drive our efficiency, including our dynamic inventory management system, which help us to get the best cost in each of our warehouse so we can do dynamic transit among all these warehouse to better serve our customer and also get the best profit. The other very good system called PIS, that is our price intelligence system. It help us to optimize our price real-time and get a good balance on our profit, as well as our customer experience on price.
All these tools, you know, really help us to get a much better profit. Besides the technology and tools, I think even more important is our relationship with the pharmaceutical companies. To further reduce our procurement costs, we direct source from various pharmaceutical companies to lower the cost of product. We are now sourced from over 500 global and domestic pharmaceutical companies. We will continue to deepen our strategic relationship with these companies. Just for everyone's information, in the past two months in this year, I have personally visit over 50 pharmaceutical companies. We all have a very deep discussion on post-COVID, you know, the environment, the customer behavior change.
They all agree to tighten our direct relationship and to find a strategic way to better serve the patients and customers in a post-COVID period. We definitely expect the momentum to continue. Furthermore, with the increase of demand of our customer, with the volume growth, we will definitely see a more scalability in our business and which we are translating into a better profit in our business. Thank you.
Tom, if I heard your question correctly, it's about OpEx, right? What is driving the OpEx down and can it sustain? I wanna answer the question from the second part. You know, can it sustain? Absolutely. We're very confident of that, and we believe there is still much room for our OpEx to improve. You know, the short answer to what drives down the OpEx, the short answer is really our investment into technology. You know, we advocate digitization and we must demonstrate, you know, ourselves being digital first.
If you know, in a conference room today or anywhere or if you're traveling, you know, in some remote areas, you know, with a mobile phone, we actually, you know, exactly know what happens on the day in terms of sales. Not only do we know, you know, the overall company's sales and we know precisely what happens, let's say in Northeast China, in East China, in Northwest China, and in what customer segment, in what categories, in even some SKUs. Knowing all that, you know, it will give us a huge advantage in decision making. Each morning, you know, we have over 1,000 people being the ground sales.
Each morning, those ground sales people will be assigned a list of tasks for today's work. That assignment is not done by the manager. It's actually by the system. Being digital has a lot of advantages. Now, I'm sure, moving into the future, with the new technologies like ChatGPT available, there are more areas we can work on to be more efficient. As we speak, we have a few projects going on and we're experimenting and see how it can further reduce our OpEx. The other factor that contributed to the driving down of the OpEx is really we spent money wisely, and we have to grow. Once our scale grows, obviously, we can scale down the operating cost.
Of course, you know, in conclusion, we still have a lot of confidence to improve a lot more into the future. Thank you.
Thank you. I'm looking forward to the performance next quarter. Thank you.
Thank you. Our next question today comes from Francis Young at BSV Capital. Please go ahead.
Thank you operator. This is Francis from BSV Capital. Congratulations again on the great performance. I've got two questions. The first one is the percentage of non-GAAP operation loss to net revenue has significantly narrowed. What's the main reason for this trend, and how does the company plan to maintain this trend? My second question is, does the company have any new technological developments in recent times? I'd love to hear you share about it. Thanks.
Yeah. On, on the non-GAAP operating loss in fiscal year 2022, our non-GAAP operating loss narrowed to 1.6% of net revenue as compared to 4% in last year. The fourth quarter non-GAAP operating loss was less than 1% of net revenue, and we reached profitability at non-GAAP operating level in the month of December. As just two of my colleagues explained the market expansion and our efficiency on expense, I would like to highlight this narrowing of non-GAAP operating loss mainly attributable to two key drivers. The first, with the customer network we have built up throughout the years, we have been able to sell high margin products and improve the quality of our revenue mix.
We have focused more on profitable and healthy revenue expansion to improve our margin profile. As you can see, we have delivered 35% growth rate in gross margin, which was four times of our revenue growth rate. Overall gross margin has improved from 5% to 6.2%. The second key driver is on technology. We've been assisted with our home development tech solutions. We have been able to streamline our operations to significantly improve our operating efficiency. We have achieved our revenue growth with much less expense investment. As our CEO just shared with you that our spending has been more disciplined. We will continue to work hard on these key two drivers together with the scale build-up to reach profitability.
Let me take the same question from Francis. Let me take the same question from Francis. About our technology investment. We truly believe that technology forms our core competence. We have invested heavily and will continue to invest. Let me just give you a few examples on where we what we have done. First is that we have continued to improve our supply chain. For example, in the past we have, you know, seven fulfillment centers. In China it's very expensive and costly to build the fulfillment centers. We formed so-called partnering FCs. You know, we partner with, you know, some of our suppliers, vendors, you know, to form new, we call it the FC-FC.
We made tremendous progress. This is not what we got. In this year we probably expect another 10 new, we call it partnering fulfillment centers to build up. That will help us to deliver more timely to our customers. We also build a transshipment model to optimize transshipment in between FC. Recently we are applying AIGC to create health content in short videos and text. Some videos created a lot of views. For example, one short video, less than one minute, resulted in more than 590,000 views. These are completely created by AIGC, and we use digital human to talk about health advices.
Along these lines, you know, including the recent ChatGPT development, you know, we are also, we have a group to try to apply ChatGPT to create health assistance to our users. You know, we're really, you know, trying to invest in technology to advance our smart supply chain, to create a better customer experience.
Okay, thank you. Yes, certainly. It was very clear and the artificial intelligence integration sound very exciting. We look forward to hearing more.
Thank you.
Thank you. Our next question today comes from Stephanie Nour with Civic Investments. Please go ahead.
Good evening. This is Stephanie from Civic Investments. Congratulations on your growing revenues. I have two questions. The first one is: What are the company's plans for its OEM products in the future? The second question is, what's the current progress of the company's privatization? Thank you.
Hi, Stephanie. This is Harvey. I'll take your question regarding our OEM, and actually we call it private label.
We have, I think last quarter, when I it's 9 SKUs. Now we have launched 25 SKUs of our private label. All of these 25 SKUs have been well accepted by our pharmacy customers. You know, in those big transport, private label products take about 30%-40% of their margin. While our B2B customers, those individual stores or small chains, they are not able to have their own brand. We put the two private label brand, Guangzhao and Huangjia Rongyao, for different type of customers. We offer this private label to help them to compete with those big ones in this area. There are also about over 100 SKUs in our pipeline.
We expect to see a very fast increasing trend, in this project. Thank you.
Yeah. On the privatization, we understand that the process of the privatization is still ongoing, and the independent committee is working with the buyer group on the privatization proposal. The company shall make all necessary public announcement according to SEC rules. I would suggest that you stay tuned on the announcement if there's any to be made by the company. Thank you.
Thank you. Congratulations again on the great performance of the company.
Thanks.
Thank you. Thank you. Our next question today comes from Adam Frank at Grace Capital. Please go ahead.
Congratulations on excellent performance last quarter. I'm Adam Frank from Grace Capital. I've got two questions. First, does the company have any new business model innovations? The second is, what efforts are company making to improve customer experience? Yes, that's two questions. Thank you.
Adam, very good question. Actually, regarding the new model, we are actually piloting our new model almost every day, every week. Of course, you know, some of them fail. There are also some initiative, you know, has a very good result. For example, like our One Health program, we have 12,000 pharmacies and millions of patients they serve, you know, in this One Health program. Pharmaceutical companies are leveraging this One Health platform to perform various digital marketing, including the coverage of new terminal, new pharmacies, and especially expansion to those remote area and lower tier cities. Also to do patient education, to DOT, duration of treatment, et cetera, with this One Health platform.
This new B2C model has been well accepted by our many pharmaceutical partners. The other example probably, I just mentioned about private label program, you know. It's in a very good trend, well on track. Our pharmaceutical partners, not only, direct source, we direct source from them, also some of our pharmaceutical strategic partners, they are also, OEM for us. All of these, initiatives, you know, is part of our DNA. We will continue to bring more initiatives and to, especially in this, post-COVID, seasons. I think every quarter you should be able to see more and more initiatives, in our announcements. Thank you.
Uh, let me take the question on, uh, our efforts in improving customer experience. Uh, yeah, in my prior answer, I mentioned about, uh, I talked about hundred FC. Also, I mentioned about my shipments in between FC. Uh, these are in fact, uh, a tremendous, uh, improvement for, uh, customer experience because, you know, we have more fulfillment centers and we, we also ship more products, uh, try and ship more products into, uh, uh, fulfillment centers, uh, closer to customers. All this effort will help to shorten the time, uh, for the whole delivery. Uh, right now, uh, Jimmy mentioned that, uh, we are serving eight hundred and ninety cities and counties in within twenty-four hours. So this is a tremendous, uh, improvement in customer experience as well as, uh, for reducing the product damages on the road.
Another example on customer experience is assortment management. In the past we just managed nationwide assortment. Now we drill down one more level. We managed the demand of assortment for each fulfillment center from meeting the demand of local customers. That will help in turn increase our customers' wallet share. I just mentioned those two examples.
Yeah, thank you for your answer. It's very clear. Yeah.
Ladies and gentlemen, this concludes today's question and answer session. In closing, on behalf of the entire 111 management team, we'd like to thank you for your interest and participation in today's call. If you require any further information or have any interest in visiting 111's in Shanghai, China, please let the company know. Thank you for joining the call today. This concludes the call. You may now disconnect your lines. Thank you.