Zentalis Pharmaceuticals, Inc. (ZNTL)

NASDAQ: ZNTL · Real-Time Price · USD
4.090
-0.190 (-4.44%)
At close: May 14, 2026, 4:00 PM EDT
4.050
-0.040 (-0.98%)
After-hours: May 14, 2026, 7:58 PM EDT
Market Cap291.15M +187.8%
Revenue (ttm)n/a
Net Income-124.13M
EPS-1.74
Shares Out 71.19M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume2,593,579
Open4.320
Previous Close4.280
Day's Range3.915 - 4.390
52-Week Range1.130 - 6.950
Beta2.00
AnalystsBuy
Price Target6.60 (+61.37%)
Earnings DateMay 12, 2026

About ZNTL

Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers in the United States. It develops azenosertib, which is in a Phase 3 clinical trial for the treatment of ovarian cancer and other tumor types. The company also develops ZN-c3-001, a phase 1 study that evaluated azenosertib monotherapy in solid tumors; and MAMMOTH (ZN-c3-006) is a Phase 1/2 clinical trial of azenosertib in patients with PARP-inhibitor resistant ovarian ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 3, 2020
Employees 106
Stock Exchange NASDAQ
Ticker Symbol ZNTL
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 5 analysts, the average rating for ZNTL stock is "Buy." The 12-month stock price target is $6.6, which is an increase of 61.37% from the latest price.

Price Target
$6.6
(61.37% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

SAN DIEGO, May 13, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhibi...

1 day ago - GlobeNewsWire

Zentalis Pharmaceuticals Reports First Quarter 2026 Financial Results and Clinical Progress

400mg QD 5:2 selected as azenosertib monotherapy pivotal study dose based on favorable benefit-risk profile in DENALI Part 2a, supporting advancement in registration-intended trials DENALI Phase 2 tri...

2 days ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces First Patient Dosed in ASPENOVA Phase 3 Trial of Azenosertib in Patients with Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

Global Phase 3, randomized, controlled trial comparing azenosertib to standard-of-care chemotherapy now enrolling ASPENOVA designed as confirmatory study to support DENALI Phase 2 accelerated approval...

9 days ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

SAN DIEGO, May 01, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhibi...

13 days ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Abstract Acceptance at ASCO 2026 Featuring Azenosertib in Combination with Paclitaxel for Platinum-Resistant Ovarian Cancer

Results from Part 1 of the Phase 1b MUIR trial to be presented at annual meeting in June Results from Part 1 of the Phase 1b MUIR trial to be presented at annual meeting in June

23 days ago - GlobeNewsWire

Zentalis to present azenosertib preclinical data in TNBC at AACR meeting

Zentalis (ZNTL) announced data from two posters being presented at the 2026 American Association for Cancer Research Annual Meeting, taking place April 17-22, 2026, in San Diego, CA. The data…

27 days ago - TheFly

Zentalis Pharmaceuticals To Present Azenosertib Preclinical Data in Triple-Negative Breast Cancer and Real-World Analysis of Unmet Need in Cyclin E1-Positive Ovarian Cancer at AACR 2026

SAN DIEGO, April 17, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

27 days ago - GlobeNewsWire

Zentalis price target raised to $10 from $6 at Guggenheim

Guggenheim raised the firm’s price target on Zentalis (ZNTL) to $10 from $6 and keeps a Buy rating on the shares, citing increased probability of success assumptions in platinum-resistant ovarian…

4 weeks ago - TheFly

Zentalis Pharmaceuticals Announces 400mg QD 5:2 Azenosertib Monotherapy as the Pivotal Study Dose in Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

Planned interim analysis from DENALI Part 2a showed a clearly differentiated response rate at 400mg QD 5:2 over 300mg QD 5:2 and comparable safety profiles between the two dose groups Azenosertib ther...

5 weeks ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

SAN DIEGO, April 01, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

6 weeks ago - GlobeNewsWire

Zentalis Pharmaceuticals Reports Full Year 2025 Financial Results and Operational Updates

On track for DENALI Part 2a dose confirmation in 1H 2026 DENALI Part 2 trial topline readout expected by year end 2026; potential to support accelerated approval On track to initiate the ASPENOVA Phas...

7 weeks ago - GlobeNewsWire

Zentalis Pharmaceuticals to Present Two Posters at the American Association for Cancer Research (AACR) Annual Meeting 2026

SAN DIEGO, March 17, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

2 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

Azenosertib is advancing in platinum-resistant ovarian cancer with ongoing DENALI and ASPENOVA trials, targeting cyclin E1-positive patients and aiming for accelerated and full approval. The MIRROR study will explore earlier-line combinations, while regulatory and operational milestones are on track.

2 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

Azenosertib is advancing in late-stage trials for PROC patients with high Cyclin E1 expression, targeting a 21,500-patient market in the US, EU4, and UK. The DENALI and ASPENOVA trials are on track, with consistent efficacy, manageable safety, and regulatory alignment for accelerated approval.

2 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

Leadership is advancing azenosertib as a first oral, non-chemo option for PROC, with pivotal DENALI and ASPENOVA trials underway. The drug targets Cyclin E1 positive patients, offering improved quality of life and manageable safety, with regulatory alignment for accelerated and full approval.

2 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Guggenheim Securities Emerging Outlook: Biotech Summit 2026

Azenosertib is advancing through pivotal trials for platinum-resistant ovarian cancer with high cyclin E1, using a biomarker-driven approach and adaptive trial designs to accelerate approval. The drug shows a favorable safety profile and differentiation from existing therapies, with future plans for combinations and potential expansion into other indications.

3 months ago - Transcripts

Zentalis Pharmaceuticals to Participate in Upcoming Investor Conference

SAN DIEGO, Feb. 03, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhib...

3 months ago - GlobeNewsWire

Zentalis provides update, key milestones in 2025, expectations for 2026

Zentalis (ZNTL) Pharmaceuticals provided a corporate update and highlighted key milestones and expected momentum in the azenosertib development program for 2026. 2025 Accomplishments: Completed enroll...

4 months ago - TheFly

Zentalis Pharmaceuticals Provides Corporate Update and Highlights Key Milestones and Expected Momentum in the Azenosertib Development Program for 2026

Completed enrollment in DENALI Part 2a; dose confirmation expected in 1H 2026 DENALI Part 2 trial topline readout expected by year end 2026; potential to support accelerated approval Initiation of the...

4 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Stifel 2025 Healthcare Conference

Azenosertib demonstrates strong efficacy and safety in Cyclin E1-positive PROC, with a phase two trial underway and a phase three confirmatory study planned for 2026. The companion diagnostic is ready, and robust site activation supports global enrollment.

6 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Azenosertib is advancing as a differentiated, oral therapy for platinum-resistant ovarian cancer, with strong response rates and a favorable safety profile. The DENALI trial is on track for top-line data by end of 2026, and combination strategies are being explored for broader impact.

6 months ago - Transcripts

Zentalis price target lowered to $4 from $8 at Morgan Stanley

Morgan Stanley analyst Michael Ulz lowered the firm’s price target on Zentalis (ZNTL) to $4 from $8 and keeps an Equal Weight rating on the shares after the company reported…

6 months ago - TheFly

Zentalis Pharmaceuticals Reports Third Quarter 2025 Financial Results and Operational Progress

DENALI Phase 2 trial evaluating azenosertib in patients with Cyclin E1-positive PROC remains on track with topline data anticipated by year end 2026, with the potential to support an accelerated appro...

6 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Four Azenosertib Posters Presentations at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Presentations feature data from first-in-human Phase 1 study including Cyclin E1 biomarker findings, supporting late-stage development of azenosertib Presentations feature data from first-in-human Pha...

7 months ago - GlobeNewsWire

Zentalis board member Letai frontrunner to lead NCI, STAT reports

Anthony Letai, a cancer researcher and oncologist at the Dana-Farber Cancer Institute and Harvard University and a member of the scientific advisory board at Zentalis (ZNTL), has emerged as a…

8 months ago - TheFly