| 1 | PRAX | Praxis Precision Medicines, Inc. | 5.03% |
| 2 | PTCT | PTC Therapeutics, Inc. | 4.75% |
| 3 | SRRK | Scholar Rock Holding Corporation | 4.44% |
| 4 | BIIB | Biogen Inc. | 4.33% |
| 5 | ARGX | argenx SE | 4.25% |
| 6 | AXSM | Axsome Therapeutics, Inc. | 4.15% |
| 7 | CPRX | Catalyst Pharmaceuticals, Inc. | 3.90% |
| 8 | XENE | Xenon Pharmaceuticals Inc. | 3.64% |
| 9 | KRX: 326030 | SK Biopharmaceuticals Co., Ltd. | 3.61% |
| 10 | CNTA | Centessa Pharmaceuticals plc | 3.58% |
| 11 | DYN | Dyne Therapeutics, Inc. | 3.50% |
| 12 | DNLI | Denali Therapeutics Inc. | 3.43% |
| 13 | SUPN | Supernus Pharmaceuticals, Inc. | 3.42% |
| 14 | NBIX | Neurocrine Biosciences, Inc. | 3.42% |
| 15 | ALKS | Alkermes plc | 3.32% |
| 16 | ACAD | ACADIA Pharmaceuticals Inc. | 3.24% |
| 17 | AVDL | Avadel Pharmaceuticals plc | 3.08% |
| 18 | HLBBF | H. Lundbeck A/S | 2.71% |
| 19 | EWTX | Edgewise Therapeutics, Inc. | 2.56% |
| 20 | SRPT | Sarepta Therapeutics, Inc. | 2.47% |
| 21 | ASX: NEU | Neuren Pharmaceuticals Limited | 1.87% |
| 22 | AXGN | Axogen, Inc. | 1.78% |
| 23 | STO: BIOA.B | BioArctic AB (publ) | 1.73% |
| 24 | DNTH | Dianthus Therapeutics, Inc. | 1.45% |
| 25 | TSHA | Taysha Gene Therapies, Inc. | 1.39% |
| View IBRN holdings |