Ionis Pharmaceuticals, Inc. (BMV:IONS)

Ionis Pharmaceuticals Ratios and Metrics

Market cap in millions MXN. Fiscal year is January - December.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Sep 23, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Market Capitalization	236,007	115,024	122,707	104,655	88,091	157,309
Market Cap Growth	112.74%	-6.26%	17.25%	18.80%	-44.00%	-1.85%
Enterprise Value	232,846	104,685	118,191	90,329	73,932	131,633
Last Close Price	1150.00	743.00	737.51	877.25	621.80	1099.50
PS Ratio	13.31	7.83	9.22	9.13	5.30	10.84
PB Ratio	20.82	9.38	18.77	9.37	5.57	10.64
P/TBV Ratio	20.82	9.38	18.77	9.37	5.57	11.05
P/FCF Ratio	-	-	-	-	228.03	10240.42
P/OCF Ratio	-	-	-	-	139.52	220.26
EV/Sales Ratio	14.01	7.13	8.88	7.88	4.45	9.07
EV/FCF Ratio	-41.94	-	-	-	191.38	8569.00
Debt / Equity Ratio	3.33	3.33	5.09	2.39	1.62	1.26
Debt / FCF Ratio	-	-	-	-	66.39	1217.15
Asset Turnover	0.32	0.24	0.28	0.23	0.32	0.26
Inventory Turnover	45.90	91.49	61.67	36.18	27.98	0.60
Quick Ratio	2.51	7.74	5.44	6.49	9.13	3.30
Current Ratio	2.79	8.47	5.90	7.07	9.75	3.56
Return on Equity (ROE)	-40.04%	-93.10%	-76.34%	-40.12%	-3.77%	-39.52%
Return on Assets (ROA)	-5.68%	-9.91%	-7.55%	-9.96%	-0.75%	-3.82%
Return on Invested Capital (ROIC)	-73.48%	-364.50%	-	-	-	-
Return on Capital Employed (ROCE)	-13.10%	-17.60%	-13.10%	-18.50%	-1.30%	-9.60%
Earnings Yield	-1.99%	-8.22%	-5.05%	-5.03%	-0.67%	-5.62%
FCF Yield	-2.35%	-9.89%	-4.57%	-5.41%	0.44%	0.01%
Buyback Yield / Dilution	-8.89%	-4.42%	-0.95%	-0.59%	-1.01%	8.85%

Source: S&P Global Market Intelligence. Standard template. Financial Sources.