Ionis Pharmaceuticals, Inc. (BMV:IONS)

Mexico flag Mexico · Delayed Price · Currency is MXN
1,150.00
+50.00 (4.55%)
At close: Sep 24, 2025
Market Cap152.78B +22.9%
Revenue (ttm)19.08B +47.5%
Net Income-5.89B
EPS-36.49
Shares Out n/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume8
Open1,150.00
Previous Close1,100.00
Day's Range1,150.00 - 1,150.00
52-Week Range619.00 - 1,180.00
Betan/a
Analystsn/a
Price Targetn/a
Earnings DateJul 29, 2026

About Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also ... [Read more]

Industry Biological Products, Except Diagnostic Substances
Founded 1989
Employees 1,402
Stock Exchange Mexican Stock Exchange
Ticker Symbol IONS

Financial Performance

In 2025, Ionis Pharmaceuticals's revenue was $943.71 million, an increase of 33.83% compared to the previous year's $705.14 million. Losses were -$381.39 million, -15.97% less than in 2024.

Financial numbers in USD Financial Statements

News

Ionis Pharmaceuticals price target lowered to $89 from $106 at Guggenheim

Guggenheim lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $89 from $106 and keeps a Buy rating on the shares. The firm is revising some of its estimates…

18 hours ago - TheFly

Wolfe cuts Ionis Pharma to Peer Perform after disappointing trial data

Wolfe Research downgraded Ionis Pharmaceuticals (IONS) to Peer Perform from Outperform. Two trial disappointments – TTR and tau – nullified most of the firm’s prior bull thesis, while its remaining…

6 days ago - TheFly

Ionis Pharmaceuticals downgraded to Peer Perform from Outperform at Wolfe Research

Wolfe Research downgraded Ionis Pharmaceuticals (IONS) to Peer Perform from Outperform.

6 days ago - TheFly

Ionis Pharmaceuticals, Inc. (IONS) Faces Investor Scrutiny After Surprise Trial Failure Drives Stock Down 23% – HBSS

SAN FRANCISCO, July 15, 2026 (GLOBE NEWSWIRE) -- Investors in Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) saw the price of their shares plunge $20.19 (-23%) on July 9, 2026 after the commercial stage b...

6 days ago - GlobeNewsWire

Ionis to hold second quarter 2026 financial results webcast

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that it will host a live webcast on Wednesday, July 29 at 8:30 a.m. Eastern Time to discuss its second qua...

6 days ago - Business Wire

Ionis says Biogen presents Phase 2 CELIA data at AAIC

Ionis Pharmaceuticals (IONS) announced that its partner, Biogen (BIIB), shared data from the Phase 2 CELIA study evaluating diranersen, an investigational antisense oligonucleotide therapy targeting t...

7 days ago - TheFly

Ionis Partner Biogen Presents Phase 2 CELIA Data at AAIC Demonstrating Meaningful Clinical Outcomes and Robust Tau Reduction with Diranersen in Early Alzheimer's Disease

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that its partner, Biogen, shared data from the Phase 2 CELIA study evaluating diranersen, an investigation...

7 days ago - Business Wire

Alnylam price target raised to $485 from $470 at H.C. Wainwright

H.C. Wainwright raised the firm’s price target on Alnylam (ALNY) to $485 from $470 and keeps a Buy rating on the shares after AstraZeneca (AZN) and Ionis Pharmaceuticals (IONS) recently…

8 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $85 from $100 at RBC Capital

RBC Capital analyst Luca Issi lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $85 from $100 and keeps an Outperform rating on the shares. The company has an…

8 days ago - TheFly

Ionis Pharmaceuticals doses first participant in Phase 1-2 ASCEND study

Ionis Pharmaceuticals (IONS) announced that the first participant has been dosed in the Phase 1-2 ASCEND study of ION337, an investigational RNA-targeted medicine for people living with Dravet syndrom...

8 days ago - TheFly

Ionis doses first participant in Phase 1-2 ASCEND study of ION337 in Dravet syndrome

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the first participant has been dosed in the Phase 1-2 ASCEND study of ION337, an investigational RNA-...

8 days ago - Business Wire

H.C. Wainwright trims Ionis price target, says trial failure reaction ‘overdone’

H.C. Wainwright analyst Mitchell Kapoor lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $125 from $130 and keeps a Buy rating on the shares. The firm has cut…

11 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $110 from $130 at Morgan Stanley

Morgan Stanley lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $110 from $130 and keeps an Overweight rating on the shares.

11 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $95 from $110 at Canaccord

Canaccord analyst Gary Nachman lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $95 from $110 and keeps a Buy rating on the shares. The firm and its partner…

11 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $90 from $115 at Barclays

Barclays lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $90 from $115 and keeps an Overweight rating on the shares after the company and partner AstraZeneca (AZN) announced…

11 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $100 from $115 at Citi

Citi analyst Eric Joseph lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $100 from $115 and keeps a Buy rating on the shares. The firm is updating its…

11 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $90 from $113 at Jefferies

Jefferies analyst Akash Tewari lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $90 from $113 and keeps a Buy rating on the shares after the CARDIO-TTRansform Phase 3…

12 days ago - TheFly

Ionis Pharmaceuticals price target lowered to $86 from $105 at Needham

Needham analyst Joseph Stringer lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $86 from $105 and keeps a Buy rating on the shares after the company and partner…

12 days ago - TheFly

AstraZeneca Stock and Partner Ionis Sink After Trial Failure. Alnylam Soars.

AstraZeneca and California-based biotech Ionis Pharmaceuticals announce a late-stage trial failure for their gene silencing drug, Wainua.

12 days ago - Barrons

Major drugmaker loses $27 billion in market value after failed trial

Two companies announced on Thursday that the heart disease drug they had been developing failed its Phase III trial.

12 days ago - Market Watch

AstraZeneca-Ionis drug fails to meet main goal in late-stage heart disease trial

AstraZeneca said ​on Thursday ‌that its drug ​Wainua, ​made in partnership ⁠with ​Ionis , ​failed to meet the ​main ​goal of reducing ‌cardiovascular ⁠deaths and recurring heart ​problems ​in ⁠a late-...

13 days ago - Reuters

Update on CARDIO-TTRansform Phase 3 trial of eplontersen in adults with transthyretin-mediated amyloid cardiomyopathy

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and partner AstraZeneca today announced that the CARDIO-TTRansform Phase 3 trial for eplontersen in patients with transthy...

13 days ago - Business Wire

Ionis completes enrollment in pivotal cohort of the Phase 3 REVEAL study evaluating obudanersen in Angelman syndrome

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that it has completed enrollment in the pivotal cohort (Cohort 1) of the global Phase 3 REVEAL study evalu...

15 days ago - Business Wire

Ionis announces license agreement with Recordati for zilganersen in Alexander disease (AxD) in all countries outside the U.S.

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that it has entered into a license agreement with Recordati (“Recordati”), under which Recordati obtained ...

26 days ago - Business Wire

Ionis Pharmaceuticals Transcript: FDA announcement

TRYNGOLZA received FDA approval as the first therapy to reduce triglycerides and acute pancreatitis risk in adults with sHTG, supported by robust phase III data showing up to 72% triglyceride reduction and 91% reduction in pancreatitis events. The launch will focus on high-risk patients, with broad payer access and strong support programs expected to drive adoption.

27 days ago - Transcripts