Ionis Pharmaceuticals, Inc. (FRA:ISI)

Ionis Pharmaceuticals Statistics

Total Valuation

FRA:ISI has a market cap or net worth of EUR 11.42 billion. The enterprise value is 11.27 billion.

Market Cap	11.42B
Enterprise Value	11.27B

Important Dates

The next estimated earnings date is Wednesday, February 18, 2026.

Earnings Date	Feb 18, 2026
Ex-Dividend Date	n/a

Share Statistics

Current Share Class	161.97M
Shares Outstanding	n/a
Shares Change (YoY)	+8.89%
Shares Change (QoQ)	-12.38%
Owned by Insiders (%)	0.74%
Owned by Institutions (%)	102.79%
Float	160.71M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	13.86
PB Ratio	21.69
P/TBV Ratio	21.69
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	-51.56
EV / Sales	13.54
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	-43.67

Financial Position

The company has a current ratio of 2.79, with a Debt / Equity ratio of 3.33.

Current Ratio	2.79
Quick Ratio	2.51
Debt / Equity	3.33
Debt / EBITDA	n/a
Debt / FCF	-6.80
Interest Coverage	-3.07

Financial Efficiency

Return on equity (ROE) is -40.04% and return on invested capital (ROIC) is -6.52%.

Return on Equity (ROE)	-40.04%
Return on Assets (ROA)	-5.68%
Return on Invested Capital (ROIC)	-6.52%
Return on Capital Employed (ROCE)	-13.06%
Revenue Per Employee	770,942
Profits Per Employee	-204,378
Employee Count	1,069
Asset Turnover	0.32
Inventory Turnover	45.90

Taxes

Income Tax	-2.03M
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +110.31% in the last 52 weeks.

Beta (5Y)	n/a
52-Week Price Change	+110.31%
50-Day Moving Average	61.22
200-Day Moving Average	40.44
Relative Strength Index (RSI)	70.25
Average Volume (20 Days)	20

Short Selling Information

Short Interest	n/a
Short Previous Month	n/a
Short % of Shares Out	n/a
Short % of Float	n/a
Short Ratio (days to cover)	4.97

Income Statement

In the last 12 months, FRA:ISI had revenue of EUR 824.14 million and -218.48 million in losses. Loss per share was -1.37.

Revenue	824.14M
Gross Profit	62.82M
Operating Income	-236.98M
Pretax Income	-220.51M
Net Income	-218.48M
EBITDA	-227.39M
EBIT	-236.98M
Loss Per Share	-1.37

Balance Sheet

The company has 1.91 billion in cash and 1.76 billion in debt, giving a net cash position of 156.78 million.

Cash & Cash Equivalents	1.91B
Total Debt	1.76B
Net Cash	156.78M
Net Cash Per Share	n/a
Equity (Book Value)	526.69M
Book Value Per Share	3.27
Working Capital	1.38B

Cash Flow

In the last 12 months, operating cash flow was -210.53 million and capital expenditures -47.43 million, giving a free cash flow of -257.96 million.

Operating Cash Flow	-210.53M
Capital Expenditures	-47.43M
Free Cash Flow	-257.96M
FCF Per Share	n/a

Margins

Gross margin is 7.62%, with operating and profit margins of -28.75% and -26.51%.

Gross Margin	7.62%
Operating Margin	-28.75%
Pretax Margin	-26.76%
Profit Margin	-26.51%
EBITDA Margin	-27.59%
EBIT Margin	-28.75%
FCF Margin	n/a

Dividends & Yields

FRA:ISI does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-8.89%
Shareholder Yield	-8.89%
Earnings Yield	-1.91%
FCF Yield	-2.26%

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

FRA:ISI has an Altman Z-Score of 1.05 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score	1.05
Piotroski F-Score	4