iShares NASDAQ US Biotechnology UCITS ETF (LON:BTEC)

LON:BTEC Holdings List

As of Jun 12, 2025

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No.	Symbol	Name	% Weight	Shares
1	GILD	Gilead Sciences, Inc.	8.24%	337,362
2	AMGN	Amgen Inc.	8.17%	125,181
3	VRTX	Vertex Pharmaceuticals Incorporated	8.12%	80,377
4	REGN	Regeneron Pharmaceuticals, Inc.	5.93%	51,705
5	AZN	AstraZeneca PLC	4.61%	280,044
6	ALNY	Alnylam Pharmaceuticals, Inc.	4.17%	62,255
7	BIIB	Biogen Inc.	2.05%	70,396
8	ARGX	argenx SE	1.98%	15,394
9	INSM	Insmed Incorporated	1.85%	87,062
10	RPRX	Royalty Pharma plc	1.61%	208,429
11	SMMT	Summit Therapeutics Inc.	1.57%	354,815
12	SNY	Sanofi	1.54%	138,211
13	ILMN	Illumina, Inc.	1.47%	76,188
14	INCY	Incyte Corporation	1.42%	93,089
15	UTHR	United Therapeutics Corporation	1.36%	21,591
16	NBIX	Neurocrine Biosciences, Inc.	1.32%	47,964
17	TEM	Tempus AI, Inc.	1.26%	80,418
18	EXEL	Exelixis, Inc.	1.24%	134,625
19	ONC	BeOne Medicines Ltd.	1.22%	20,131
20	BMRN	BioMarin Pharmaceutical Inc.	1.15%	91,755
21	VTRS	Viatris Inc.	1.15%	574,175
22	MRNA	Moderna, Inc.	1.11%	185,577
23	BNTX	BioNTech SE	1.10%	47,855
24	ASND	Ascendis Pharma A/S	1.09%	29,053
25	MEDP	Medpace Holdings, Inc.	0.98%	14,647
26	BPMC	Blueprint Medicines Corporation	0.87%	30,747
27	ROIV	Roivant Sciences Ltd.	0.86%	343,258
28	RVMD	Revolution Medicines, Inc.	0.81%	89,439
29	BBIO	BridgeBio Pharma, Inc.	0.80%	91,496
30	VRNA	Verona Pharma plc	0.77%	37,913
31	HALO	Halozyme Therapeutics, Inc.	0.71%	59,249
32	JAZZ	Jazz Pharmaceuticals plc	0.71%	29,214
33	MDGL	Madrigal Pharmaceuticals, Inc.	0.69%	10,618
34	GH	Guardant Health, Inc.	0.64%	59,383
35	IONS	Ionis Pharmaceuticals, Inc.	0.60%	76,491
36	AXSM	Axsome Therapeutics, Inc.	0.55%	23,459
37	NUVL	Nuvalent, Inc.	0.54%	31,834
38	ADMA	ADMA Biologics, Inc.	0.54%	113,740
39	ALKS	Alkermes plc	0.53%	78,238
40	PCVX	Vaxcyte, Inc.	0.47%	61,955
41	AKRO	Akero Therapeutics, Inc.	0.45%	38,313
42	KRYS	Krystal Biotech, Inc.	0.43%	13,858
43	PTCT	PTC Therapeutics, Inc.	0.42%	37,951
44	RYTM	Rhythm Pharmaceuticals, Inc.	0.42%	30,421
45	CYTK	Cytokinetics, Incorporated	0.42%	56,971
46	RNA	Avidity Biosciences, Inc.	0.41%	57,837
47	MRUS	Merus N.V.	0.40%	33,251
48	ACLX	Arcellx, Inc.	0.39%	26,441
49	RARE	Ultragenyx Pharmaceutical Inc.	0.38%	44,505
50	ACAD	ACADIA Pharmaceuticals Inc.	0.38%	80,329
51	SRPT	Sarepta Therapeutics, Inc.	0.38%	46,684
52	CRSP	CRISPR Therapeutics AG	0.37%	41,276
53	SWTX	SpringWorks Therapeutics, Inc.	0.37%	36,061
54	PTGX	Protagonist Therapeutics, Inc.	0.37%	29,537
55	SRRK	Scholar Rock Holding Corporation	0.33%	45,557
56	KYMR	Kymera Therapeutics, Inc.	0.33%	31,563
57	LEGN	Legend Biotech Corporation	0.33%	39,341
58	CRNX	Crinetics Pharmaceuticals, Inc.	0.32%	44,767
59	ALVO	Alvotech	0.31%	142,796
60	IMVT	Immunovant, Inc.	0.29%	81,747
61	ZLAB	Zai Lab Limited	0.28%	29,618
62	AMRX	Amneal Pharmaceuticals, Inc.	0.26%	149,442
63	XENE	Xenon Pharmaceuticals Inc.	0.26%	36,259
64	APLS	Apellis Pharmaceuticals, Inc.	0.26%	60,469
65	MIRM	Mirum Pharmaceuticals, Inc.	0.26%	23,709
66	IBRX	ImmunityBio, Inc.	0.25%	353,133
67	n/a	USD - Spendable Cash	0.24%	1,115,036
68	NAMS	NewAmsterdam Pharma Company N.V.	0.24%	52,010
69	LGND	Ligand Pharmaceuticals Incorporated	0.23%	9,332
70	BCRX	BioCryst Pharmaceuticals, Inc.	0.23%	101,892
71	DNLI	Denali Therapeutics Inc.	0.23%	70,396
72	VCEL	Vericel Corporation	0.23%	24,171
73	VCYT	Veracyte, Inc.	0.22%	37,669
74	ARWR	Arrowhead Pharmaceuticals, Inc.	0.22%	61,449
75	RXRX	Recursion Pharmaceuticals, Inc.	0.22%	191,273
76	CGON	CG Oncology, Inc.	0.22%	36,958
77	TWST	Twist Bioscience Corporation	0.21%	28,818
78	n/a	E-MINI HEALTH CARE SECTOR JUN 25	0.21%	7
79	AGIO	Agios Pharmaceuticals, Inc.	0.21%	27,887
80	IDYA	IDEAYA Biosciences, Inc.	0.21%	42,797
81	NVCR	NovoCure Limited	0.21%	52,068
82	APGE	Apogee Therapeutics, Inc.	0.20%	21,916
83	FOLD	Amicus Therapeutics, Inc.	0.20%	148,223
84	HRMY	Harmony Biosciences Holdings, Inc.	0.20%	27,164
85	IRON	Disc Medicine, Inc.	0.19%	16,816
86	SUPN	Supernus Pharmaceuticals, Inc.	0.19%	26,440
87	LON: INDV	Indivior PLC	0.18%	58,781
88	ARQT	Arcutis Biotherapeutics, Inc.	0.17%	57,597
89	DYN	Dyne Therapeutics, Inc.	0.17%	53,565
90	TARS	Tarsus Pharmaceuticals, Inc.	0.17%	18,617
91	JANX	Janux Therapeutics, Inc.	0.16%	28,810
92	ADPT	Adaptive Biotechnologies Corporation	0.16%	69,954
93	BEAM	Beam Therapeutics Inc.	0.16%	40,755
94	EWTX	Edgewise Therapeutics, Inc.	0.16%	45,846
95	VERA	Vera Therapeutics, Inc.	0.15%	31,109
96	SPRY	ARS Pharmaceuticals, Inc.	0.15%	47,770
97	GRAL	GRAIL, Inc.	0.15%	16,192
98	IMCR	Immunocore Holdings plc	0.15%	18,769
99	OCUL	Ocular Therapeutix, Inc.	0.15%	74,438
100	ETNB	89bio, Inc.	0.15%	69,108
101	ANIP	ANI Pharmaceuticals, Inc.	0.15%	10,634
102	TVTX	Travere Therapeutics, Inc.	0.14%	43,263
103	INVA	Innoviva, Inc.	0.14%	29,675
104	GPCR	Structure Therapeutics Inc.	0.14%	28,208
105	AMPH	Amphastar Pharmaceuticals, Inc.	0.14%	23,528
106	DVAX	Dynavax Technologies Corporation	0.14%	59,514
107	CVAC	CureVac N.V.	0.13%	109,104
108	MNKD	MannKind Corporation	0.12%	148,148
109	AUPH	Aurinia Pharmaceuticals Inc.	0.12%	67,528
110	KNSA	Kiniksa Pharmaceuticals International, plc	0.12%	19,890
111	NVAX	Novavax, Inc.	0.12%	76,156
112	TXG	10x Genomics, Inc.	0.12%	51,246
113	WVE	Wave Life Sciences Ltd.	0.12%	74,938
114	CNTA	Centessa Pharmaceuticals plc	0.12%	44,761
115	PCRX	Pacira BioSciences, Inc.	0.12%	21,915
116	n/a	RUSSELL 2000 EMINI CME JUN 25	0.12%	5
117	HROW	Harrow, Inc.	0.12%	17,126
118	GRFS	Grifols, S.A.	0.12%	59,297
119	SYRE	Spyre Therapeutics, Inc.	0.11%	28,522
120	GERN	Geron Corporation	0.10%	301,521
121	GMAB	Genmab A/S	0.10%	20,110
122	ELVN	Enliven Therapeutics, Inc.	0.10%	23,232
123	COLL	Collegium Pharmaceutical, Inc.	0.10%	15,344
124	ABCL	AbCellera Biologics Inc.	0.10%	142,707
125	CRMD	CorMedix Inc.	0.10%	29,612
126	AVDL	Avadel Pharmaceuticals plc	0.10%	46,359
127	ZYME	Zymeworks Inc.	0.10%	33,042
128	SNDX	Syndax Pharmaceuticals, Inc.	0.09%	40,426
129	PRAX	Praxis Precision Medicines, Inc.	0.09%	9,550
130	NRIX	Nurix Therapeutics, Inc.	0.09%	35,925
131	ARDX	Ardelyx, Inc.	0.09%	112,863
132	QURE	uniQure N.V.	0.09%	25,587
133	NTLA	Intellia Therapeutics, Inc.	0.09%	48,996
134	LENZ	LENZ Therapeutics, Inc.	0.09%	13,357
135	n/a	USD - OTHER PAYABLES/RECEIVABLES	0.09%	393,774
136	COGT	Cogent Biosciences, Inc.	0.09%	53,867
137	AVBP	ArriVent BioPharma, Inc.	0.08%	16,340
138	REPL	Replimune Group, Inc.	0.08%	37,934
139	MLYS	Mineralys Therapeutics, Inc.	0.08%	24,130
140	IOVA	Iovance Biotherapeutics, Inc.	0.08%	155,249
141	ANAB	AnaptysBio, Inc.	0.08%	14,884
142	PHAT	Phathom Pharmaceuticals, Inc.	0.08%	34,382
143	VIR	Vir Biotechnology, Inc.	0.08%	65,544
144	AVXL	Anavex Life Sciences Corp.	0.07%	40,817
145	ABUS	Arbutus Biopharma Corporation	0.07%	92,682
146	ORIC	ORIC Pharmaceuticals, Inc.	0.07%	34,259
147	DAWN	Day One Biopharmaceuticals, Inc.	0.07%	48,476
148	XNCR	Xencor, Inc.	0.07%	33,642
149	STOK	Stoke Therapeutics, Inc.	0.07%	26,609
150	XERS	Xeris Biopharma Holdings, Inc.	0.07%	70,567
151	EOLS	Evolus, Inc.	0.07%	30,406
152	KALV	KalVista Pharmaceuticals, Inc.	0.07%	23,644
153	EYPT	EyePoint Pharmaceuticals, Inc.	0.07%	34,864
154	RLAY	Relay Therapeutics, Inc.	0.06%	81,919
155	VERV	Verve Therapeutics, Inc.	0.06%	43,825
156	MNMD	Mind Medicine (MindMed) Inc.	0.06%	36,798
157	HCM	HUTCHMED (China) Limited	0.06%	15,138
158	SANA	Sana Biotechnology, Inc.	0.06%	105,538
159	TNGX	Tango Therapeutics, Inc.	0.06%	52,797
160	FTRE	Fortrea Holdings Inc.	0.06%	42,252
161	CSTL	Castle Biosciences, Inc.	0.06%	13,863
162	TRVI	Trevi Therapeutics, Inc.	0.06%	42,285
163	ALT	Altimmune, Inc.	0.06%	36,406
164	CGEM	Cullinan Therapeutics, Inc.	0.06%	28,967
165	TYRA	Tyra Biosciences, Inc.	0.06%	24,886
166	ARVN	Arvinas, Inc.	0.06%	33,798
167	KURA	Kura Oncology, Inc.	0.06%	38,394
168	TRML	Tourmaline Bio, Inc.	0.06%	12,816
169	RGNX	REGENXBIO Inc.	0.06%	24,936
170	KROS	Keros Therapeutics, Inc.	0.06%	18,604
171	ZVRA	Zevra Therapeutics, Inc.	0.06%	27,051
172	PAHC	Phibro Animal Health Corporation	0.06%	10,217
173	TBPH	Theravance Biopharma, Inc.	0.05%	23,364
174	MGTX	MeiraGTx Holdings plc	0.05%	37,435
175	TSHA	Taysha Gene Therapies, Inc.	0.05%	92,510
176	PSNL	Personalis, Inc.	0.05%	41,727
177	SIGA	SIGA Technologies, Inc.	0.05%	36,268
178	ORKA	Oruka Therapeutics, Inc.	0.05%	17,905
179	URGN	UroGen Pharma Ltd.	0.05%	20,742
180	n/a	USD CASH(Corp Act)	0.05%	226,539
181	AMLX	Amylyx Pharmaceuticals, Inc.	0.05%	40,502
182	AUTL	Autolus Therapeutics plc	0.05%	102,928
183	ERAS	Erasca, Inc.	0.05%	143,703
184	PGEN	Precigen, Inc.	0.05%	144,485
185	RAPP	Rapport Therapeutics, Inc.	0.05%	18,725
186	GLPG	Galapagos NV	0.05%	7,217
187	MESO	Mesoblast Limited	0.04%	16,156
188	RIGL	Rigel Pharmaceuticals, Inc.	0.04%	9,175
189	BCYC	Bicycle Therapeutics plc	0.04%	22,455
190	SAGE	Sage Therapeutics, Inc.	0.04%	29,287
191	SVRA	Savara Inc.	0.04%	81,442
192	ARCT	Arcturus Therapeutics Holdings Inc.	0.04%	13,522
193	MRVI	Maravai LifeSciences Holdings, Inc.	0.04%	73,951
194	SLDB	Solid Biosciences Inc.	0.04%	36,067
195	PACB	Pacific Biosciences of California, Inc.	0.04%	139,603
196	n/a	GBP - Spendable Cash	0.04%	118,737
197	ITOS	iTeos Therapeutics, Inc.	0.04%	16,154
198	RCKT	Rocket Pharmaceuticals, Inc.	0.03%	50,474
199	TERN	Terns Pharmaceuticals, Inc.	0.03%	39,014
200	TRDA	Entrada Therapeutics, Inc.	0.03%	19,336
201	AURA	Aura Biosciences, Inc.	0.03%	22,566
202	TECX	Tectonic Therapeutic, Inc.	0.03%	6,654
203	ALMS	Alumis Inc.	0.03%	46,948
204	ABSI	Absci Corporation	0.03%	51,830
205	ALLO	Allogene Therapeutics, Inc.	0.03%	103,390
206	ATXS	Astria Therapeutics, Inc.	0.03%	25,488
207	OLMA	Olema Pharmaceuticals, Inc.	0.03%	35,093
208	HUMA	Humacyte, Inc.	0.03%	58,854
209	VNDA	Vanda Pharmaceuticals Inc.	0.03%	30,238
210	TKNO	Alpha Teknova, Inc.	0.03%	24,073
211	NGNE	Neurogene Inc.	0.03%	6,712
212	AMRN	Amarin Corporation plc	0.03%	10,213
213	GLUE	Monte Rosa Therapeutics, Inc.	0.03%	27,748
214	AQST	Aquestive Therapeutics, Inc.	0.03%	41,156
215	RNAC	Cartesian Therapeutics, Inc.	0.03%	13,139
216	CMPS	COMPASS Pathways plc	0.03%	29,660
217	PRTA	Prothena Corporation plc	0.03%	26,030
218	ANNX	Annexon, Inc.	0.03%	48,128
219	AVIR	Atea Pharmaceuticals, Inc.	0.03%	39,596
220	LXRX	Lexicon Pharmaceuticals, Inc.	0.03%	178,586
221	CRVS	Corvus Pharmaceuticals, Inc.	0.03%	29,012
222	SLN	Silence Therapeutics plc	0.03%	21,231
223	INZY	Inozyme Pharma, Inc.	0.03%	29,005
224	MXCT	MaxCyte, Inc.	0.03%	50,521
225	FHTX	Foghorn Therapeutics Inc.	0.03%	25,099
226	THRD	Third Harmonic Bio, Inc.	0.02%	20,876
227	n/a	CASH COLLATERAL USD HSBFT	0.02%	110,000
228	ESPR	Esperion Therapeutics, Inc.	0.02%	88,947
229	OMER	Omeros Corporation	0.02%	28,951
230	CDXS	Codexis, Inc.	0.02%	44,918
231	TVGN	Tevogen Bio Holdings Inc.	0.02%	79,029
232	DSGN	Design Therapeutics, Inc.	0.02%	25,562
233	OABI	OmniAb, Inc.	0.02%	58,169
234	ACIU	AC Immune SA	0.02%	47,162
235	FDMT	4D Molecular Therapeutics, Inc.	0.02%	20,883
236	INBX	Inhibrx Biosciences, Inc.	0.02%	6,530
237	CRGX	CARGO Therapeutics, Inc.	0.02%	20,787
238	YMAB	Y-mAbs Therapeutics, Inc.	0.02%	19,856
239	SCPH	scPharmaceuticals Inc.	0.02%	22,609
240	VYGR	Voyager Therapeutics, Inc.	0.02%	24,261
241	PRME	Prime Medicine, Inc.	0.02%	59,334
242	EDIT	Editas Medicine, Inc.	0.02%	38,748
243	LRMR	Larimar Therapeutics, Inc.	0.02%	28,802
244	ALEC	Alector, Inc.	0.02%	50,210
245	FATE	Fate Therapeutics, Inc.	0.02%	51,425
246	ENTA	Enanta Pharmaceuticals, Inc.	0.02%	9,581
247	KYTX	Kyverna Therapeutics, Inc.	0.01%	19,501
248	NMRA	Neumora Therapeutics, Inc.	0.01%	72,934
249	LYEL	Lyell Immunopharma, Inc.	0.01%	6,457
250	LXEO	Lexeo Therapeutics, Inc.	0.01%	14,927
251	NKTX	Nkarta, Inc.	0.01%	31,870
252	CCCC	C4 Therapeutics, Inc.	0.01%	31,880
253	IRWD	Ironwood Pharmaceuticals, Inc.	0.01%	72,075
254	BMEA	Biomea Fusion, Inc.	0.01%	17,796
255	MGNX	MacroGenics, Inc.	0.01%	29,088
256	PLRX	Pliant Therapeutics, Inc.	0.01%	27,481
257	CLYM	Climb Bio, Inc.	0.01%	30,351
258	TCRX	TScan Therapeutics, Inc.	0.01%	22,168
259	PYXS	Pyxis Oncology, Inc.	0.01%	26,854
260	STRO	Sutro Biopharma, Inc.	0.01%	37,224
261	ARTV	Artiva Biotherapeutics, Inc.	0.00%	10,980
262	PEPG	PepGen Inc.	0.00%	14,723
263	MRSN	Mersana Therapeutics, Inc.	0.00%	55,773
264	APLT	Applied Therapeutics, Inc.	0.00%	52,525
265	IGMS	IGM Biosciences, Inc.	0.00%	15,399
266	ACRV	Acrivon Therapeutics, Inc.	0.00%	14,053
267	OKUR	OnKure Therapeutics, Inc.	0.00%	5,707
268	QTTB	Q32 Bio Inc.	0.00%	7,223
269	n/a	EUR - Spendable Cash	0.00%	4,377
270	n/a	OMNIAB INC $15.00 VESTING Prvt	0.00%	2,830
271	n/a	OMNIAB INC $12.50 VESTING Prvt	0.00%	2,830
272	n/a	Cash Offset	-0.33%	1,500,880

As of Jun 12, 2025

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