iShares NASDAQ US Biotechnology UCITS ETF (LON:BTEC)

LON:BTEC Holdings List

As of May 16, 2025

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No.	Symbol	Name	% Weight	Shares
1	VRTX	Vertex Pharmaceuticals Incorporated	8.22%	79,546
2	GILD	Gilead Sciences, Inc.	8.07%	333,870
3	AMGN	Amgen Inc.	7.95%	123,885
4	REGN	Regeneron Pharmaceuticals, Inc.	7.17%	51,171
5	AZN	AstraZeneca PLC	4.49%	277,146
6	ALNY	Alnylam Pharmaceuticals, Inc.	4.14%	61,610
7	BIIB	Biogen Inc.	2.06%	69,667
8	ARGX	argenx SE	2.03%	15,235
9	SMMT	Summit Therapeutics Inc.	1.98%	351,143
10	SNY	Sanofi	1.67%	136,780
11	RPRX	Royalty Pharma plc	1.65%	206,269
12	UTHR	United Therapeutics Corporation	1.54%	21,369
13	ILMN	Illumina, Inc.	1.49%	75,399
14	EXEL	Exelixis, Inc.	1.43%	133,230
15	INSM	Insmed Incorporated	1.38%	86,162
16	INCY	Incyte Corporation	1.37%	92,126
17	NBIX	Neurocrine Biosciences, Inc.	1.35%	47,469
18	BMRN	BioMarin Pharmaceutical Inc.	1.27%	90,804
19	TEM	Tempus AI, Inc.	1.23%	79,587
20	VTRS	Viatris Inc.	1.18%	568,226
21	MRNA	Moderna, Inc.	1.08%	183,654
22	ONC	BeiGene, Ltd.	1.07%	19,924
23	ASND	Ascendis Pharma A/S	1.07%	28,753
24	MEDP	Medpace Holdings, Inc.	1.04%	14,494
25	BNTX	BioNTech SE	1.04%	47,360
26	ROIV	Roivant Sciences Ltd.	0.86%	339,700
27	RVMD	Revolution Medicines, Inc.	0.82%	88,512
28	JAZZ	Jazz Pharmaceuticals plc	0.74%	28,911
29	BPMC	Blueprint Medicines Corporation	0.73%	30,429
30	BBIO	BridgeBio Pharma, Inc.	0.72%	90,548
31	MDGL	Madrigal Pharmaceuticals, Inc.	0.72%	10,507
32	HALO	Halozyme Therapeutics, Inc.	0.72%	58,634
33	VRNA	Verona Pharma plc	0.63%	37,520
34	IONS	Ionis Pharmaceuticals, Inc.	0.60%	75,699
35	AXSM	Axsome Therapeutics, Inc.	0.59%	23,216
36	ALKS	Alkermes plc	0.57%	77,429
37	GH	Guardant Health, Inc.	0.56%	58,768
38	NUVL	Nuvalent, Inc.	0.54%	31,504
39	ADMA	ADMA Biologics, Inc.	0.52%	112,562
40	PCVX	Vaxcyte, Inc.	0.46%	61,313
41	RYTM	Rhythm Pharmaceuticals, Inc.	0.43%	30,106
42	KRYS	Krystal Biotech, Inc.	0.42%	13,714
43	ACAD	ACADIA Pharmaceuticals Inc.	0.42%	79,495
44	CYTK	Cytokinetics, Incorporated	0.41%	56,380
45	RNA	Avidity Biosciences, Inc.	0.41%	57,237
46	PTCT	PTC Therapeutics, Inc.	0.41%	37,558
47	SRPT	Sarepta Therapeutics, Inc.	0.40%	46,201
48	SWTX	SpringWorks Therapeutics, Inc.	0.39%	35,686
49	CRSP	CRISPR Therapeutics AG	0.37%	40,847
50	RARE	Ultragenyx Pharmaceutical Inc.	0.37%	44,043
51	ACLX	Arcellx, Inc.	0.36%	26,168
52	ALVO	Alvotech	0.35%	141,311
53	AKRO	Akero Therapeutics, Inc.	0.35%	37,917
54	CRNX	Crinetics Pharmaceuticals, Inc.	0.33%	44,302
55	SRRK	Scholar Rock Holding Corporation	0.32%	45,083
56	MRUS	Merus N.V.	0.32%	32,906
57	PTGX	Protagonist Therapeutics, Inc.	0.31%	29,231
58	IMVT	Immunovant, Inc.	0.28%	80,895
59	AMRX	Amneal Pharmaceuticals, Inc.	0.26%	147,886
60	VCYT	Veracyte, Inc.	0.26%	37,276
61	XENE	Xenon Pharmaceuticals Inc.	0.26%	35,881
62	LEGN	Legend Biotech Corporation	0.25%	38,933
63	MIRM	Mirum Pharmaceuticals, Inc.	0.25%	23,463
64	APLS	Apellis Pharmaceuticals, Inc.	0.25%	59,839
65	BCRX	BioCryst Pharmaceuticals, Inc.	0.24%	100,830
66	VCEL	Vericel Corporation	0.24%	23,919
67	IBRX	ImmunityBio, Inc.	0.23%	349,455
68	NAMS	NewAmsterdam Pharma Company N.V.	0.23%	51,469
69	LGND	Ligand Pharmaceuticals Incorporated	0.23%	9,236
70	DNLI	Denali Therapeutics Inc.	0.23%	69,661
71	ARWR	Arrowhead Pharmaceuticals, Inc.	0.23%	60,809
72	KYMR	Kymera Therapeutics, Inc.	0.22%	31,236
73	FOLD	Amicus Therapeutics, Inc.	0.22%	146,675
74	HRMY	Harmony Biosciences Holdings, Inc.	0.22%	26,882
75	n/a	E-MINI HEALTH CARE SECTOR JUN 25	0.22%	7
76	CGON	CG Oncology, Inc.	0.22%	36,574
77	NVCR	NovoCure Limited	0.22%	51,525
78	ZLAB	Zai Lab Limited	0.21%	29,309
79	TWST	Twist Bioscience Corporation	0.21%	28,518
80	APGE	Apogee Therapeutics, Inc.	0.21%	21,688
81	SUPN	Supernus Pharmaceuticals, Inc.	0.21%	26,164
82	RXRX	Recursion Pharmaceuticals, Inc.	0.20%	189,276
83	AGIO	Agios Pharmaceuticals, Inc.	0.19%	27,596
84	TARS	Tarsus Pharmaceuticals, Inc.	0.19%	18,421
85	ARQT	Arcutis Biotherapeutics, Inc.	0.19%	56,994
86	IRON	Disc Medicine, Inc.	0.19%	16,642
87	n/a	USD - OTHER PAYABLES/RECEIVABLES	0.19%	796,104
88	IDYA	IDEAYA Biosciences, Inc.	0.18%	42,350
89	BEAM	Beam Therapeutics Inc.	0.17%	40,329
90	TVTX	Travere Therapeutics, Inc.	0.17%	42,810
91	GPCR	Structure Therapeutics Inc.	0.17%	27,914
92	JANX	Janux Therapeutics, Inc.	0.16%	28,510
93	EWTX	Edgewise Therapeutics, Inc.	0.16%	45,366
94	LON: INDV	Indivior PLC	0.16%	58,166
95	VERA	Vera Therapeutics, Inc.	0.15%	30,785
96	n/a	USD - Spendable Cash	0.15%	643,822
97	SPRY	ARS Pharmaceuticals, Inc.	0.15%	47,269
98	MNKD	MannKind Corporation	0.15%	146,592
99	GRAL	GRAIL, Inc.	0.15%	16,024
100	ANIP	ANI Pharmaceuticals, Inc.	0.15%	10,523
101	DYN	Dyne Therapeutics, Inc.	0.15%	53,004
102	ADPT	Adaptive Biotechnologies Corporation	0.15%	69,222
103	AMPH	Amphastar Pharmaceuticals, Inc.	0.14%	23,282
104	DVAX	Dynavax Technologies Corporation	0.13%	58,890
105	IMCR	Immunocore Holdings plc	0.13%	18,574
106	PCRX	Pacira BioSciences, Inc.	0.13%	21,687
107	CNTA	Centessa Pharmaceuticals plc	0.13%	44,289
108	AUPH	Aurinia Pharmaceuticals Inc.	0.13%	66,817
109	INVA	Innoviva, Inc.	0.13%	29,367
110	OCUL	Ocular Therapeutix, Inc.	0.13%	73,658
111	ETNB	89bio, Inc.	0.13%	68,385
112	n/a	RUSSELL 2000 EMINI CME JUN 25	0.12%	5
113	KNSA	Kiniksa Pharmaceuticals International, plc	0.12%	19,683
114	NVAX	Novavax, Inc.	0.12%	75,355
115	HROW	Harrow, Inc.	0.11%	16,946
116	TXG	10x Genomics, Inc.	0.11%	50,708
117	WVE	Wave Life Sciences Ltd.	0.11%	74,149
118	COLL	Collegium Pharmaceutical, Inc.	0.11%	15,182
119	GRFS	Grifols, S.A.	0.11%	58,673
120	ARDX	Ardelyx, Inc.	0.10%	111,669
121	SYRE	Spyre Therapeutics, Inc.	0.10%	28,222
122	AVDL	Avadel Pharmaceuticals plc	0.10%	45,870
123	NTLA	Intellia Therapeutics, Inc.	0.10%	48,479
124	CVAC	CureVac N.V.	0.09%	107,953
125	GMAB	Genmab A/S	0.09%	19,900
126	ELVN	Enliven Therapeutics, Inc.	0.09%	22,989
127	ZYME	Zymeworks Inc.	0.09%	32,694
128	GERN	Geron Corporation	0.09%	298,341
129	MLYS	Mineralys Therapeutics, Inc.	0.09%	23,875
130	SNDX	Syndax Pharmaceuticals, Inc.	0.09%	40,000
131	CRMD	CorMedix Inc.	0.08%	29,300
132	LENZ	LENZ Therapeutics, Inc.	0.08%	13,216
133	PRAX	Praxis Precision Medicines, Inc.	0.08%	9,451
134	QURE	uniQure N.V.	0.08%	25,317
135	XERS	Xeris Biopharma Holdings, Inc.	0.08%	69,817
136	NRIX	Nurix Therapeutics, Inc.	0.08%	35,547
137	AVXL	Anavex Life Sciences Corp.	0.08%	40,384
138	RCKT	Rocket Pharmaceuticals, Inc.	0.08%	49,928
139	AVBP	ArriVent BioPharma, Inc.	0.07%	16,169
140	DAWN	Day One Biopharmaceuticals, Inc.	0.07%	47,962
141	VIR	Vir Biotechnology, Inc.	0.07%	64,848
142	ANAB	AnaptysBio, Inc.	0.07%	14,728
143	REPL	Replimune Group, Inc.	0.07%	37,532
144	EOLS	Evolus, Inc.	0.07%	30,082
145	ABCL	AbCellera Biologics Inc.	0.07%	141,198
146	ABUS	Arbutus Biopharma Corporation	0.07%	91,695
147	KALV	KalVista Pharmaceuticals, Inc.	0.07%	23,396
148	TRVI	Trevi Therapeutics, Inc.	0.06%	41,832
149	XNCR	Xencor, Inc.	0.06%	33,285
150	COGT	Cogent Biosciences, Inc.	0.06%	53,298
151	KROS	Keros Therapeutics, Inc.	0.06%	18,406
152	STOK	Stoke Therapeutics, Inc.	0.06%	26,327
153	IOVA	Iovance Biotherapeutics, Inc.	0.06%	153,605
154	SVRA	Savara Inc.	0.06%	80,557
155	TSHA	Taysha Gene Therapies, Inc.	0.06%	91,515
156	TYRA	Tyra Biosciences, Inc.	0.06%	24,621
157	PAHC	Phibro Animal Health Corporation	0.06%	10,109
158	MNMD	Mind Medicine (MindMed) Inc.	0.06%	36,405
159	ZVRA	Zevra Therapeutics, Inc.	0.05%	26,764
160	CSTL	Castle Biosciences, Inc.	0.05%	13,716
161	KURA	Kura Oncology, Inc.	0.05%	37,983
162	RLAY	Relay Therapeutics, Inc.	0.05%	81,044
163	RGNX	REGENXBIO Inc.	0.05%	24,669
164	ARVN	Arvinas, Inc.	0.05%	33,439
165	CGEM	Cullinan Therapeutics, Inc.	0.05%	28,658
166	SIGA	SIGA Technologies, Inc.	0.05%	35,878
167	TBPH	Theravance Biopharma, Inc.	0.05%	23,115
168	EYPT	EyePoint Pharmaceuticals, Inc.	0.05%	34,494
169	TRML	Tourmaline Bio, Inc.	0.05%	12,682
170	PGEN	Precigen, Inc.	0.05%	142,927
171	PSNL	Personalis, Inc.	0.05%	41,277
172	ALT	Altimmune, Inc.	0.05%	36,015
173	VERV	Verve Therapeutics, Inc.	0.05%	43,359
174	HCM	HUTCHMED (China) Limited	0.05%	14,976
175	SAGE	Sage Therapeutics, Inc.	0.05%	28,973
176	GLPG	Galapagos NV	0.05%	7,139
177	AMLX	Amylyx Pharmaceuticals, Inc.	0.05%	40,068
178	MESO	Mesoblast Limited	0.04%	15,982
179	FTRE	Fortrea Holdings Inc.	0.04%	41,801
180	PRTA	Prothena Corporation plc	0.04%	25,748
181	MGTX	MeiraGTx Holdings plc	0.04%	37,034
182	RAPP	Rapport Therapeutics, Inc.	0.04%	18,524
183	ERAS	Erasca, Inc.	0.04%	142,158
184	SANA	Sana Biotechnology, Inc.	0.04%	104,416
185	RIGL	Rigel Pharmaceuticals, Inc.	0.04%	9,076
186	BCYC	Bicycle Therapeutics plc	0.04%	22,215
187	ORKA	Oruka Therapeutics, Inc.	0.04%	17,713
188	OLMA	Olema Pharmaceuticals, Inc.	0.04%	34,712
189	ORIC	ORIC Pharmaceuticals, Inc.	0.04%	33,897
190	TKNO	Alpha Teknova, Inc.	0.04%	23,812
191	ARCT	Arcturus Therapeutics Holdings Inc.	0.04%	13,375
192	TRDA	Entrada Therapeutics, Inc.	0.04%	19,126
193	MRVI	Maravai LifeSciences Holdings, Inc.	0.04%	73,150
194	URGN	UroGen Pharma Ltd.	0.04%	20,517
195	ABSI	Absci Corporation	0.03%	51,269
196	PACB	Pacific Biosciences of California, Inc.	0.03%	138,088
197	PHAT	Phathom Pharmaceuticals, Inc.	0.03%	34,018
198	TECX	Tectonic Therapeutic, Inc.	0.03%	6,582
199	AUTL	Autolus Therapeutics plc	0.03%	101,823
200	RNAC	Cartesian Therapeutics, Inc.	0.03%	12,998
201	AURA	Aura Biosciences, Inc.	0.03%	22,323
202	HUMA	Humacyte, Inc.	0.03%	58,215
203	ITOS	iTeos Therapeutics, Inc.	0.03%	15,980
204	VNDA	Vanda Pharmaceuticals Inc.	0.03%	29,911
205	NGNE	Neurogene Inc.	0.03%	6,640
206	ALMS	Alumis Inc.	0.03%	21,111
207	SLRN	Acelyrin, Inc.	0.03%	52,613
208	CMPS	COMPASS Pathways plc	0.03%	29,339
209	n/a	GBP - Spendable Cash	0.03%	87,198
210	MXCT	MaxCyte, Inc.	0.03%	49,975
211	ALLO	Allogene Therapeutics, Inc.	0.03%	102,270
212	INZY	Inozyme Pharma, Inc.	0.03%	28,690
213	n/a	CASH COLLATERAL USD HSBFT	0.03%	112,000
214	TERN	Terns Pharmaceuticals, Inc.	0.03%	38,591
215	FHTX	Foghorn Therapeutics Inc.	0.03%	24,826
216	CDXS	Codexis, Inc.	0.03%	44,432
217	GLUE	Monte Rosa Therapeutics, Inc.	0.03%	27,448
218	AMRN	Amarin Corporation plc	0.03%	10,213
219	AVIR	Atea Pharmaceuticals, Inc.	0.03%	39,167
220	THRD	Third Harmonic Bio, Inc.	0.03%	20,651
221	CRVS	Corvus Pharmaceuticals, Inc.	0.02%	28,697
222	ATXS	Astria Therapeutics, Inc.	0.02%	25,212
223	SLDB	Solid Biosciences Inc.	0.02%	35,677
224	AQST	Aquestive Therapeutics, Inc.	0.02%	40,709
225	ANNX	Annexon, Inc.	0.02%	47,606
226	LXRX	Lexicon Pharmaceuticals, Inc.	0.02%	176,648
227	PRME	Prime Medicine, Inc.	0.02%	58,689
228	OMER	Omeros Corporation	0.02%	28,636
229	SLN	Silence Therapeutics plc	0.02%	21,003
230	OABI	OmniAb, Inc.	0.02%	57,536
231	DSGN	Design Therapeutics, Inc.	0.02%	25,286
232	TVGN	Tevogen Bio Holdings Inc.	0.02%	78,173
233	CRGX	CARGO Therapeutics, Inc.	0.02%	20,562
234	YMAB	Y-mAbs Therapeutics, Inc.	0.02%	19,643
235	ACIU	AC Immune SA	0.02%	46,649
236	INBX	Inhibrx Biosciences, Inc.	0.02%	6,458
237	VYGR	Voyager Therapeutics, Inc.	0.02%	23,997
238	TNGX	Tango Therapeutics, Inc.	0.02%	52,230
239	SCPH	scPharmaceuticals Inc.	0.02%	22,366
240	FDMT	4D Molecular Therapeutics, Inc.	0.02%	20,658
241	ESPR	Esperion Therapeutics, Inc.	0.02%	87,981
242	ALEC	Alector, Inc.	0.01%	49,667
243	EDIT	Editas Medicine, Inc.	0.01%	38,328
244	LRMR	Larimar Therapeutics, Inc.	0.01%	28,493
245	NKTX	Nkarta, Inc.	0.01%	31,525
246	ENTA	Enanta Pharmaceuticals, Inc.	0.01%	9,479
247	FATE	Fate Therapeutics, Inc.	0.01%	50,870
248	LYEL	Lyell Immunopharma, Inc.	0.01%	127,776
249	NMRA	Neumora Therapeutics, Inc.	0.01%	72,143
250	LXEO	Lexeo Therapeutics, Inc.	0.01%	14,768
251	MGNX	MacroGenics, Inc.	0.01%	28,773
252	KYTX	Kyverna Therapeutics, Inc.	0.01%	19,291
253	CCCC	C4 Therapeutics, Inc.	0.01%	31,535
254	IRWD	Ironwood Pharmaceuticals, Inc.	0.01%	71,294
255	CLYM	Climb Bio, Inc.	0.01%	30,021
256	PLRX	Pliant Therapeutics, Inc.	0.01%	27,184
257	STRO	Sutro Biopharma, Inc.	0.01%	36,822
258	PYXS	Pyxis Oncology, Inc.	0.01%	26,563
259	APLT	Applied Therapeutics, Inc.	0.01%	51,955
260	TCRX	TScan Therapeutics, Inc.	0.01%	21,931
261	BMEA	Biomea Fusion, Inc.	0.01%	17,604
262	PEPG	PepGen Inc.	0.01%	14,564
263	ARTV	Artiva Biotherapeutics, Inc.	0.01%	10,863
264	MRSN	Mersana Therapeutics, Inc.	0.00%	55,170
265	IGMS	IGM Biosciences, Inc.	0.00%	15,234
266	ACRV	Acrivon Therapeutics, Inc.	0.00%	13,903
267	QTTB	Q32 Bio Inc.	0.00%	7,145
268	OKUR	OnKure Therapeutics, Inc.	0.00%	5,644
269	n/a	EUR - Spendable Cash	0.00%	4,119
270	n/a	OMNIAB INC $15.00 VESTING Prvt	0.00%	2,830
271	n/a	OMNIAB INC $12.50 VESTING Prvt	0.00%	2,830
272	n/a	Cash Offset	-0.35%	1,472,260

As of May 16, 2025

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