Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · IEX Real-Time Price · USD
49.47
-0.47 (-0.94%)
Dec 7, 2023, 4:00 PM EST - Market closed
-0.94%
Market Cap 7.16B
Revenue (ttm) 615.03M
Net Income (ttm) -409.45M
Shares Out 143.47M
EPS (ttm) -2.87
PE Ratio n/a
Forward PE 90.91
Dividend n/a
Ex-Dividend Date n/a
Volume 715,887
Open 50.12
Previous Close 49.94
Day's Range 49.33 - 50.12
52-Week Range 32.69 - 51.89
Beta 0.49
Analysts Hold
Price Target 50.38 (+1.84%)
Earnings Date Nov 2, 2023

About IONS

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 17, 1991
Employees 796
Stock Exchange NASDAQ
Ticker Symbol IONS
Full Company Profile

Financial Performance

In 2022, IONS's revenue was $587.37 million, a decrease of -27.53% compared to the previous year's $810.46 million. Losses were -$269.72 million, 843.2% more than in 2021.

Financial Statements

Analyst Forecast

According to 13 analysts, the average rating for IONS stock is "Hold." The 12-month stock price forecast is $50.38, which is an increase of 1.84% from the latest price.

Price Target
$50.38
(1.84% upside)
Analyst Consensus: Hold
Stock Forecasts

News

Ionis shares positive clinical update from ongoing trial of ION582 for Angelman syndrome

Part 1 of HALOS trial evaluating ION582 has completed enrollment with results expected in mid-2024 ION582 has been generally well tolerated at all dose levels, and participants are continuing to Part ...

26 days ago - PRNewsWire

Ionis presents positive two-year results from the Phase 2 open label extension study of donidalorsen in patients with hereditary angioedema

Continued treatment over two years with donidalorsen demonstrated sustained reduction in hereditary angioedema attacks and improved quality of life Donidalorsen recently received orphan drug designati...

4 weeks ago - PRNewsWire

Ionis to present at upcoming investor conferences

CARLSBAD, Calif. , Nov. 3, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Gug...

4 weeks ago - PRNewsWire

Ionis reports third quarter 2023 financial results

Olezarsen Phase 3 data showed significant triglyceride lowering, substantial reductions in acute pancreatitis attacks and favorable safety and tolerability in patients with FCS; on track for regulator...

5 weeks ago - PRNewsWire

Ionis to hold third quarter 2023 financial results webcast

Webcast scheduled for Thursday, November 2 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

7 weeks ago - PRNewsWire

Ionis shares significant business and pipeline progress at Innovation Day, highlighting strength of capabilities from research and technology through commercialization

With experienced commercial team in place, Ionis poised to independently bring steady cadence of potentially transformational RNA-targeted medicines to patients beginning in 2024 Plan to add four new ...

2 months ago - PRNewsWire

Eplontersen Phase 3 results published in JAMA show consistent and sustained benefit

Publication of NEURO-TTRansform study in patients with hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN) showed eplontersen halted disease progression and continuously improved quali...

2 months ago - PRNewsWire

Ionis enters agreement with Roche for two novel RNA-targeted programs for Alzheimer's disease and Huntington's disease

Roche gains exclusive worldwide rights to develop, manufacture and commercialize the investigational medicines discovered by Ionis Ionis to receive a $60 million upfront payment CARLSBAD, Calif. , Sep...

2 months ago - PRNewsWire

Ionis Pharma's genetic disorder drug meets main goal in late-stage study

Ionis Pharmaceuticals said on Tuesday its experimental drug met main goal in a late-stage trial testing it as a treatment for a rare genetic disorder known as familial chylomicronemia syndrome.

2 months ago - Reuters

Ionis announces positive olezarsen topline results from Phase 3 study in people with familial chylomicronemia syndrome

Olezarsen met the primary endpoint with a statistically significant reduction in triglyceride levels versus placebo First study to show an absolute reduction in acute pancreatitis in FCS patients, wit...

2 months ago - PRNewsWire

Ionis to host investor and analyst day event

Ionis Innovation Day: Discovering, Developing and Delivering Transformational Medicines Presentations by key members of Ionis leadership and notable KOLs CARLSBAD, Calif. , Sept. 12, 2023 /PRNewswire/...

3 months ago - PRNewsWire

Ionis reports second quarter 2023 financial results

Reported Phase 3 data showing eplontersen continued to show improvement in ATTRv-PN through 85 weeks; December 22, 2023 PDUFA date Completed enrollment in donidalorsen OASIS-HAE study and eplontersen ...

4 months ago - PRNewsWire

Ionis enters collaboration to advance next generation program targeting Lp(a) for cardiovascular disease

Builds on existing collaboration with Novartis for pelacarsen, which is currently being evaluated in a Phase 3 cardiovascular outcome study with data expected in 2025 Ionis' new and advanced technolog...

4 months ago - PRNewsWire

Ionis completes enrollment in landmark Phase 3 CARDIO-TTRansform study in patients with TTR-mediated amyloid cardiomyopathy

CARDIO-TTRansform is the largest, most comprehensive ATTR-CM study with more than 1,400 patients enrolled Eplontersen is currently under U.S. FDA review for ATTRv-polyneuropathy, with ATTR-CM represen...

4 months ago - PRNewsWire

Ionis expands eplontersen agreement with AstraZeneca to include exclusive rights in Latin America

Companies jointly developing and commercializing eplontersen in the U.S.  AstraZeneca adds Latin America as part of its exclusive rights for rest of world CARLSBAD, Calif. , July 28, 2023 /PRNewswire/...

4 months ago - PRNewsWire

Ionis to hold second quarter 2023 financial results webcast

Webcast scheduled for Wednesday, August 9 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

4 months ago - PRNewsWire

Scipher Medicine Signs Multi-Target Partnership with Ionis

WALTHAM, Mass.--(BUSINESS WIRE)--Scipher Medicine Signs Multi-Target Partnership with Ionis Pharmaceuticals.

5 months ago - Business Wire

Eplontersen continued to show improvement in ATTRv-PN through 85 weeks

Topline Phase 3 NEURO-TTRansform results show eplontersen continued to halt neuropathy disease progression and improve quality of life through 85 weeks Data further strengthen eplontersen's differenti...

5 months ago - PRNewsWire

Ionis to present at upcoming investor conference

CARLSBAD, Calif. , July 5, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in a fireside chat at TD Cowen's 2nd Annual RNA Therapeutics...

5 months ago - PRNewsWire

New data highlight potential benefit of SPINRAZA® (nusinersen) in infants and toddlers with unmet medical needs after gene therapy

Interim results from RESPOND study show improved motor function in most participants treated with SPINRAZA after Zolgensma® (onasemnogene abeparvovec)  CARLSBAD, Calif. , June 30, 2023 /PRNewswire/ --...

5 months ago - PRNewsWire

Ionis prices private placement of convertible senior notes

CARLSBAD, Calif. , June 7, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today the pricing of $500.0 million aggregate principal amount of 1.75% Convertible Senior Notes du...

6 months ago - PRNewsWire

Ionis announces proposed private placement of convertible notes

CARLSBAD, Calif. , June 6, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today that it intends to offer, subject to market conditions and other factors, $500.0 million aggr...

6 months ago - PRNewsWire

Ionis announces positive donidalorsen late-stage clinical progress in HAE

Two-year treatment with donidalorsen in the Phase 2 open label study resulted in consistent, sustained protection from HAE attacks Completed enrollment in the Phase 3 OASIS-HAE study Topline Phase 3 r...

6 months ago - PRNewsWire

Ionis to host 2023 virtual Annual Meeting of Stockholders

CARLSBAD, Calif. , May 10, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will conduct its 2023 virtual Annual Meeting of Stockholders followed by a ge...

7 months ago - PRNewsWire

Ionis reports first quarter 2023 financial results

QALSODY approved for SOD1-ALS; MAA under review in EU Reported positive Phase 3 eplontersen ATTRv-PN data; December 22, 2023 PDUFA date On track to achieve 2023 financial guidance CARLSBAD, Calif. , M...

7 months ago - PRNewsWire