Ionis Pharmaceuticals, Inc. (IONS)
Market Cap | 7.16B |
Revenue (ttm) | 615.03M |
Net Income (ttm) | -409.45M |
Shares Out | 143.47M |
EPS (ttm) | -2.87 |
PE Ratio | n/a |
Forward PE | 90.91 |
Dividend | n/a |
Ex-Dividend Date | n/a |
Volume | 715,887 |
Open | 50.12 |
Previous Close | 49.94 |
Day's Range | 49.33 - 50.12 |
52-Week Range | 32.69 - 51.89 |
Beta | 0.49 |
Analysts | Hold |
Price Target | 50.38 (+1.84%) |
Earnings Date | Nov 2, 2023 |
About IONS
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen ... [Read more]
Financial Performance
In 2022, IONS's revenue was $587.37 million, a decrease of -27.53% compared to the previous year's $810.46 million. Losses were -$269.72 million, 843.2% more than in 2021.
Financial StatementsAnalyst Forecast
According to 13 analysts, the average rating for IONS stock is "Hold." The 12-month stock price forecast is $50.38, which is an increase of 1.84% from the latest price.
News

Ionis shares positive clinical update from ongoing trial of ION582 for Angelman syndrome
Part 1 of HALOS trial evaluating ION582 has completed enrollment with results expected in mid-2024 ION582 has been generally well tolerated at all dose levels, and participants are continuing to Part ...

Ionis presents positive two-year results from the Phase 2 open label extension study of donidalorsen in patients with hereditary angioedema
Continued treatment over two years with donidalorsen demonstrated sustained reduction in hereditary angioedema attacks and improved quality of life Donidalorsen recently received orphan drug designati...

Ionis to present at upcoming investor conferences
CARLSBAD, Calif. , Nov. 3, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Gug...

Ionis reports third quarter 2023 financial results
Olezarsen Phase 3 data showed significant triglyceride lowering, substantial reductions in acute pancreatitis attacks and favorable safety and tolerability in patients with FCS; on track for regulator...

Ionis to hold third quarter 2023 financial results webcast
Webcast scheduled for Thursday, November 2 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

Ionis shares significant business and pipeline progress at Innovation Day, highlighting strength of capabilities from research and technology through commercialization
With experienced commercial team in place, Ionis poised to independently bring steady cadence of potentially transformational RNA-targeted medicines to patients beginning in 2024 Plan to add four new ...

Eplontersen Phase 3 results published in JAMA show consistent and sustained benefit
Publication of NEURO-TTRansform study in patients with hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN) showed eplontersen halted disease progression and continuously improved quali...

Ionis enters agreement with Roche for two novel RNA-targeted programs for Alzheimer's disease and Huntington's disease
Roche gains exclusive worldwide rights to develop, manufacture and commercialize the investigational medicines discovered by Ionis Ionis to receive a $60 million upfront payment CARLSBAD, Calif. , Sep...

Ionis Pharma's genetic disorder drug meets main goal in late-stage study
Ionis Pharmaceuticals said on Tuesday its experimental drug met main goal in a late-stage trial testing it as a treatment for a rare genetic disorder known as familial chylomicronemia syndrome.

Ionis announces positive olezarsen topline results from Phase 3 study in people with familial chylomicronemia syndrome
Olezarsen met the primary endpoint with a statistically significant reduction in triglyceride levels versus placebo First study to show an absolute reduction in acute pancreatitis in FCS patients, wit...

Ionis to host investor and analyst day event
Ionis Innovation Day: Discovering, Developing and Delivering Transformational Medicines Presentations by key members of Ionis leadership and notable KOLs CARLSBAD, Calif. , Sept. 12, 2023 /PRNewswire/...

Ionis reports second quarter 2023 financial results
Reported Phase 3 data showing eplontersen continued to show improvement in ATTRv-PN through 85 weeks; December 22, 2023 PDUFA date Completed enrollment in donidalorsen OASIS-HAE study and eplontersen ...

Ionis enters collaboration to advance next generation program targeting Lp(a) for cardiovascular disease
Builds on existing collaboration with Novartis for pelacarsen, which is currently being evaluated in a Phase 3 cardiovascular outcome study with data expected in 2025 Ionis' new and advanced technolog...

Ionis completes enrollment in landmark Phase 3 CARDIO-TTRansform study in patients with TTR-mediated amyloid cardiomyopathy
CARDIO-TTRansform is the largest, most comprehensive ATTR-CM study with more than 1,400 patients enrolled Eplontersen is currently under U.S. FDA review for ATTRv-polyneuropathy, with ATTR-CM represen...

Ionis expands eplontersen agreement with AstraZeneca to include exclusive rights in Latin America
Companies jointly developing and commercializing eplontersen in the U.S. AstraZeneca adds Latin America as part of its exclusive rights for rest of world CARLSBAD, Calif. , July 28, 2023 /PRNewswire/...

Ionis to hold second quarter 2023 financial results webcast
Webcast scheduled for Wednesday, August 9 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

Scipher Medicine Signs Multi-Target Partnership with Ionis
WALTHAM, Mass.--(BUSINESS WIRE)--Scipher Medicine Signs Multi-Target Partnership with Ionis Pharmaceuticals.

Eplontersen continued to show improvement in ATTRv-PN through 85 weeks
Topline Phase 3 NEURO-TTRansform results show eplontersen continued to halt neuropathy disease progression and improve quality of life through 85 weeks Data further strengthen eplontersen's differenti...

Ionis to present at upcoming investor conference
CARLSBAD, Calif. , July 5, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in a fireside chat at TD Cowen's 2nd Annual RNA Therapeutics...

New data highlight potential benefit of SPINRAZA® (nusinersen) in infants and toddlers with unmet medical needs after gene therapy
Interim results from RESPOND study show improved motor function in most participants treated with SPINRAZA after Zolgensma® (onasemnogene abeparvovec) CARLSBAD, Calif. , June 30, 2023 /PRNewswire/ --...

Ionis prices private placement of convertible senior notes
CARLSBAD, Calif. , June 7, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today the pricing of $500.0 million aggregate principal amount of 1.75% Convertible Senior Notes du...

Ionis announces proposed private placement of convertible notes
CARLSBAD, Calif. , June 6, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today that it intends to offer, subject to market conditions and other factors, $500.0 million aggr...

Ionis announces positive donidalorsen late-stage clinical progress in HAE
Two-year treatment with donidalorsen in the Phase 2 open label study resulted in consistent, sustained protection from HAE attacks Completed enrollment in the Phase 3 OASIS-HAE study Topline Phase 3 r...

Ionis to host 2023 virtual Annual Meeting of Stockholders
CARLSBAD, Calif. , May 10, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will conduct its 2023 virtual Annual Meeting of Stockholders followed by a ge...

Ionis reports first quarter 2023 financial results
QALSODY approved for SOD1-ALS; MAA under review in EU Reported positive Phase 3 eplontersen ATTRv-PN data; December 22, 2023 PDUFA date On track to achieve 2023 financial guidance CARLSBAD, Calif. , M...