Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · IEX Real-Time Price · USD
40.68
-0.13 (-0.32%)
At close: Apr 19, 2024, 4:00 PM
40.69
+0.01 (0.02%)
After-hours: Apr 19, 2024, 4:29 PM EDT
-0.32%
Market Cap 5.93B
Revenue (ttm) 787.65M
Net Income (ttm) -366.29M
Shares Out 145.75M
EPS (ttm) -2.56
PE Ratio n/a
Forward PE 90.91
Dividend n/a
Ex-Dividend Date n/a
Volume 846,040
Open 40.88
Previous Close 40.81
Day's Range 40.39 - 41.23
52-Week Range 34.32 - 54.44
Beta 0.40
Analysts Buy
Price Target 58.00 (+42.58%)
Earnings Date May 1, 2024

About IONS

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 17, 1991
Employees 927
Stock Exchange NASDAQ
Ticker Symbol IONS
Full Company Profile

Financial Performance

In 2023, IONS's revenue was $787.65 million, an increase of 34.10% compared to the previous year's $587.37 million. Losses were -$366.29 million, 35.8% more than in 2022.

Financial Statements

Analyst Forecast

According to 13 analysts, the average rating for IONS stock is "Buy." The 12-month stock price forecast is $58.0, which is an increase of 42.58% from the latest price.

Price Target
$58.0
(42.58% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Ionis presents positive results from Phase 3 Balance study of olezarsen for familial chylomicronemia syndrome

–         Olezarsen met the primary endpoint with statistically significant reduction of fasting triglycerides and showed substantial, clinically meaningful reduction in acute pancreatitis events – – ...

12 days ago - PRNewsWire

Ionis to present at upcoming investor conferences

CARLSBAD, Calif. , April 1, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: 23...

18 days ago - PRNewsWire

Ionis to hold olezarsen Phase 3 data webcast

Webcast scheduled for Monday, April 8 at 10:00 a.m. Eastern Time CARLSBAD, Calif.

22 days ago - PRNewsWire

Positive olezarsen Phase 3 data in familial chylomicronemia syndrome to be presented at 2024 American College of Cardiology (ACC) annual meeting

–  First presentation of pivotal results showing significant reduction in triglycerides and substantial reduction in acute pancreatitis events in patients with rare, life-threatening disease, for whic...

25 days ago - PRNewsWire

Ionis Pharma's fatty liver disease drug succeeds in mid-stage trial

Ionis Pharmaceuticals said on Wednesday its experimental drug to treat a type of fatty liver disease met the main goal of a mid-stage trial.

5 weeks ago - Reuters

Ionis announces positive results from Phase 2 study of ION224, an investigational medicine demonstrating clinical efficacy in the treatment of NASH/MASH

Significant improvement in steatohepatitis with > 2 point improvement in NAS score without worsening fibrosis, the primary endpoint of the study Achieved key secondary endpoint of MASH resolution with...

5 weeks ago - PRNewsWire

Ionis announces new chief global product strategy officer to lead next phase of commercial growth

Kyle Jenne  rejoins company to lead commercial strategy Onaiza Cadoret-Manier departing for new career opportunity With broad commercial capabilities in place, Ionis ready to execute on its first inde...

7 weeks ago - PRNewsWire

Ionis reports fourth quarter and full year 2023 financial results

WAINUA™  approved with launch underway; on track for EU and Canada approval decisions this year Positive Phase 3 olezarsen and donidalorsen data, preparing regulatory submissions for FCS and HAE, resp...

2 months ago - PRNewsWire

Olezarsen receives Orphan Drug designation from U.S. FDA for familial chylomicronemia syndrome

CARLSBAD, Calif. , Feb. 15, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug designation to the ...

2 months ago - PRNewsWire

Eplontersen granted U.S. FDA Fast Track designation for patients with transthyretin-mediated amyloid cardiomyopathy

CARLSBAD, Calif. , Feb. 8, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to Ionis ...

2 months ago - PRNewsWire

Ionis to hold fourth quarter and full year 2023 financial results webcast

Webcast scheduled for Wednesday, February 21 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

2 months ago - PRNewsWire

Vect-Horus Enters Exclusive License Agreement with Ionis Pharmaceuticals to Advance Systemic Delivery of RNA-Targeted Medicines for Neurological Diseases

MARSEILLE, France--(BUSINESS WIRE)--Vect-Horus announced it has entered into a global license agreement with Ionis Pharmaceuticals, Inc. (Nasdaq: IONS).

2 months ago - Business Wire

Ionis Pharma's genetic disease drug succeeds in late-stage study

Ionis Pharmaceuticals said on Monday its therapy for the treatment of a rare genetic disease met the main goal in a late-stage trial.

3 months ago - Reuters

Ionis announces positive topline results from Phase 3 OASIS-HAE study of investigational donidalorsen in patients with hereditary angioedema

Donidalorsen met the primary endpoint with a statistically significant reduction in the rate of HAE attacks in patients treated every 4 weeks or patients treated every 8 weeks  Donidalorsen demonstrat...

3 months ago - PRNewsWire

Ionis poised for continued momentum in 2024 with product launches and key advances in robust pipeline of investigational medicines for serious diseases

– Numerous value-driving commercial, regulatory and pipeline milestones anticipated – CARLSBAD, Calif. , Jan. 8, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced highlig...

3 months ago - PRNewsWire

Ionis Pharmaceuticals, AstraZeneca get FDA approval for rare genetic disease treatment

Ionis Pharmaceuticals IONS, +1.61% and AstraZeneca's AZN, +0.79% Wainua has been approved by the U.S. Food and Drug Administration for treating a symptom of a rare genetic disease.

Other symbols: AZN
4 months ago - Market Watch

WAINUA™ (eplontersen) granted regulatory approval in the U.S. for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis

U.S. FDA approval based on Phase 3 NEURO-TTRansform results showing WAINUA demonstrated consistent and sustained benefit halting neuropathy disease progression and improving neuropathy impairment and ...

4 months ago - PRNewsWire

US FDA approves Ionis-AstraZeneca's nerve disease drug

The U.S. Food and Drug Administration (FDA) on Thursday approved Ionis Pharmaceuticals and partner AstraZeneca's drug to treat nerve damage caused by a life-shortening rare disease.

Other symbols: AZN
4 months ago - Reuters

Ionis to present at 42nd Annual J.P. Morgan Healthcare Conference

CARLSBAD, Calif. , Dec. 20, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that Brett P.

4 months ago - PRNewsWire

Ionis announces European licensing agreement with Otsuka for donidalorsen in hereditary angioedema

Otsuka to leverage strong commercial infrastructure and rare disease experience to reach European HAE patients Ionis plans to independently bring donidalorsen to U.S. patients if approved Donidalorsen...

4 months ago - PRNewsWire

Ionis announces the appointment of Michael Yang to Board of Directors

CARLSBAD, Calif. , Dec. 14, 2023 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced the appointment of Michael Yang, an experienced biopharmaceutical executive, to the Ionis Bo...

4 months ago - PRNewsWire

Ionis shares positive clinical update from ongoing trial of ION582 for Angelman syndrome

Part 1 of HALOS trial evaluating ION582 has completed enrollment with results expected in mid-2024 ION582 has been generally well tolerated at all dose levels, and participants are continuing to Part ...

5 months ago - PRNewsWire

Ionis presents positive two-year results from the Phase 2 open label extension study of donidalorsen in patients with hereditary angioedema

Continued treatment over two years with donidalorsen demonstrated sustained reduction in hereditary angioedema attacks and improved quality of life Donidalorsen recently received orphan drug designati...

5 months ago - PRNewsWire

Ionis reports third quarter 2023 financial results

Olezarsen Phase 3 data showed significant triglyceride lowering, substantial reductions in acute pancreatitis attacks and favorable safety and tolerability in patients with FCS; on track for regulator...

6 months ago - PRNewsWire

Ionis to hold third quarter 2023 financial results webcast

Webcast scheduled for Thursday, November 2 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

6 months ago - PRNewsWire