SHISX Holdings List

As of Apr 30, 2025

No.	Symbol	Name	% Weight	Shares
1	LLY	Eli Lilly and Company	12.10%	929,918
2	BSX	Boston Scientific Corporation	6.06%	4,073,041
3	ABBV	AbbVie Inc.	5.85%	2,072,351
4	ABT	Abbott Laboratories	4.93%	2,604,639
5	UNH	UnitedHealth Group Incorporated	4.27%	717,618
6	SYK	Stryker Corporation	3.64%	672,262
7	TSTXX	BlackRock Liquidity Funds - T-Fund	3.47%	239,678,258
8	JNJ	Johnson & Johnson	3.45%	1,527,005
9	AMGN	Amgen Inc.	2.89%	687,406
10	ISRG	Intuitive Surgical, Inc.	2.85%	381,710
11	MCK	McKesson Corporation	2.50%	242,676
12	MDT	Medtronic plc	2.44%	1,992,642
13	COR	Cencora, Inc.	2.44%	577,086
14	EW	Edwards Lifesciences Corporation	2.15%	1,967,269
15	VRTX	Vertex Pharmaceuticals Incorporated	2.14%	290,380
16	ARGX	argenx SE	1.98%	211,620
17	ALNY	Alnylam Pharmaceuticals, Inc.	1.91%	500,576
18	GILD	Gilead Sciences, Inc.	1.74%	1,125,322
19	ELV	Elevance Health, Inc.	1.70%	279,607
20	TMO	Thermo Fisher Scientific Inc.	1.66%	267,577
21	BMY	Bristol-Myers Squibb Company	1.66%	2,279,200
22	DHR	Danaher Corporation	1.55%	536,402
23	BDX	Becton, Dickinson and Company	1.49%	495,640
24	MRK	Merck & Co., Inc.	1.35%	1,097,361
25	REGN	Regeneron Pharmaceuticals, Inc.	1.25%	144,734
26	CI	The Cigna Group	1.10%	222,702
27	ZTS	Zoetis Inc.	0.96%	422,297
28	WAT	Waters Corporation	0.91%	180,790
29	PFE	Pfizer Inc.	0.85%	2,395,660
30	CVS	CVS Health Corporation	0.79%	815,115
31	DGX	Quest Diagnostics Incorporated	0.78%	303,566
32	INSM	Insmed Incorporated	0.69%	658,178
33	PEN	Penumbra, Inc.	0.68%	161,467
34	TEVA	Teva Pharmaceutical Industries Limited	0.68%	3,047,795
35	LON: AZN	AstraZeneca PLC	0.67%	324,659
36	RYTM	Rhythm Pharmaceuticals, Inc.	0.65%	690,347
37	SWX: ALC	Alcon Inc.	0.63%	443,060
38	HUM	Humana Inc.	0.56%	146,579
39	IDXX	IDEXX Laboratories, Inc.	0.54%	86,759
40	SWX: ROG	Roche Holding AG	0.53%	111,346
41	EPA: SAN	Sanofi	0.52%	328,294
42	BIIB	Biogen Inc.	0.44%	253,388
43	WST	West Pharmaceutical Services, Inc.	0.41%	134,864
44	NUVL	Nuvalent, Inc.	0.41%	367,660
45	HCA	HCA Healthcare, Inc.	0.41%	81,353
46	COO	The Cooper Companies, Inc.	0.41%	343,632
47	LH	Labcorp Holdings Inc.	0.37%	105,168
48	DXCM	DexCom, Inc.	0.36%	351,585
49	RGEN	Repligen Corporation	0.33%	167,659
50	NTRA	Natera, Inc.	0.33%	151,876
51	ASND	Ascendis Pharma A/S	0.31%	124,134
52	EBR: UCB	UCB SA	0.30%	111,585
53	TYO: 4568	Daiichi Sankyo Company, Limited	0.29%	781,700
54	GEHC	GE HealthCare Technologies Inc.	0.27%	268,721
55	EXAS	Exact Sciences Corporation	0.27%	413,015
56	ALGN	Align Technology, Inc.	0.27%	107,478
57	BPMC	Blueprint Medicines Corporation	0.27%	204,909
58	GKOS	Glaukos Corporation	0.26%	190,433
59	BMRN	BioMarin Pharmaceutical Inc.	0.26%	281,157
60	STE	STERIS plc	0.25%	75,548
61	PODD	Insulet Corporation	0.24%	66,855
62	MTD	Mettler-Toledo International Inc.	0.24%	15,479
63	NBIX	Neurocrine Biosciences, Inc.	0.23%	144,705
64	GH	Guardant Health, Inc.	0.22%	323,016
65	IQV	IQVIA Holdings Inc.	0.20%	88,638
66	PTCT	PTC Therapeutics, Inc.	0.20%	274,700
67	ACLX	Arcellx, Inc.	0.19%	207,201
68	EXEL	Exelixis, Inc.	0.19%	342,550
69	XENE	Xenon Pharmaceuticals Inc.	0.18%	330,873
70	PTGX	Protagonist Therapeutics, Inc.	0.17%	262,826
71	MRNA	Moderna, Inc.	0.17%	407,880
72	NVCR	NovoCure Limited	0.17%	641,675
73	TECH	Bio-Techne Corporation	0.16%	219,569
74	MRUS	Merus N.V.	0.15%	230,676
75	INCY	Incyte Corporation	0.15%	160,906
76	INSP	Inspire Medical Systems, Inc.	0.14%	58,973
77	HLXB	Helix Acquisition Corp. II	0.13%	850,715
78	HOLX	Hologic, Inc.	0.13%	156,655
79	STOK	Stoke Therapeutics, Inc.	0.13%	925,936
80	BBIO	BridgeBio Pharma, Inc.	0.13%	231,965
81	n/a	PROJECT LRN SERIES B Prvt	0.13%	386,520
82	ROIV	Roivant Sciences Ltd.	0.13%	757,759
83	n/a	USD - OTHER PAYABLES/RECEIVABLES	0.10%	7,126,410
84	n/a	Kartos Therapeutics Series C Prvt	0.10%	1,233,856
85	n/a	PROJECT QAT - SERIES D Prvt	0.10%	80,024,425
86	CPH: ZEAL	Zealand Pharma A/S	0.09%	92,335
87	n/a	Adarx Pharmaceuticals Series C Prvt	0.09%	769,230
88	SMMT	Summit Therapeutics Inc.	0.08%	227,720
89	BHVN	Biohaven Ltd.	0.07%	230,982
90	GPCR	Structure Therapeutics Inc.	0.07%	187,318
91	n/a	PROJECT TARGET SERIES C Prvt	0.07%	592,636
92	BNTX	BioNTech SE	0.07%	47,467
93	LEGN	Legend Biotech Corporation	0.07%	140,057
94	ALKS	Alkermes plc	0.07%	169,810
95	n/a	Genesis Therapeutics Series B Prvt	0.07%	823,870
96	IRON	Disc Medicine, Inc.	0.07%	96,722
97	IONS	Ionis Pharmaceuticals, Inc.	0.07%	155,518
98	EWTX	Edgewise Therapeutics, Inc.	0.07%	286,215
99	DNLI	Denali Therapeutics Inc.	0.06%	269,381
100	DYN	Dyne Therapeutics, Inc.	0.06%	322,438
101	BEAM	Beam Therapeutics Inc.	0.05%	187,715
102	MTSR	Metsera, Inc.	0.05%	152,727
103	PCVX	Vaxcyte, Inc.	0.05%	102,708
104	VKTX	Viking Therapeutics, Inc.	0.05%	118,964
105	SRRK	Scholar Rock Holding Corporation	0.05%	103,615
106	MLTX	MoonLake Immunotherapeutics	0.05%	77,153
107	EBR: NYXH	Nyxoah SA	0.03%	392,838
108	RGNX	REGENXBIO Inc.	0.03%	247,495
109	ALLO	Allogene Therapeutics, Inc.	0.03%	1,413,527
110	n/a	Helix Acq Corp Pipe Commitment Prvt	0.03%	224,300
111	KYMR	Kymera Therapeutics, Inc.	0.03%	60,530
112	WVE	Wave Life Sciences Ltd.	0.03%	252,070
113	n/a	Kartos Therapeutics Series D Prvt	0.03%	339,469
114	CGON	CG Oncology, Inc.	0.03%	68,649
115	n/a	PROJECT CLA COMMON Prvt	0.03%	858,333
116	VIR	Vir Biotechnology, Inc.	0.02%	272,240
117	VYGR	Voyager Therapeutics, Inc.	0.02%	425,922
118	n/a	PROJECT K SERIES B Prvt	0.02%	3,518,800
119	AUTL	Autolus Therapeutics plc	0.02%	850,117
120	n/a	Affinivax Milestone Placeholder Prvt	0.02%	122,824
121	TCRX	TScan Therapeutics, Inc.	0.02%	650,525
122	OBIO	Orchestra BioMed Holdings, Inc.	0.01%	250,564
123	n/a	Icash	0.01%	694,479
124	PRTA	Prothena Corporation plc	0.01%	69,900
125	n/a	Exo Conv Bridge Note Prvt	0.01%	541,368
126	n/a	Abiomed Cvrs	0.01%	243,643
127	FDMT	4D Molecular Therapeutics, Inc.	0.01%	154,258
128	ACIU	AC Immune SA	0.00%	115,866
129	n/a	Carbon Health Convertible Note Prvt	0.00%	1,209
130	n/a	Mirati Therapeutics Inc	0.00%	228,510
131	n/a	JPY - Other Payables/Receivables	0.00%	21,105,900
132	n/a	PROJECT CRO SERIES D2 Prvt	0.00%	1,670,499
133	n/a	EUR - Spendable Cash	0.00%	108,572
134	n/a	EUR/USD Purchased	0.00%	123,242
135	NUVB.WS	Nuvation Bio ([Wts/Rts])	0.00%	77,354
136	n/a	Exo Series C Pref Eq Prvt	0.00%	1,908,330
137	n/a	PROJECT IBA COMMON Prvt	0.00%	1,700
138	n/a	Afferent Contingent Payment Placeh Prvt	0.00%	3,420,640
139	n/a	Korro Bio Inc Cvr	0.00%	428,010
140	n/a	Caremax ([Wts/Rts])	0.00%	88,432
141	n/a	NOK - Spendable Cash	0.00%	891
142	n/a	GBP - Spendable Cash	0.00%	59
143	n/a	HKD - Spendable Cash	0.00%	265
144	n/a	AUD - Spendable Cash	0.00%	1
145	n/a	EUR/USD Sold	0.00%	123,242
146	n/a	EUR/USD Sold	0.00%	108,572
147	n/a	EUR/USD Purchased	-0.00%	108,572
148	n/a	USD - Spendable Cash	-1.17%	81,110,629

As of Apr 30, 2025

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Asset Allocation

Asset Class	% Weight
Stocks	97.17%
Cash	2.41%
Other	0.40%
Bond	0.01%

Sector Breakdown

Sector	% Weight
Health Care	91.41%
Other	8.59%

Country Breakdown

Sector	% Weight
United States	87.03%
Other	6.27%
Ireland	2.47%
United Kingdom	1.33%
Switzerland	1.02%
Japan	0.59%
France	0.35%
China	0.26%
Canada	0.19%
Netherlands	0.18%
Denmark	0.17%
Jersey	0.14%