Lyra Therapeutics, Inc. (LYRA)

OTCMKTS · Delayed Price · Currency is USD
0.6500
-0.0500 (-7.14%)
At close: May 18, 2026
Market Cap1.15M -84.3%
Revenue (ttm)398.00K -74.1%
Net Income-28.92M
EPS-18.62
Shares Out1.77M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume6,179
Average Volume8,679
Open0.7000
Previous Close0.7000
Day's Range0.6500 - 0.7000
52-Week Range0.3100 - 37.5000
Beta0.69
RSI39.53
Earnings DateAug 7, 2026

About Lyra Therapeutics

Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company’s product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical trial for the treatment of chronic rhinosinusitis (CRS); and LYR-220 for CRS patients wh... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2005
Employees 27
Stock Exchange OTCMKTS
Ticker Symbol LYRA
Full Company Profile

Financial Performance

In 2025, Lyra Therapeutics's revenue was $398,000, a decrease of -74.05% compared to the previous year's $1.53 million. Losses were -$28.92 million, -69.05% less than in 2024.

Financial Statements

News

Lyra Therapeutics announces intention to file Form 25 for delisting from Nasdaq

Lyra Therapeutics (LYRA) announced its intention to voluntarily file a Form 25 Notification of Delisting with the U.S. Securities and Exchange Commission on Monday, April 20, 2026, to remove its…

4 weeks ago - TheFly

Lyra Therapeutics, Inc. Announces Intention to Voluntarily File Form 25 for Delisting from Nasdaq and Subsequent Deregistration with the SEC

WATERTOWN, Mass., April 17, 2026 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (the "Company") today announced its intention to voluntarily file a Form 25 Notification of Delisting with the U.S. Securit...

4 weeks ago - GlobeNewsWire

Lyra Therapeutics common stock to be delisted by Nasdaq

On February 2, Lyra Therapeutics (LYRA) received a letter from the Listing Qualifications Department of The Nasdaq Stock Market notifying the company that Nasdaq has determined to delist the company’s...

3 months ago - TheFly

Why Is Lyra Therapeutics Stock (LYRA) Down Today?

Lyra Therapeutics stock was down on Monday after the company revealed a pause to its operations.

4 months ago - TipRanks

Lyra Therapeutics suspends further development of LYR-210

Lyra Therapeutics (LYRA), announced that its Board of Directors has decided to suspend further development of LYR-210, the Company’s lead product candidate for the treatment of chronic rhinosinusitis....

4 months ago - TheFly

Lyra Therapeutics Provides Corporate Update

WATERTOWN, Mass., Jan. 12, 2026 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”) today announced that its Board of Directors has decided to suspend further developm...

4 months ago - GlobeNewsWire

Lyra Therapeutics reports Q3 EPS ($3.38), consensus ($4.07)

Reports Q3 revenue $25,000, consensus $154,250. “We are now focused on putting all the components in place for a new, confirmatory Phase 3 clinical trial to make progress toward a…

6 months ago - TheFly

Lyra Therapeutics Reports Third Quarter 2025 Financial Results and Provides Corporate Update

– Company plans new, confirmatory Phase 3 clinical trial of LYR-210 for treatment of chronic rhinosinusitis (CRS) without nasal polyps, on path to NDA submission –

6 months ago - GlobeNewsWire

Lyra Therapeutics announces clinical plan for LYR-210

Lyra Therapeutics (LYRA) announced the Company’s clinical plan and upcoming oral presentation of results from the positive Phase 3 ENLIGHTEN 2 trial for LYR-210, the company’s lead product candidate f...

8 months ago - TheFly

Lyra Therapeutics Announces Clinical Plan for LYR-210 and Late-Breaking Oral Presentation of Phase 3 ENLIGHTEN 2 Study

Company outlines clinical plan for LYR-210 based on FDA meeting on the path to NDA submission  Positive ENLIGHTEN 2 results highlighted at the AAO-HNS 2025 Annual Meeting WATERTOWN, Mass., Oct. 06, 20...

8 months ago - GlobeNewsWire

Lyra Therapeutics reports Q2 EPS ($5.51), consensus ($4.78)

Reports Q2 revenue $183,000, consensus $181,250. “The positive results from our ENLIGHTEN 2 trial have enabled us to secure financing and are providing momentum to optimize our regulatory strategy and...

9 months ago - TheFly

Lyra Therapeutics Reports Second Quarter 2025 Financial Results and Provides Corporate Update

– Positive ENLIGHTEN 2 Phase 3 results announced in June 2025 propel business activities in manufacturing, regulatory strategy and ENLIGHTEN clinical dataset analysis to advance path forward for LYR-2...

9 months ago - GlobeNewsWire

Lyra Therapeutics files to sell 846,744 shares of common stock for holders

17:16 EDT Lyra Therapeutics (LYRA) files to sell 846,744 shares of common stock for holders

10 months ago - TheFly

Lyra Therapeutics Announces Up to Approximately $15 Million Registered Direct Offering and Concurrent Private Placement Priced At-The-Market Under Nasdaq Rules

Upfront Gross Proceeds of $5.0 Million, with Up to Approximately $9.8 Million of Additional Gross Proceeds Assuming the Cash Exercise in Full of Private Placement Warrants Upfront Gross Proceeds of $5...

11 months ago - GlobeNewsWire

Lyra Therapeutics target adjusted to $16 from $2 at H.C. Wainwright

H.C. Wainwright raised the firm’s price target on Lyra Therapeutics (LYRA) to $16 from $2 and keeps a Neutral rating on the shares following the company’s reverse stock split. Published…

1 year ago - TheFly

Lyra Therapeutics Stock (LYRA) Rockets 530% on Phase 3 Trial Results

Lyra Therapeutics stock took off on Monday as investors reacted to positive Phase 3 clinical trial results.

1 year ago - TipRanks

Lyra Therapeutics Transcript: Study Result

Enlightened II phase III trial of LYR-210 in CRS met primary and key secondary endpoints, showing significant symptom and quality-of-life improvements with a strong safety profile. Plans are underway for FDA engagement and further studies in polyp patients.

1 year ago - Transcripts

Lyra Therapeutics says ENLIGHTEN 2 trial of LYR-210 met primary endpoint

Lyra Therapeutics (LYRA) announced results from the ENLIGHTEN 2 Phase 3 clinical trial of LYR-210 in adult patients with CRS. The ENLIGHTEN 2 trial met its primary endpoint, with LYR-210…

1 year ago - TheFly

Lyra Therapeutics Reports Positive Results from the ENLIGHTEN 2 Phase 3 Trial of LYR-210 Achieving Statistically Significant Results for Primary and Key Secondary Endpoints in the Treatment of Chronic Rhinosinusitis (CRS)

WATERTOWN, Mass., June 02, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory s...

1 year ago - GlobeNewsWire

Lyra Therapeutics trading halted, news pending

19:50 EDT Lyra Therapeutics (LYRA) trading halted, news pending

1 year ago - TheFly

Lyra Therapeutics to present results from ENLIGHTEN 1 Phase 3 study

Lyra Therapeutics (LYRA) announced that the Company plans to present results from the 52-week Extension Stage of the ENLIGHTEN 1 Phase 3 study for LYR-210, the Company’s lead product candidate…

1 year ago - TheFly

Lyra Therapeutics to Present 52-week Extension Stage Results for ENLIGHTEN 1 Phase 3 Study for LYR-210 for the Treatment of Chronic Rhinosinusitis at COSM 2025

WATERTOWN, Mass., May 07, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA), (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory s...

1 year ago - GlobeNewsWire

Lyra Therapeutics Reports First Quarter 2025 Financial Results and Provides Corporate Update

– Phase 3 results from ENLIGHTEN 2 pivotal Phase 3 trial of LYR 210 in Chronic Rhinosinusitis (CRS) expected in Q2 2025 – – Phase 3 results from ENLIGHTEN 2 pivotal Phase 3 trial of LYR 210 in Chronic...

1 year ago - GlobeNewsWire

Lyra Therapeutics reports Q4 EPS ($1.43), consensus (13c)

Cash and cash equivalents as of December 31 were $40.6M compared with cash, cash equivalents and short-term investments of $51.6M at September 30. Based on our current business plan, we…

1 year ago - TheFly

Lyra Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update

WATERTOWN, Mass., March 13, 2025 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc.  (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory...

1 year ago - GlobeNewsWire