Regulus Therapeutics Ratios and Metrics

Market cap in millions JPY. Fiscal year is January - December.

Millions JPY. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Jul '25 Jul 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020
Market Capitalization	2,825	3,693	3,299	1,225	-	-
Market Cap Growth	11.97%	11.97%	169.24%	-	-	-
Enterprise Value	2,014	3,054	2,612	881	-	-
Last Close Price	1216.00	1590.00	1420.00	529.00	-	-
PE Ratio	53.29	69.69	32.34	10.94	-	-
PS Ratio	0.35	0.45	0.93	0.38	-	-
PB Ratio	2.16	2.83	2.73	1.12	-	-
P/TBV Ratio	51.36	67.15	4.12	1.69	-	-
P/FCF Ratio	6.97	9.12	113.75	5.30	-	-
P/OCF Ratio	6.77	8.86	62.24	5.06	-	-
EV/Sales Ratio	0.25	0.37	0.74	0.27	-	-
EV/EBITDA Ratio	7.22	10.95	10.97	3.26	-	-
EV/EBIT Ratio	14.08	21.36	16.85	4.47	-	-
EV/FCF Ratio	4.97	7.54	90.06	3.82	-	-
Debt / Equity Ratio	0.92	0.92	0.28	0.22	0.32	0.43
Debt / EBITDA Ratio	4.32	4.32	1.42	0.91	-	-
Debt / FCF Ratio	2.97	2.97	11.69	1.06	-	-
Asset Turnover	2.22	2.22	1.75	1.92	2.05	-
Quick Ratio	1.12	1.12	2.21	2.02	1.55	1.49
Current Ratio	1.18	1.18	2.31	2.10	1.64	1.56
Return on Equity (ROE)	4.21%	4.21%	8.85%	12.06%	22.71%	-
Return on Assets (ROA)	2.43%	2.43%	4.78%	7.23%	9.15%	-
Return on Capital (ROIC)	4.40%	4.40%	6.71%	10.48%	13.91%	-
Return on Capital Employed (ROCE)	6.30%	6.30%	10.60%	16.00%	23.60%	24.50%
Earnings Yield	1.88%	1.44%	3.09%	9.14%	-	-
FCF Yield	14.34%	10.96%	0.88%	18.86%	-	-
Buyback Yield / Dilution	-0.01%	-0.01%	-17.51%	-0.54%	-2.34%	-

Source: S&P Global Market Intelligence. Standard template. Financial Sources.