Protagonist Therapeutics, Inc. (PTGX)

NASDAQ: PTGX · Real-Time Price · USD
112.46
+2.68 (2.44%)
Jun 15, 2026, 4:00 PM EDT - Market closed
Market Cap7.23B +145.2%
Revenue (ttm)74.06M -64.4%
Net Income-114.71M
EPS-1.79
Shares Out 64.31M
PE Ration/a
Forward PE32.57
Dividendn/a
Ex-Dividend Daten/a
Volume536,301
Open109.10
Previous Close109.78
Day's Range109.10 - 112.77
52-Week Range49.38 - 112.77
Beta1.83
AnalystsStrong Buy
Price Target118.69 (+5.54%)
Earnings DateMay 5, 2026

About PTGX

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class or... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Aug 11, 2016
Employees 131
Stock Exchange NASDAQ
Ticker Symbol PTGX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 13 analysts, the average rating for PTGX stock is "Strong Buy." The 12-month stock price target is $118.69, which is an increase of 5.54% from the latest price.

Price Target
$118.69
(5.54% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Protagonist Therapeutics Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

The company is advancing as a commercial-stage biotech with strong financials, highlighted by Icotyde's successful launch and anticipated Rusfertide approval. Its robust, de-risked pipeline includes innovative oral peptides for I&I and obesity, with strategic partnerships and shareholder rewards planned.

5 days ago - Transcripts

Protagonist Therapeutics Transcript: Jefferies Global Healthcare Conference 2026

Strong royalty streams from major partnerships and a robust, de-risked pipeline support self-funded R&D and potential share buybacks. ICOTYDE is positioned for major growth, while rusfertide's opt-out deal secures significant payments and high royalties. Multiple innovative programs advance toward key milestones.

12 days ago - Transcripts

Protagonist Therapeutics to Present Phase 3 VERIFY and Long-Term Rusfertide Data at the 2026 European Hematology Association Congress

NEWARK, CA / ACCESS Newswire / June 1, 2026 / Protagonist Therapeutics, Inc. ("Protagonist" or the "Company") today announced that four abstracts highlighting rusfertide in polycythemia vera (PV) will...

14 days ago - Accesswire

Protagonist Therapeutics Slides: Company presentation

Protagonist Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on June 1, 2026.

14 days ago - Filings

Protagonist Therapeutics to Participate in Two Investment Bank Conferences in June 2026

NEWARK, CA / ACCESS Newswire / May 28, 2026 / Protagonist Therapeutics (Nasdaq:PTGX) ("Protagonist" or "the Company") today announced that Dinesh V. Patel, Ph.D.

18 days ago - Accesswire

Protagonist Therapeutics price target raised to $130 from $125 at Citi

Citi raised the firm’s price target on Protagonist Therapeutics (PTGX) to $130 from $125 and keeps a Buy rating on the shares. The firm updated the company’s model post the…

5 weeks ago - TheFly

Protagonist Therapeutics price target raised to $137 from $120 at Citizens

Citizens analyst Jonathan Wolleben raised the firm’s price target on Protagonist Therapeutics (PTGX) to $137 from $120 and keeps an Outperform rating on the shares. Protagonist Therapeutics is expecte...

5 weeks ago - TheFly

Protagonist Therapeutics price target raised to $110 from $97 at Goldman Sachs

Goldman Sachs raised the firm’s price target on Protagonist Therapeutics (PTGX) to $110 from $97 and keeps a Neutral rating on the shares. The price target increase is driven mainly…

5 weeks ago - TheFly

Protagonist Therapeutics management to meet virtually with Clear Street

Virtual Meeting to be held on May 12-13 hosted by Clear Street.

5 weeks ago - TheFly

Protagonist Therapeutics participates in a conference call with JPMorgan

Conference call with management will be held on May 6 at 2 pm hosted by JPMorgan.Webcast Link

5 weeks ago - TheFly

Protagonist Reports First Quarter 2026 Financial Results and Provides Corporate Update

ICOTYDE™ (icotrokinra) approved by FDA in March for moderate-to-severe plaque psoriasis, triggering a $50 million milestone payment; Protagonist receives tiered royalties of 6% to 10% and is eligible ...

5 weeks ago - Accesswire

Protagonist Therapeutics Earnings release: Q1 2026

Protagonist Therapeutics released its Q1 2026 earnings on May 5, 2026, summarizing the period's financial results.

5 weeks ago - Filings

Protagonist Therapeutics Quarterly report: Q1 2026

Protagonist Therapeutics has published its Q1 2026 quarterly earnings report on May 5, 2026.

5 weeks ago - Filings

Protagonist exercises right to opt out of 50:50 U.S. arrangement for rusfertide

Protagonist Therapeutics (PTGX) announced that it has exercised its right to opt out of the 50:50 U.S. profit and loss sharing arrangement under its worldwide license and collaboration agreement with…

Other symbols: TAK
6 weeks ago - TheFly

Protagonist Exercises Rusfertide U.S. Opt-Out Right Under Takeda Collaboration

Opt-out election makes Protagonist eligible for $200 million upon exercise and an additional $200 million upon FDA approval of rusfertide for polycythemia vera Approval would also trigger a $75 millio...

6 weeks ago - Accesswire

Protagonist Therapeutics Proxy statement: Proxy filing

Protagonist Therapeutics filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Protagonist Therapeutics Proxy statement: Proxy filing

Protagonist Therapeutics filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Protagonist Therapeutics Reports Granting of Inducement Awards

NEWARK, CA / ACCESS Newswire / April 16, 2026 / Protagonist Therapeutics, Inc. (Nasdaq:PTGX) today reported that on April 15, 2026, it issued inducement awards to two recently hired employees in accor...

2 months ago - Accesswire

Protagonist Therapeutics price target raised to $121 from $110 at Truist

Truist analyst Srikripa Devarakonda raised the firm’s price target on Protagonist Therapeutics (PTGX) to $121 from $110 and keeps a Buy rating on the shares. The firm is citing strong…

Other symbols: JNJ
2 months ago - TheFly

Protagonist Therapeutics price target raised to $121 from $110 at Truist

Truist analyst Srikripa Devarakonda raised the firm’s price target on Protagonist Therapeutics (PTGX) to $121 from $110 and keeps a Buy rating on the shares. Following J&J’s (JNJ) commentary on…

Other symbols: JNJ
2 months ago - TheFly

Protagonist Therapeutics price target raised to $116 from $104 at Clear Street

Clear Street analyst Kaveri Pohlman raised the firm’s price target on Protagonist Therapeutics (PTGX) to $116 from $104 and keeps a Buy rating on the shares. Following management meetings, the…

2 months ago - TheFly

Protagonist Announces Presentation of One-Year Phase 3 Data for ICOTYDE(TM) in Moderate-to-Severe Plaque Psoriasis at the 2026 American Academy of Dermatology (AAD) Annual Meeting

One-year Phase 3 data for ICOTYDE to be presented at AAD 2026 demonstrate lasting skin clearance and a favorable safety profile in a once daily pill for moderate-to-severe plaque psoriasis Results fur...

2 months ago - Accesswire

Protagonist price target raised to $110 from $107 at Leerink

Leerink analyst Faisal Khurshid raised the firm’s price target on Protagonist Therapeutics (PTGX) to $110 from $107 and keeps an Outperform rating on the shares. The firm is “impressed” with…

3 months ago - TheFly

Protagonist Therapeutics price target raised to $120 from $112 at Citizens

Citizens raised the firm’s price target on Protagonist Therapeutics (PTGX) to $120 from $112 and keeps an Outperform rating on the shares. The firm says Icotyde’s approval represents a “meaningful…

3 months ago - TheFly

Protagonist Therapeutics price target raised to $112 from $100 at Wedbush

Wedbush raised the firm’s price target on Protagonist Therapeutics (PTGX) to $112 from $100 and keeps an Outperform rating on the shares. The firm believes the FDA approval of Icotyde…

3 months ago - TheFly