Protagonist Therapeutics, Inc. (PTGX)

NASDAQ: PTGX · Real-Time Price · USD

146.92

-0.83 (-0.56%)

Sep 1, 2026, 12:40 PM EDT - Market open

Protagonist Therapeutics Financials Overview

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Revenue & Profits

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Revenue	281.99	46.02	434.43	60	26.58	27.36
Revenue Growth	34.81%	-89.41%	624.05%	125.72%	-2.84%	-4.44%
Gross Profit	281.99	46.02	434.43	60	26.58	27.36
Operating Income	58.34	-158.13	252.84	-93.65	-131.37	-125.85
Net Income	82.91	-130.15	275.19	-78.96	-127.39	-125.55
Earnings Per Share	1.22	-2.05	4.23	-1.39	-2.60	-2.71
EPS Growth	51.80%	-	-	-	-	-

Cash & Debt

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Cash & Investments	849.45	646	559.17	341.62	237.36	326.9
Total Debt	9.22	10.32	10.87	1.14	3.66	5.86
Net Cash (Debt)	840.24	635.68	548.3	340.48	233.7	321.04
Net Cash Growth	26.98%	15.94%	61.04%	45.69%	-27.21%	6.36%
Net Cash Per Share	12.47	10.00	8.43	6.00	4.77	6.93

Cash Flow & CapEx

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Operating Cash Flow	131.2	57.67	184.15	-70.24	-108.14	-107.87
Capital Expenditures	-0.62	-1.59	-1.36	-0.61	-0.8	-1.1
Free Cash Flow	130.58	56.08	182.8	-70.85	-108.93	-108.97
Free Cash Flow Growth	251.98%	-69.32%	-	-	-	-

Margins

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Jun '26 Jun 30, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Gross Margin	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%
Operating Margin	20.69%	-343.63%	58.20%	-156.09%	-494.24%	-460.01%
Pretax Margin	29.91%	-281.01%	64.32%	-131.59%	-479.26%	-458.94%
Profit Margin	29.40%	-282.83%	63.34%	-131.59%	-479.26%	-458.94%
FCF Margin	46.31%	121.87%	42.08%	-118.08%	-409.81%	-398.31%

Valuation

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Sep '26 Sep 1, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
PE Ratio	120.35	-	8.36	-	-	-
Forward PE	71.63	59.76	36.33	-	-	-
P/FCF Ratio	73.22	97.36	12.59	-	-	-
PS Ratio	33.90	118.66	5.30	22.04	20.19	59.67