Protagonist Therapeutics, Inc. (PTGX)

NASDAQ: PTGX · Real-Time Price · USD
100.40
-1.81 (-1.77%)
May 28, 2026, 2:30 PM EDT - Market open
Market Cap6.46B +130.1%
Revenue (ttm)74.06M -64.4%
Net Income-114.71M
EPS-1.79
Shares Out 64.31M
PE Ration/a
Forward PE29.61
Dividendn/a
Ex-Dividend Daten/a
Volume310,321
Open102.74
Previous Close102.21
Day's Range99.43 - 103.71
52-Week Range45.28 - 107.84
Beta1.88
AnalystsStrong Buy
Price Target118.69 (+18.22%)
Earnings DateMay 5, 2026

About PTGX

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class or... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Aug 11, 2016
Employees 131
Stock Exchange NASDAQ
Ticker Symbol PTGX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 13 analysts, the average rating for PTGX stock is "Strong Buy." The 12-month stock price target is $118.69, which is an increase of 18.22% from the latest price.

Price Target
$118.69
(18.22% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Protagonist Therapeutics to Participate in Two Investment Bank Conferences in June 2026

NEWARK, CA / ACCESS Newswire / May 28, 2026 / Protagonist Therapeutics (Nasdaq:PTGX) ("Protagonist" or "the Company") today announced that Dinesh V. Patel, Ph.D.

7 hours ago - Accesswire

Protagonist Therapeutics price target raised to $130 from $125 at Citi

Citi raised the firm’s price target on Protagonist Therapeutics (PTGX) to $130 from $125 and keeps a Buy rating on the shares. The firm updated the company’s model post the…

18 days ago - TheFly

Protagonist Therapeutics price target raised to $137 from $120 at Citizens

Citizens analyst Jonathan Wolleben raised the firm’s price target on Protagonist Therapeutics (PTGX) to $137 from $120 and keeps an Outperform rating on the shares. Protagonist Therapeutics is expecte...

21 days ago - TheFly

Protagonist Therapeutics price target raised to $110 from $97 at Goldman Sachs

Goldman Sachs raised the firm’s price target on Protagonist Therapeutics (PTGX) to $110 from $97 and keeps a Neutral rating on the shares. The price target increase is driven mainly…

21 days ago - TheFly

Protagonist Therapeutics management to meet virtually with Clear Street

Virtual Meeting to be held on May 12-13 hosted by Clear Street.

21 days ago - TheFly

Protagonist Therapeutics participates in a conference call with JPMorgan

Conference call with management will be held on May 6 at 2 pm hosted by JPMorgan.Webcast Link

21 days ago - TheFly

Protagonist Reports First Quarter 2026 Financial Results and Provides Corporate Update

ICOTYDE™ (icotrokinra) approved by FDA in March for moderate-to-severe plaque psoriasis, triggering a $50 million milestone payment; Protagonist receives tiered royalties of 6% to 10% and is eligible ...

22 days ago - Accesswire

Protagonist Therapeutics Earnings release: Q1 2026

Protagonist Therapeutics released its Q1 2026 earnings on May 5, 2026, summarizing the period's financial results.

22 days ago - Filings

Protagonist Therapeutics Quarterly report: Q1 2026

Protagonist Therapeutics has published its Q1 2026 quarterly earnings report on May 5, 2026.

22 days ago - Filings

Protagonist exercises right to opt out of 50:50 U.S. arrangement for rusfertide

Protagonist Therapeutics (PTGX) announced that it has exercised its right to opt out of the 50:50 U.S. profit and loss sharing arrangement under its worldwide license and collaboration agreement with…

Other symbols: TAK
4 weeks ago - TheFly

Protagonist Exercises Rusfertide U.S. Opt-Out Right Under Takeda Collaboration

Opt-out election makes Protagonist eligible for $200 million upon exercise and an additional $200 million upon FDA approval of rusfertide for polycythemia vera Approval would also trigger a $75 millio...

4 weeks ago - Accesswire

Protagonist Therapeutics Proxy statement: Proxy filing

Protagonist Therapeutics filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Protagonist Therapeutics Proxy statement: Proxy filing

Protagonist Therapeutics filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Protagonist Therapeutics Reports Granting of Inducement Awards

NEWARK, CA / ACCESS Newswire / April 16, 2026 / Protagonist Therapeutics, Inc. (Nasdaq:PTGX) today reported that on April 15, 2026, it issued inducement awards to two recently hired employees in accor...

5 weeks ago - Accesswire

Protagonist Therapeutics price target raised to $121 from $110 at Truist

Truist analyst Srikripa Devarakonda raised the firm’s price target on Protagonist Therapeutics (PTGX) to $121 from $110 and keeps a Buy rating on the shares. The firm is citing strong…

Other symbols: JNJ
6 weeks ago - TheFly

Protagonist Therapeutics price target raised to $121 from $110 at Truist

Truist analyst Srikripa Devarakonda raised the firm’s price target on Protagonist Therapeutics (PTGX) to $121 from $110 and keeps a Buy rating on the shares. Following J&J’s (JNJ) commentary on…

Other symbols: JNJ
6 weeks ago - TheFly

Protagonist Therapeutics price target raised to $116 from $104 at Clear Street

Clear Street analyst Kaveri Pohlman raised the firm’s price target on Protagonist Therapeutics (PTGX) to $116 from $104 and keeps a Buy rating on the shares. Following management meetings, the…

7 weeks ago - TheFly

Protagonist Announces Presentation of One-Year Phase 3 Data for ICOTYDE(TM) in Moderate-to-Severe Plaque Psoriasis at the 2026 American Academy of Dermatology (AAD) Annual Meeting

One-year Phase 3 data for ICOTYDE to be presented at AAD 2026 demonstrate lasting skin clearance and a favorable safety profile in a once daily pill for moderate-to-severe plaque psoriasis Results fur...

2 months ago - Accesswire

Protagonist price target raised to $110 from $107 at Leerink

Leerink analyst Faisal Khurshid raised the firm’s price target on Protagonist Therapeutics (PTGX) to $110 from $107 and keeps an Outperform rating on the shares. The firm is “impressed” with…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $120 from $112 at Citizens

Citizens raised the firm’s price target on Protagonist Therapeutics (PTGX) to $120 from $112 and keeps an Outperform rating on the shares. The firm says Icotyde’s approval represents a “meaningful…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $112 from $100 at Wedbush

Wedbush raised the firm’s price target on Protagonist Therapeutics (PTGX) to $112 from $100 and keeps an Outperform rating on the shares. The firm believes the FDA approval of Icotyde…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $106 from $95 at JPMorgan

JPMorgan analyst Brian Cheng raised the firm’s price target on Protagonist Therapeutics (PTGX) to $106 from $95 and keeps an Overweight rating on the shares after the company received FDA…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $125 from $115 at Citi

Citi raised the firm’s price target on Protagonist Therapeutics (PTGX) to $125 from $115 and keeps a Buy rating on the shares. The views the FDA approval of Icotyde as…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $119 from $113 at Barclays

Barclays raised the firm’s price target on Protagonist Therapeutics (PTGX) to $119 from $113 and keeps an Overweight rating on the shares. The FDA approved Icotyde for patients with psoriasis…

2 months ago - TheFly

Protagonist Therapeutics price target raised to $104 from $91 at Clear Street

Clear Street raised the firm’s price target on Protagonist Therapeutics (PTGX) to $104 from $91 and keeps a Buy rating on the shares following the FDA approval of icotrokinra for…

2 months ago - TheFly