Alnylam Pharmaceuticals, Inc. (ALNY)

NASDAQ: ALNY · Real-Time Price · USD
400.59
-0.10 (-0.02%)
At close: Dec 26, 2025, 4:00 PM EST
400.28
-0.31 (-0.08%)
After-hours: Dec 26, 2025, 4:15 PM EST
-0.02%
Market Cap52.92B
Revenue (ttm)3.21B
Net Income (ttm)43.57M
Shares Out 132.11M
EPS (ttm)0.33
PE Ratio1,214.82
Forward PE60.47
Dividendn/a
Ex-Dividend Daten/a
Volume401,419
Open404.58
Previous Close400.69
Day's Range397.31 - 404.58
52-Week Range205.87 - 495.55
Beta0.30
AnalystsStrong Buy
Price Target479.45 (+19.69%)
Earnings DateFeb 12, 2026

About ALNY

Alnylam Pharmaceuticals, Inc. discovers, develops, and commercializes therapeutics based on ribonucleic acid interference. It offers ONPATTRO and AMVUTTRA for hereditary transthyretin-mediated amyloidosis; GIVLAARI for acute hepatic porphyria; OXLUMO for primary hyperoxaluria type 1; and Leqvio for hypercholesterolemia. It also develops vutrisiran, which is in phase III clinical trial for transthyretin amyloidosis (ATTR) with cardiomyopathy; Nucresiran that is in phase I clinical trial for ATTR amyloidosis; Fitusiran, which is in phase III clin... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 28, 2004
Employees 2,230
Stock Exchange NASDAQ
Ticker Symbol ALNY
Full Company Profile

Financial Performance

In 2024, Alnylam Pharmaceuticals's revenue was $2.25 billion, an increase of 22.97% compared to the previous year's $1.83 billion. Losses were -$278.16 million, -36.82% less than in 2023.

Financial Statements

Analyst Summary

According to 28 analysts, the average rating for ALNY stock is "Strong Buy." The 12-month stock price target is $479.45, which is an increase of 19.69% from the latest price.

Price Target
$479.45
(19.69% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

This year's biotech laggards primed for 2026 recovery, says Goldman Sachs' Richter

CNBC's “Closing Bell Overtime” team discusses why the biotech recovery may continue into 2026 with Salveen Richter, lead U.S. biotech analyst at Goldman Sachs Research.

Other symbols: AMGNARGXAZNIBB
8 days ago - CNBC Television

Alnylam to Invest $250 Million to Add Enzymatic Ligation Platform to U.S. Manufacturing Facility to Meet Growing Global Demand for RNAi Therapeutics

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced the planned expansion of its state-of-the-art manufacturing faci...

10 days ago - Business Wire

Is Alnylam Entering A Corrective Phase After A Strong Run?

Alnylam (NASDAQ: ALNY) has corrected by roughly 13% over the past couple of weeks. To understand why this pullback is unfolding now, it is important to examine the stock's structure through the lens o...

12 days ago - Benzinga

Walmart was too late for a Nasdaq-100 spot — but these 6 stocks made the cut

Six companies will join the Nasdaq-100 later this month — but not Walmart, which switched its listing away from the New York Stock Exchange too late to qualify for a spot in the tech-heavy index.

Other symbols: WMTFERMPWRSTXWDC
14 days ago - Market Watch

Eight stock picks to play one of the healthiest corners of the market

The healthcare sector of the U.S. stock market as a whole is cheaply priced, which can make it attractive to investors concerned that the S&P 500 has gotten too expensive several years into a bull mar...

16 days ago - Market Watch

Alnylam Announces Partial Repurchase of 1.00% Convertible Senior Notes Due 2027

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (“Alnylam”) (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it has entered into separate, privately negotia...

17 days ago - Business Wire

Alnylam Pharmaceuticals Announces Changes to Board of Directors

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced changes to its Board of Directors, including the departure of tw...

24 days ago - Business Wire

CRH, Vertiv, Ares, Alnylam Could Be Added to S&P 500 Friday in Rebalancing

Those four companies, culled from a list drawn up by KBW analyst Shreyank Gandhi, are among the largest not in the index.

Other symbols: CRHVRTARCC
26 days ago - Barrons

American Century Ultra Fund Q3 2025 Contributors/Detractors And Notable Trades

Google's parent company received a relatively benign antitrust ruling that would not force Alphabet to sell its Chrome browser or Android operating system. Chipotle Mexican Grill reported mixed quarte...

27 days ago - Seeking Alpha

What's Going On With Alnylam Stock On Friday?

Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) stock is trading higher on Friday, with no news to justify the movement.

4 weeks ago - Benzinga

Virtus Silvant Mid-Cap Growth Fund Q3 2025 Performance Review

The Virtus Silvant Mid-Cap Growth Fund returned +5.43% (Class INST) for the quarter, compared to the Russell Midcap Growth Index's return of +2.78%. Palantir Technologies (PLTR) and Roblox (RBLX) were...

4 weeks ago - Seeking Alpha

UK's drug-cost watchdog recommends Alnylam's heart disease drug

The UK's drug cost-effectiveness watchdog has recommended Alnylam Pharmaceuticals' heart disease drug, ensuring access for patients through the government health system in England and Wales, the compa...

5 weeks ago - Reuters

Alnylam Pharmaceuticals, Inc. (ALNY) Presents at Jefferies London Healthcare Conference 2025 Transcript

Alnylam Pharmaceuticals, Inc. ( ALNY) Jefferies London Healthcare Conference 2025 November 19, 2025 6:30 AM EST Company Participants Yvonne Greenstreet - CEO & Director Tolga Tanguler - Executive VP ...

5 weeks ago - Seeking Alpha

Alnylam Pharmaceuticals, Inc. (ALNY) Presents at UBS Global Healthcare Conference 2025 Transcript

Alnylam Pharmaceuticals, Inc. ( ALNY) UBS Global Healthcare Conference 2025 November 10, 2025 10:15 AM EST Company Participants Jeffrey Poulton - CFO & Executive VP John Vest - Senior Vice President ...

6 weeks ago - Seeking Alpha

New Post Hoc Analysis from the HELIOS-B Phase 3 Study Shows Vutrisiran Improved Measures of Heart Structure and Function in Patients with ATTR-CM

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced results from new post hoc analyses of the HELIOS-B Phase 3 study...

7 weeks ago - Business Wire

American Century Focused Dynamic Growth Fund Q3 2025 Performance Contributors And Detractors

Google's parent company received a relatively benign antitrust ruling that would not force Alphabet to sell its Chrome browser or Android operating system. Alnylam's shares benefited from a positive p...

7 weeks ago - Seeking Alpha

Alnylam to Webcast Presentations at Upcoming November Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present company overviews at the following ...

7 weeks ago - Business Wire

Biotech is back. Here's why these rallying stocks belong in your portfolio now.

The volatile sector is seeing greater stability, and these four stocks can profit.

7 weeks ago - Market Watch

Alnylam Pharmaceuticals: Q3 Earnings Review - A Sensational Year Reaches Its Peak

Alnylam Pharmaceuticals, Inc. delivered strong Q3 results, driven by Amvuttra's success in ATTR-CM, with total revenues soaring to $1.25 billion. ALNY's market cap surged to $59B as Amvuttra outperfor...

2 months ago - Seeking Alpha

Alnylam Pharmaceuticals, Inc. (ALNY) Q3 2025 Earnings Call Transcript

Alnylam Pharmaceuticals, Inc. ( ALNY) Q3 2025 Earnings Call October 30, 2025 8:30 AM EDT Company Participants Christine Lindenboom - Chief Corporate Communications Officer Yvonne Greenstreet - CEO & ...

2 months ago - Seeking Alpha

Why Is Alnylam Pharmaceuticals Stock Trading Lower Thursday?

Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) stock is trading lower after the company reported third-quarter earnings.

2 months ago - Benzinga

Alnylam Pharmaceuticals Reports Third Quarter 2025 Financial Results and Highlights Recent Period Progress

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today reported its consolidated financial results for the third quarter ended Se...

2 months ago - Business Wire

Alnylam to Webcast Conference Call Discussing Third Quarter 2025 Financial Results

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it will report financial results for the third quarter endi...

2 months ago - Business Wire

Alnylam Announces First Patient Dosed in ZENITH Global Phase 3 Cardiovascular Outcomes Trial of Zilebesiran

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced that the first patient has been dosed in ZENITH (ZilebEsiraN Car...

3 months ago - Business Wire

New Data from HELIOS-B Phase 3 Study Demonstrate Lower Rates of Gastrointestinal Events in ATTR-CM Patients Treated with Vutrisiran

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced results from new analyses of the HELIOS-B Phase 3 study of AMVUT...

3 months ago - Business Wire