Aprea Therapeutics, Inc. (APRE)

NASDAQ: APRE · Real-Time Price · USD
0.9100
-0.0400 (-4.21%)
At close: May 26, 2026, 4:00 PM EDT
0.8901
-0.0199 (-2.19%)
After-hours: May 26, 2026, 6:36 PM EDT
Market Cap10.90M +19.3%
Revenue (ttm)123,296 -90.4%
Net Income-11.95M
EPS-1.37
Shares Out 11.98M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume112,708
Open0.9600
Previous Close0.9500
Day's Range0.9000 - 0.9700
52-Week Range0.5480 - 2.2200
Beta1.52
AnalystsStrong Buy
Price Target4.30 (+372.53%)
Earnings DateMay 13, 2026

About APRE

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Oct 3, 2019
Employees 8
Stock Exchange NASDAQ
Ticker Symbol APRE
Full Company Profile

Financial Performance

In 2025, Aprea Therapeutics's revenue was $285,759, a decrease of -80.98% compared to the previous year's $1.50 million. Losses were -$12.60 million, -2.77% less than in 2024.

Financial Statements

Analyst Summary

According to 4 analysts, the average rating for APRE stock is "Strong Buy." The 12-month stock price target is $4.3, which is an increase of 372.53% from the latest price.

Price Target
$4.3
(372.53% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Aprea Therapeutics price target lowered to $6 from $7 at Wedbush

Wedbush analyst Robert Driscoll lowered the firm’s price target on Aprea Therapeutics (APRE) to $6 from $7 and keeps an Outperform rating on the shares. The firm notes the company…

12 days ago - TheFly

Aprea Therapeutics reports Q1 EPS (22c) vs. (66c) last year

As of March 31 the Company reported cash and cash equivalents of $46.5M compared to $14.6M as of December 31, 2025. The Company believes that its cash will be sufficient…

13 days ago - TheFly

Aprea Therapeutics Earnings release: Q1 2026

Aprea Therapeutics released its Q1 2026 earnings on May 13, 2026, summarizing the period's financial results.

13 days ago - Filings

Aprea Therapeutics Quarterly report: Q1 2026

Aprea Therapeutics has published its Q1 2026 quarterly earnings report on May 13, 2026.

13 days ago - Filings

Aprea Therapeutics Reports First Quarter 2026 Financial Results and Provides a Corporate Update

DOYLESTOWN, Pa., May 13, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and...

13 days ago - GlobeNewsWire

Aprea Therapeutics initiated with an Outperform at Oppenheimer

Oppenheimer initiated coverage of Aprea Therapeutics (APRE) with an Outperform rating and $5 price target The firm cites the potential of the company’s WEE1 inhibitor APR-1051 and the stock’s “sizable...

19 days ago - TheFly

Aprea Therapeutics Proxy statement: Proxy filing

Aprea Therapeutics filed a proxy statement on April 30, 2026, providing details for shareholder voting and corporate governance matters.

26 days ago - Filings

Aprea Therapeutics Proxy statement: Proxy filing

Aprea Therapeutics filed a proxy statement on April 30, 2026, providing details for shareholder voting and corporate governance matters.

26 days ago - Filings

Aprea Therapeutics files to sell 74.35M shares of common stock for holders

17:02 EDT Aprea Therapeutics (APRE) files to sell 74.35M shares of common stock for holders

4 weeks ago - TheFly

Aprea Therapeutics Registration statement: Registration filing

Aprea Therapeutics filed a registration statement on April 22, 2026, providing details about a securities offering with the SEC.

4 weeks ago - Filings

Aprea Therapeutics to Provide Clinical Update on ACESOT-1051 Phase 1 Trial Evaluating WEE1 Inhibitor, APR-1051, at ASCO 2026 Annual Meeting

DOYLESTOWN, Pa., April 21, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery a...

5 weeks ago - GlobeNewsWire

Aprea Therapeutics Proxy statement: Proxy filing

Aprea Therapeutics filed a proxy statement on April 20, 2026, providing details for shareholder voting and corporate governance matters.

5 weeks ago - Filings

Aprea Therapeutics Announces Closing of Oversubscribed $30 Million Private Placement

DOYLESTOWN, Pa., April 01, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery a...

7 weeks ago - GlobeNewsWire

Aprea Therapeutics price target lowered to $1.20 from $4 at H.C. Wainwright

H.C. Wainwright lowered the firm’s price target on Aprea Therapeutics (APRE) to $1.20 from $4 and keeps a Buy rating on the shares. The firm cites the “significant dilution” from…

2 months ago - TheFly

Aprea Therapeutics confirms partial response in ongoing ACESOT-1051 trial

Aprea Therapeutics (APRE) announced the confirmation of a partial response, or PR, in its ongoing ACESOT-1051 trial evaluating APR-1051, a potent and selective WEE1 kinase inhibitor. The confirmed PR ...

2 months ago - TheFly

Aprea Therapeutics Announces Oversubscribed $30 Million Private Placement

Financing led by Soleus Capital with participation from Vestal Point Capital, Squadron Capital Management and additional new and existing investors DOYLESTOWN, Pa., March 30, 2026 (GLOBE NEWSWIRE) -- ...

2 months ago - GlobeNewsWire

Aprea Therapeutics Highlights Positive Emerging Clinical Activity for WEE1 Inhibitor, APR-1051, with a Confirmed Partial Response in the Ongoing Phase 1 ACESOT-1051 Trial

Confirmed partial response at 220 mg indicates anti-tumor activity of APR-1051 in biomarker-defined cancers Early clinical data suggest the potential of APR-1051 as a best-in-class WEE1 inhibitor Emer...

2 months ago - GlobeNewsWire

Aprea Therapeutics Registration statement: Registration Filing

Aprea Therapeutics filed a registration statement on March 17, 2026, providing details about a securities offering with the SEC.

2 months ago - Filings

Aprea Therapeutics reports Q4 EPS (32c) vs. (49c) last year

Reports revenue $3,337 vs. $205,817 last year. “We enter 2026 with strong momentum following a year of meaningful execution across our portfolio,” said Oren Gilad, Ph.D., President and Chief Executive...

2 months ago - TheFly

Aprea Therapeutics sees cash runway into 1Q27

As of December 31, 2025, Aprea reported cash and cash equivalents of $14.6 million compared to $22.8 million as of December 31, 2024. The Company believes its cash and cash…

2 months ago - TheFly

Aprea Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides a Corporate Update

DOYLESTOWN, Pa., March 16, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery a...

2 months ago - GlobeNewsWire

Aprea Therapeutics Annual report: Q4 2025

Aprea Therapeutics has published its Q4 2025 annual report on March 16, 2026.

2 months ago - Filings

Aprea Therapeutics Earnings release: Q4 2025

Aprea Therapeutics released its Q4 2025 earnings on March 16, 2026, summarizing the period's financial results.

2 months ago - Filings

Aprea Therapeutics Slides: Corporate presentation

Aprea Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on March 16, 2026.

2 months ago - Filings

Aprea Therapeutics Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

The presentation highlighted promising early clinical results for a next-generation WEE1 inhibitor, showing strong efficacy and safety in biomarker-selected patients. Dose escalation is ongoing, with plans to expand cohorts and explore combination therapies, supported by a solid financial position.

3 months ago - Transcripts