Bolt Biotherapeutics Earnings Call Transcripts
Fiscal Year 2025
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BDC-3042 demonstrated strong safety and early efficacy in phase I, especially in refractory NSCLC, with a confirmed partial response and ongoing stable disease. BDC-4182's trial is open, targeting a broader Claudin 18.2 market, and partnering discussions for BDC-3042 are progressing.
Fiscal Year 2024
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The presentation highlighted a robust pipeline with two proprietary immunotherapy programs, strong financials supporting operations through mid-2026, and fully funded collaborations. Next-generation ISACs show enhanced efficacy and safety, with key clinical milestones expected in 2025.
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The ISAC platform shows promise for durable tumor responses, with next-gen programs targeting broader tumor types and lower antigen expression. Key clinical data from BDC-3042 and BDC-4182 are expected in the next year, supported by strong partnerships and a cash runway to mid-2026.