Denali Therapeutics Inc. (DNLI)

NASDAQ: DNLI · Real-Time Price · USD

18.18

-0.48 (-2.57%)

Oct 23, 2026, 9:43 AM EDT - Market open

Denali Therapeutics Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Total Valuation

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 23, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Capitalization	2,906	2,578	2,933	2,966	3,777	5,447
Market Cap Growth	15.22%	-12.10%	-1.10%	-21.48%	-30.66%	-45.77%
Enterprise Value	2,004	1,750	1,704	1,902	2,733	4,153
Last Close Price	18.66	16.51	20.38	21.46	27.81	44.60

Price Ratios

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 23, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Forward PE	-	46.46	46.46	46.46	46.46	46.46
PS Ratio	827.62	-	-	8.97	34.82	111.93
PB Ratio	3.57	2.54	2.38	2.88	3.62	5.66
P/TBV Ratio	3.73	2.54	2.38	2.88	3.62	5.66

EV Ratios

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 23, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
EV/Sales Ratio	577.26	-	-	5.76	25.20	85.35

Financial Efficiency

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 23, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Debt / Equity Ratio	0.05	0.04	0.04	0.05	0.06	0.07
Net Debt / Equity Ratio	-1.08	-0.91	-0.92	-0.95	-1.22	-1.27
Net Debt / EBITDA Ratio	1.72	1.71	2.31	5.23	3.86	4.27
Net Debt / FCF Ratio	2.06	2.19	3.13	2.65	4.86	5.58
Asset Turnover	0.00	-	-	0.25	0.08	0.03
Quick Ratio	7.95	8.85	8.16	13.31	3.70	2.29
Current Ratio	8.37	9.16	8.46	13.65	3.77	2.37
Return on Equity (ROE)	-54.93%	-45.69%	-37.40%	-14.01%	-32.52%	-27.51%
Return on Assets (ROA)	-29.15%	-27.56%	-24.82%	-9.40%	-14.87%	-12.29%
Return on Invested Capital (ROIC)	-769.52%	-173.59%	-200.61%	-	-	-
Return on Capital Employed (ROCE)	-50.80%	-53.10%	-39.50%	-18.30%	-31.10%	-28.80%

Yields

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Oct '26 Oct 23, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Earnings Yield	-15.59%	-19.88%	-14.41%	-4.90%	-8.63%	-5.33%
FCF Yield	-14.67%	-16.37%	-12.40%	-12.51%	-6.95%	-4.04%
Buyback Yield / Dilution	-5.80%	-4.97%	-19.73%	-9.43%	-3.30%	-7.83%

SEC Filings: 10-K · 10-Q