Lexicon Pharmaceuticals, Inc. (LXRX)

NASDAQ: LXRX · Real-Time Price · USD
1.430
+0.050 (3.62%)
At close: Nov 6, 2025, 4:00 PM EST
1.370
-0.060 (-4.20%)
After-hours: Nov 6, 2025, 7:52 PM EST
3.62%
Market Cap519.66M
Revenue (ttm)70.86M
Net Income (ttm)-68.58M
Shares Out 363.40M
EPS (ttm)-0.20
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume2,937,307
Open1.400
Previous Close1.380
Day's Range1.390 - 1.525
52-Week Range0.284 - 1.660
Beta0.97
AnalystsBuy
Price Target3.23 (+125.87%)
Earnings DateNov 6, 2025

About LXRX

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company offers Sotagliflozin, an orally-delivered small molecule drug to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease or CKD, and other cardiovascular risk factors. Its orally-delivered small molecule drug candidates u... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 7, 2000
Employees 103
Stock Exchange NASDAQ
Ticker Symbol LXRX
Full Company Profile

Financial Performance

In 2024, Lexicon Pharmaceuticals's revenue was $31.08 million, an increase of 2481.48% compared to the previous year's $1.20 million. Losses were -$200.40 million, 13.1% more than in 2023.

Financial Statements

Analyst Summary

According to 5 analysts, the average rating for LXRX stock is "Buy." The 12-month stock price target is $3.23, which is an increase of 125.87% from the latest price.

Price Target
$3.23
(125.87% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Lexicon Pharmaceuticals, Inc. (LXRX) Q3 2025 Earnings Call Transcript

Lexicon Pharmaceuticals, Inc. ( LXRX) Q3 2025 Earnings Call November 6, 2025 8:30 AM EST Company Participants Lisa DeFrancesco - Senior Vice President of Investor Relations & Corporate Communications...

8 hours ago - Seeking Alpha

Lexicon Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides R&D Updates

FDA End-of-Phase 2 meeting for pilavapadin in DPNP to be held by year-end All IND-enabling studies of LX9851 for obesity completed and submitted to licensee Novo Nordisk Site initiation for SONATA-HCM...

14 hours ago - GlobeNewsWire

Data Demonstrating Unique Benefits of Sotagliflozin in Diverse Patient Populations will be Presented at the Hypertrophic Cardiomyopathy Society and American Heart Association's Sessions 2025 in New Orleans

THE WOODLANDS, Texas, Nov. 04, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.   (Nasdaq: LXRX) today announced that data from three studies of sotagliflozin will be presented during upcoming m...

2 days ago - GlobeNewsWire

Lexicon Pharmaceuticals to Report Third Quarter 2025 Financial Results on November 6, 2025

THE WOODLANDS, Texas, Oct. 30, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will release its third quarter 2025 financial results on Thursday, Nove...

7 days ago - GlobeNewsWire

Lexicon Pharmaceuticals Presents Additional Pilavapadin Data in Diabetic Peripheral Neuropathic Pain at 19th Annual Pain Therapeutics Summit

– Results support advancement of 10 mg dose into Phase 3 development – – End-of-Phase 2 meeting request accepted by U.S. FDA; partnership discussions progressing – THE WOODLANDS, Texas, Oct. 14, 2025 ...

23 days ago - GlobeNewsWire

Lexicon Pharmaceuticals Convenes Roundtable to Address Public Policy Gaps for People with Chronic Pain

Diverse group of stakeholders aligned around the importance of elevating public awareness of need for new treatments for chronic pain and the need to expand the Alternatives to PAIN Act Diverse group ...

4 weeks ago - GlobeNewsWire

Lexicon Pharmaceuticals Announces Update on Submission of Additional Data to U.S. FDA Supporting the Benefit-Risk Profile of Zynquista® in Type 1 Diabetes

Data obtained from ongoing third-party funded, investigator-sponsored trials have been submitted in effort to address the December 2024 complete response letter

6 weeks ago - GlobeNewsWire

Pilavapadin Provides Meaningful Pain Reduction in Adults with Diabetic Peripheral Neuropathic Pain (DPNP) in Data Presented at the European Association for the Study of Diabetes (EASD) and NEUROdiab Annual Meetings

Pilavapadin 10 mg resulted in a two-point reduction from baseline in average daily pain scores (ADPS) by week 11 and was well tolerated in PROGRESS Phase 2b study Pilavapadin 10 mg resulted in a two-p...

7 weeks ago - GlobeNewsWire

Lexicon Pharmaceuticals to Present Additional Clinical Data on Pilavapadin at Three Upcoming Medical Meetings

Presentations collectively highlight pilavapadin's potential to improve pain management care for patients with diabetic peripheral neuropathic pain (DPNP)

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals Announces Submission of Additional Data to U.S. FDA Supporting the Benefit-Risk Profile of Zynquista® in Type 1 Diabetes

Data obtained from ongoing third-party funded, investigator-sponsored trials have been submitted in effort to address the December 2024 complete response letter

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Present New Preclinical Data on Pilavapadin in Chemotherapy-Induced Pain and Multiple Sclerosis Pain at NeuPSIG 2025

THE WOODLANDS, Texas, Sept. 04, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) today announced that the Company will present new data demonstrating the reduction of neuropathic...

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals, Inc. (LXRX) Presents At Citi's Biopharma Back To School Conference Transcript

Lexicon Pharmaceuticals, Inc. (NASDAQ:LXRX) Citi's Biopharma Back to School Conference September 3, 2025 1:45 PM EDT Company Participants Michael Exton - CEO & Director Craig Granowitz - Senior VP & ...

2 months ago - Seeking Alpha

Lexicon Pharmaceuticals Announces Presentation of Diabetic Peripheral Neuropathic Pain Patient Insights at PAINWeek 2025

THE WOODLANDS, Texas, Sept. 03, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) today announced data from a study of patients describing the physical and psychological impact of...

2 months ago - GlobeNewsWire

Sotagliflozin Provides Consistent Relative Risk Reduction in Heart Failure and Major Cardiovascular Events Across All Age Ranges, Including Greater Than 75, in Data Presented at the European Society of Cardiology (ESC) 2025 Congress

THE WOODLANDS, Texas, Sept. 02, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) announced that a post-hoc analysis (“Efficacy of Sotagliflozin Among Older Adults: A Pooled Analys...

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Participate at Two Upcoming Investor Conferences

THE WOODLANDS, Texas, Aug. 27, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at Citi's Biopharma Bac...

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals, Inc. (LXRX) Q2 2025 Earnings Call Transcript

Lexicon Pharmaceuticals, Inc. (NASDAQ:LXRX) Q2 2025 Earnings Conference Call August 6, 2025 8:30 AM ET Company Participants Craig B. Granowitz - Senior VP & Chief Medical Officer Lisa M.

3 months ago - Seeking Alpha

Lexicon Pharmaceuticals Reports Second Quarter 2025 Financial Results and Provides Business Updates

Partnership discussions for pilavapadin remain underway following Phase 2b PROGRESS study results IND-enabling studies of LX9851 for obesity and related disorders on track for completion in 2025 with ...

3 months ago - GlobeNewsWire

Lexicon Pharmaceuticals Regains Compliance with Nasdaq Minimum Bid Price Requirement

THE WOODLANDS, Texas, July 31, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Nasdaq's listing qualifications staff has determined that the closing bid pric...

3 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Report Second Quarter 2025 Financial Results on August 6, 2025

THE WOODLANDS, Texas, July 23, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will release its second quarter 2025 financial results on Wednesday, Au...

3 months ago - GlobeNewsWire

Lexicon to Present Patient-reported Data on Diabetic Peripheral Neuropathic Pain (DPNP) at the 7th Annual Meeting of the American Society of Pain and Neuroscience (ASPN 2025)

Patient insights informed the development of pilavapadin, Lexicon's investigational, novel, non-opioid treatment for people suffering from DPNP Patient insights informed the development of pilavapadin...

3 months ago - GlobeNewsWire

Data Demonstrating Sotagliflozin Reduces the Risk of Clinically Important Hypoglycemic Events in Adults with Type 1 Diabetes When Added to Insulin Presented at the 85th Scientific Sessions of the American Diabetes Association (ADA)

Oral presentation highlighted the post-hoc analysis during the “Interventions to Prevent Hypoglycemia: Bench to Bedside” session Treatment with sotagliflozin resulted in no increased risk and a reduct...

4 months ago - GlobeNewsWire

Lexicon to Present Data at the 85th Scientific Sessions of the American Diabetes Association (ADA)

THE WOODLANDS, Texas, June 18, 2025 (GLOBE NEWSWIRE) --   Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) today announced that data from a study evaluating the impact of sotagliflozin on hypoglycemia in...

5 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Present at the 2025 Jefferies Global Healthcare Conference

THE WOODLANDS, Texas, May 29, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 2025 Jefferies Gl...

5 months ago - GlobeNewsWire

SONATA-HCM Study Design Presented at Heart Failure 2025, the Annual Congress of the Heart Failure Association of the European Society of Cardiology

Lexicon is evaluating the safety and efficacy of sotagliflozin in patients with both obstructive and  non-obstructive hypertrophic cardiomyopathy (HCM) Pivotal Phase 3 clinical trial is actively enrol...

6 months ago - GlobeNewsWire

Lexicon Pharmaceuticals, Inc. (LXRX) Q1 2025 Earnings Call Transcript

Lexicon Pharmaceuticals, Inc. (NASDAQ:LXRX) Q1 2025 Earnings Conference Call May 13, 2025 5:00 PM ET Company Participants Lisa DeFrancesco - Senior Vice President, Investor Relations and Corporate St...

6 months ago - Seeking Alpha