Lexicon Pharmaceuticals, Inc. (LXRX)

NASDAQ: LXRX · Real-Time Price · USD
2.000
+0.320 (19.05%)
At close: May 8, 2026, 4:00 PM EDT
1.942
-0.058 (-2.93%)
After-hours: May 8, 2026, 7:54 PM EDT
Market Cap847.36M +233.5%
Revenue (ttm)69.64M +123.1%
Net Income-26.09M
EPS-0.07
Shares Out 423.68M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume7,018,734
Open1.690
Previous Close1.680
Day's Range1.640 - 2.000
52-Week Range0.514 - 2.000
Beta0.97
AnalystsStrong Buy
Price Target4.15 (+107.5%)
Earnings DateMay 7, 2026

About LXRX

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart fail... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 7, 2000
Employees 81
Stock Exchange NASDAQ
Ticker Symbol LXRX
Full Company Profile

Financial Performance

In 2025, Lexicon Pharmaceuticals's revenue was $49.80 million, an increase of 60.24% compared to the previous year's $31.08 million. Losses were -$50.34 million, -74.88% less than in 2024.

Financial Statements

Analyst Summary

According to 2 analysts, the average rating for LXRX stock is "Strong Buy." The 12-month stock price target is $4.15, which is an increase of 107.50% from the latest price.

Price Target
$4.15
(107.50% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Lexicon Pharmaceuticals Earnings Call Transcript: Q1 2026

Q1 2026 saw a sharp revenue increase from milestone payments and reduced net loss, with strong cash reserves and lower expenses. Key pipeline programs advanced toward major regulatory milestones, and financial flexibility was enhanced through a new debt facility.

3 days ago - Transcripts

Lexicon Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Clinical Updates

SONATA-HCM anticipated to be fully enrolled mid-2026  Resubmission of NDA for ZYNQUISTA ® in type 1 diabetes anticipated mid-2026 with potential for approval this year Clinical development of LX9851 i...

3 days ago - GlobeNewsWire

Lexicon Pharmaceuticals Announces $100 Million Loan Facility with Hercules Capital

THE WOODLANDS, Texas, May 04, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) announced today that it has entered into a loan facility with Hercules Capital, Inc. (NYSE: HTGC) th...

Other symbols: HTGC
6 days ago - GlobeNewsWire

Lexicon Pharmaceuticals to Report First Quarter 2026 Financial Results on May 7, 2026

THE WOODLANDS, Texas, April 30, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will release its first quarter 2026 financial results on Thursday, May...

10 days ago - GlobeNewsWire

Lexicon to present data at AAN annual meeting on Progress Phase 2b study

Lexicon (LXRX) Pharmaceuticals announced that results from its Progress Phase 2b study of pilavapadin in diabetic peripheral neuropathic pain, DPNP, supporting the selection of pilavapadin 10 mg as th...

23 days ago - TheFly

Lexicon to Present Data at the American Academy of Neurology (AAN) Annual Meeting

Oral presentation highlights additional data from PROGRESS Phase 2b study of pilavapadin supporting selection of 10mg as optimal dose for Phase 3 development in DPNP

23 days ago - GlobeNewsWire

Lexicon Announces Three Presentations at the American College of Cardiology (ACC) Annual Scientific Session & Expo

Additional analyses from the SCORED and SOTA-P-CARDIA studies provide further evidence of benefits across patient subgroups potentially related to sotagliflozin's mechanism of action Additional analys...

6 weeks ago - GlobeNewsWire

Lexicon, Novo Nordisk announce initiation of LX9851 study

Lexicon (LXRX) and Novo Nordisk (NVO) announced that Novo Nordisk has initiated a Phase 1 study with LX9851, an oral non-incretin development candidate. In March 2025, Lexicon signed an exclusive

Other symbols: NVO
6 weeks ago - TheFly

Lexicon Pharmaceuticals and Novo Nordisk Announce initiation of Phase 1 study with oral obesity drug candidate LX9851

LX9851 is a first-in-class, oral non-incretin candidate being developed by Novo Nordisk for the treatment of obesity and associated metabolic disorders

6 weeks ago - GlobeNewsWire

Lexicon Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

The company is advancing late-stage programs in HCM, type 1 diabetes, and neuropathic pain, with strong regulatory engagement and strategic partnerships. Key milestones include imminent Phase 3 data, NDA resubmission, and new obesity drug trials with Novo Nordisk.

2 months ago - Transcripts

Lexicon announces results from post hoc analysis on data of sotagliflozin

Lexicon (LXRX) Pharmaceuticals announced that results of a post hoc analysis of clinical data evaluating the impact of kidney function on the long-term efficacy and safety of sotagliflozin on people

2 months ago - TheFly

Lexicon to Present Data on Effect of Kidney Function on the Long-term Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes at 19th International Conference on Advanced Technologies & Treatments for Diabetes

THE WOODLANDS, Texas, March 11, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) today announced that results of a post hoc analysis of clinical data evaluating the impact of kid...

2 months ago - GlobeNewsWire

Lexicon price target raised to $2.30 from $2.10 at Citi

Citi analyst Yigal Nochomovitz raised the firm’s price target on Lexicon (LXRX) to $2.30 from $2.10 and keeps a Buy rating on the shares.

2 months ago - TheFly

Lexicon price target raised to $6 from $4 at H.C. Wainwright

H.C. Wainwright raised the firm’s price target on Lexicon (LXRX) to $6 from $4 and keeps a Buy rating on the shares following the Q4 report. The firm increased its

2 months ago - TheFly

Lexicon Pharmaceuticals Earnings Call Transcript: Q4 2025

Advanced late-stage programs in cardiometabolic and chronic pain, reduced operating expenses by $129.5M year-over-year, and strengthened cash position by over $100M. Key milestones include over 50% enrollment in SONATA-HCM, NDA resubmission for Zynquista in 2026, and pilavapadin Phase III readiness.

2 months ago - Transcripts

Lexicon reports Q4 EPS (4c), consensus (7c)

Reports Q4 revenue $5.5M, consensus $3.14M. As of December 31, 2025, Lexicon (LXRX) had $125.2M in cash, investments and restricted cash, as compared to $238.0M in cash and investments as

2 months ago - TheFly

Lexicon Pharmaceuticals Reports Fourth Quarter 2025 Financial Results and Provides Clinical Updates

Pivotal sotagliflozin milestones on schedule including resubmission of NDA in T1D and enrollment of SONATA study for HCM  Positive End-of-Phase 2 meeting with FDA for pilavapadin confirms Phase 3 read...

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Participate in Three Upcoming March Investor Conferences

THE WOODLANDS, Texas, March 03, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Company management will participate in an upcoming fireside chat at the 2026 ...

2 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Report Fourth Quarter 2025 Financial Results on March 5, 2026

THE WOODLANDS, Texas, Feb. 26, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will release its fourth quarter 2025 financial results on Thursday, Mar...

2 months ago - GlobeNewsWire

Lexicon Announces Closing of Approximately $94.6 Million Public Offering and Concurrent Private Placement

THE WOODLANDS, Texas, Feb. 06, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“ Lexicon ”) today announced the closing of its previously announced underwritten public offering ...

3 months ago - GlobeNewsWire

Lexicon Announces Pricing of Approximately $94.6 Million Public Offering and Concurrent Private Placement

THE WOODLANDS, Texas, Jan. 30, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“ Lexicon ”) today announced the pricing of its previously announced underwritten public offering ...

3 months ago - GlobeNewsWire

Lexicon announces common stock offering, no amount given

Lexicon (LXRX) Pharmaceuticals announced that it has commenced an underwritten public offering to offer and sell, subject to market and other conditions, shares of its common stock. Lexicon currently ...

3 months ago - TheFly

Lexicon Announces Proposed Public Offering of Common Stock

THE WOODLANDS, Texas, Jan. 29, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“ Lexicon ”) today announced that it has commenced an underwritten public offering to offer and se...

3 months ago - GlobeNewsWire

Lexicon Pharmaceuticals to Ring the Nasdaq Closing Bell on January 27, 2026 to Celebrate 30th Anniversary

THE WOODLANDS, Texas, Jan. 23, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will ring the Nasdaq Stock Market Closing Bell on Tuesday, January 27, ...

3 months ago - GlobeNewsWire

Lexicon completes End-of-Phase 2 meeting with U.S. FDA for pilavapadin

Lexicon (LXRX) Pharmaceuticals announced the successful completion of the End-of-Phase 2, EOP2, Meeting with the U.S. Food and Drug Administration, FDA, for pilavapadin in diabetic peripheral neuropat...

3 months ago - TheFly