Oruka Therapeutics, Inc. (ORKA)

NASDAQ: ORKA · Real-Time Price · USD
69.03
+1.29 (1.90%)
At close: Apr 24, 2026, 4:00 PM EDT
69.00
-0.03 (-0.04%)
After-hours: Apr 24, 2026, 7:43 PM EDT
Market Cap3.47B +1,190.8%
Revenue (ttm)n/a
Net Income-84.31M
EPS-1.85
Shares Out 50.20M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume1,091,939
Open67.84
Previous Close67.74
Day's Range66.51 - 69.17
52-Week Range8.91 - 71.00
Betan/a
AnalystsStrong Buy
Price Target73.33 (+6.23%)
Earnings DateMay 13, 2026

About ORKA

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2004
Employees 68
Stock Exchange NASDAQ
Ticker Symbol ORKA
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 12 analysts, the average rating for ORKA stock is "Strong Buy." The 12-month stock price target is $73.33, which is an increase of 6.23% from the latest price.

Price Target
$73.33
(6.23% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Oruka Therapeutics to Host Conference Call to Report Week 16 Data for ORKA-001 from the Ongoing EVERLAST-A Trial on April 27, 2026

MENLO PARK, Calif., April 26, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standa...

5 hours ago - GlobeNewsWire

Oruka Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

ORKA-001 EVERLAST-A 16-week data now expected in 2Q 2026 following rapid enrollment, with longer-term follow-up data expected in 2H 2026

6 weeks ago - GlobeNewsWire

Oruka Therapeutics Transcript: Leerink Global Healthcare Conference 2026

Ultra-long acting antibodies targeting IL-23p19 and IL-17AF aim to transform psoriatic disease care with annual or semi-annual dosing, high efficacy, and potential off-treatment remission. Key Phase II data for ORKA-001 is expected in the second half of the year.

6 weeks ago - Transcripts

Oruka Therapeutics to Participate in Multiple Upcoming Conferences

MENLO PARK, Calif., Feb. 09, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standar...

2 months ago - GlobeNewsWire

Oruka Therapeutics Transcript: 44th Annual J.P. Morgan Healthcare Conference

The company is advancing two long-acting monoclonal antibodies for psoriatic disease, aiming for annual or biannual dosing and potential off-treatment remission. Key phase II data are expected in 2024–2025, with a strong financial position and innovative trial designs supporting differentiation from current standards.

3 months ago - Transcripts

Oruka Therapeutics Announces Positive Interim Phase 1 Data for ORKA-002 and Initiation of EVERLAST-B Trial of ORKA-001

ORKA-002 interim Phase 1 data demonstrates a half-life of 75-80 days supporting potential for twice-per-year dosing in psoriasis and quarterly dosing in hidradenitis suppurativa Phase 2 studies for OR...

3 months ago - GlobeNewsWire

Oruka Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference

MENLO PARK, Calif., Jan. 06, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standar...

3 months ago - GlobeNewsWire

Oruka Therapeutics Announces New Board Member and Board Transition

Appoints accomplished commercial leader Chris Martin to its Board of Directors Appoints accomplished commercial leader Chris Martin to its Board of Directors

4 months ago - GlobeNewsWire

Oruka Therapeutics Reports Third Quarter 2025 Financial Results and Provides Corporate Update

ORKA-001 Phase 1 results presented at EADV show potential for once-per-year dosing, higher efficacy and off-treatment remission

5 months ago - GlobeNewsWire

Oruka Therapeutics Transcript: Stifel 2025 Healthcare Conference

Two lead monoclonal antibody programs are advancing in psoriatic disease, targeting once or twice-yearly dosing and aiming for high efficacy and durable remission. Key phase II and I data readouts are expected through 2027, supported by a strong cash position.

5 months ago - Transcripts

Oruka Therapeutics to Present at Multiple November Investor Conferences

MENLO PARK, Calif., Oct. 29, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standar...

6 months ago - GlobeNewsWire

Oruka Therapeutics Announces $180 Million Private Placement

MENLO PARK, Calif., Sept. 17, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka” or the “Company”) (Nasdaq: ORKA), a biotechnology company developing novel biologics designed to set a new stan...

7 months ago - GlobeNewsWire

Oruka Therapeutics Announces Positive Interim Phase 1 Results for ORKA-001

Half-life of approximately 100 days increases likelihood of once-per-year dosing Pharmacokinetic profile supports the ability to achieve exposures that could lead to higher efficacy and extended off-t...

7 months ago - GlobeNewsWire

Oruka Therapeutics Reports Second Quarter 2025 Financial Results and Provides Corporate Update

First patients dosed in the EVERLAST-A Phase 2a trial of ORKA-001, with data expected in 2H 2026 ORKA-001 Phase 1 data and EVERLAST-A design to be presented at EADV in September 2025 ORKA-002 Phase 1 ...

9 months ago - GlobeNewsWire

Oruka Therapeutics Announces IND Clearance for EVERLAST-A Phase 2a Trial of ORKA-001 in Psoriasis with Phase 1 Data to be Presented at EADV in September

IND cleared for the EVERLAST-A Phase 2a trial of ORKA-001 in moderate-to-severe psoriasis, with initial data expected 2H 2026

9 months ago - GlobeNewsWire

Oruka Therapeutics Announces Promotion of Laura Sandler to Chief Operating Officer

MENLO PARK, Calif., July 01, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standar...

10 months ago - GlobeNewsWire

Oruka Therapeutics to Present at the Jefferies Global Healthcare Conference

MENLO PARK, Calif., May 21, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standard...

1 year ago - GlobeNewsWire

Oruka Therapeutics Announces First Participants Dosed in Phase 1 Trial of ORKA-002, its Novel Half-life Extended Anti-IL-17A/F Antibody

Pharmacokinetic and safety data from healthy volunteers anticipated around YE 2025 On track to initiate a Phase 2 study in 1H 2026 ORKA-002 preclinical data demonstrate the potential for dosing two to...

1 year ago - GlobeNewsWire

Oruka Therapeutics Reports First Quarter 2025 Financial Results and Provides Corporate Update

Continued operational excellence leading to acceleration of multiple timelines: ORKA-001, targeting IL-23p19, Phase 1 trial dosing complete, with data expected in 3Q 2025 ORKA-001 Phase 2a initiation ...

1 year ago - GlobeNewsWire

Oruka Therapeutics to Present at Bank of America Securities 2025 Health Care Conference

MENLO PARK, Calif., April 29, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standa...

1 year ago - GlobeNewsWire

Oruka Therapeutics Announces Preclinical Data for ORKA-002 at the 2025 American Academy of Dermatology Annual Meeting

Half-life in non-human primates (NHP) of more than 30 days, over three times longer than bimekizumab and expected to support a dose interval of two to three times per year

1 year ago - GlobeNewsWire

Oruka Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update

ORKA-001, targeting IL-23p19, Phase 1 trial ongoing, with pharmacokinetic (PK) data expected in 2H 2025 ORKA-001 Phase 2a initiation expected in 2H 2025, with efficacy readout in 2H 2026 that provides...

1 year ago - GlobeNewsWire

Oruka Therapeutics Transcript: TD Cowen 45th Annual Healthcare Conference

Oruka is advancing biologics for psoriatic disease with ultra-long dosing intervals and aims for multi-year remission, leveraging strong clinical design and a robust cash position. Sequential and combination regimens with ORKA-001 and ORKA-002 target best-in-class efficacy and safety.

1 year ago - Transcripts

Oruka Therapeutics to Present at Multiple March Investor Conferences

MENLO PARK, Calif., Feb. 19, 2025 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical stage biotechnology company developing novel biologics designed to set a new standar...

1 year ago - GlobeNewsWire

Oruka Therapeutics Announces First Participants Dosed in Phase 1 Trial of ORKA-001, its Novel Half-life Extended Anti-IL-23p19 Antibody

Pharmacokinetic and safety data from healthy volunteers anticipated in the second half of 2025 On track to initiate a proof-of-concept study in psoriasis in the second half of 2025, with initial effic...

1 year ago - GlobeNewsWire