Oruka Therapeutics, Inc. (ORKA)

NASDAQ: ORKA · Real-Time Price · USD
61.93
-1.97 (-3.08%)
At close: May 15, 2026, 4:00 PM EDT
61.74
-0.19 (-0.31%)
After-hours: May 15, 2026, 7:43 PM EDT
Market Cap3.74B +888.7%
Revenue (ttm)n/a
Net Income-94.19M
EPS-1.92
Shares Out 60.31M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume1,392,935
Open62.50
Previous Close63.90
Day's Range60.86 - 63.62
52-Week Range8.91 - 91.00
Betan/a
AnalystsStrong Buy
Price Target92.50 (+49.36%)
Earnings DateMay 13, 2026

About ORKA

Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2004
Employees 68
Stock Exchange NASDAQ
Ticker Symbol ORKA
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 12 analysts, the average rating for ORKA stock is "Strong Buy." The 12-month stock price target is $92.5, which is an increase of 49.36% from the latest price.

Price Target
$92.5
(49.36% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Oruka Therapeutics reports Q1 EPS (48c), consensus (54c)

“This was an important period for our company as we saw interim data for ORKA-001 that hit the upper end of our expectations on all aspects,” said Lawrence Klein, Chief…

3 days ago - TheFly

Oruka Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

ORKA-001 EVERLAST-A 16-week data showed 63.5% PASI 100 rate and a favorable tolerability profile, with longer-term data expected in 2H 2026

3 days ago - GlobeNewsWire

Halozyme licenses Hypercon technology to Oruka Therapeutics in psoriasis

Halozyme (HALO) and Oruka Therapeutics (ORKA) announced that Halozyme’s wholly-owned subsidiary, Halozyme Hypercon, has entered into a global exclusive collaboration and license agreement with Oruka. ...

Other symbols: HALO
9 days ago - TheFly

Halozyme and Oruka Announce Global Collaboration and License Agreement to Develop ORKA-001 with Hypercon™ Technology

Agreement provides exclusive rights for IL-23p19 in psoriatic disease and option for one additional target SAN DIEGO and MENLO PARK, Calif., May 6, 2026 /PRNewswire/ -- Halozyme Therapeutics, Inc. (Na...

Other symbols: HALO
10 days ago - PRNewsWire

Oruka Therapeutics price target raised to $120 from $109 at Leerink

Leerink raised the firm’s price target on Oruka Therapeutics (ORKA) to $120 from $109 and keeps an Outperform rating on the shares.

16 days ago - TheFly

Oruka Therapeutics price target raised to $120 from $75 at H.C. Wainwright

H.C. Wainwright raised the firm’s price target on Oruka Therapeutics (ORKA) to $120 from $75 and keeps a Buy rating on the shares. The EVERLAST-A “delivers in spades,” positioning ORKA-001…

17 days ago - TheFly

Oruka Therapeutics $700M Secondary priced at $72.50

Leerink, TD Cowen, Goldman Sachs, Stifel and Guggenheim acted as joint book running managers for the offering.

18 days ago - TheFly

Oruka Therapeutics Announces Pricing of Upsized $700 Million Underwritten Public Offering

MENLO PARK, Calif., April 28, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (Nasdaq: ORKA), a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics ...

18 days ago - GlobeNewsWire

Oruka Therapeutics price target raised to $100 from $75 at UBS

UBS raised the firm’s price target on Oruka Therapeutics (ORKA) to $100 from $75 and keeps a Buy rating on the shares. Oruka reported stronger than expected data for PASI-100,…

18 days ago - TheFly

Oruka Therapeutics announces $500M common stock, warrants offering

Oruka Therapeutics (ORKA) announced that it has commenced an underwritten public offering of $500M of shares of its common stock and, in lieu of common stock to certain investors, pre-funded…

19 days ago - TheFly

Oruka Therapeutics Announces Proposed $500 Million Underwritten Public Offering

MENLO PARK, Calif., April 27, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (Nasdaq: ORKA), a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics ...

19 days ago - GlobeNewsWire

Oruka Therapeutics price target raised to $131 from $71 at Clear Street

Clear Street raised the firm’s price target on Oruka Therapeutics (ORKA) to $131 from $71 and keeps a Buy rating on the shares. The firm says the company’s interim EVERLAST-A…

19 days ago - TheFly

Oruka Therapeutics rises 19.0%

Oruka Therapeutics (ORKA) is up 19.0%, or $13.12 to $82.15.

19 days ago - TheFly

Oruka Therapeutics price target raised to $160 from $78 at Barclays

Barclays analyst Etzer Darout raised the firm’s price target on Oruka Therapeutics (ORKA) to $160 from $78 and keeps an Overweight rating on the shares. The firm upped the price…

19 days ago - TheFly

Oruka Therapeutics price target raised to $165 from $85 at Wedbush

Wedbush raised the firm’s price target on Oruka Therapeutics (ORKA) to $165 from $85 and keeps an Outperform rating on the shares. The firm upped the price target after Oruka…

19 days ago - TheFly

Oruka Therapeutics price target raised to $200 from $125 at Guggenheim

Guggenheim raised the firm’s price target on Oruka Therapeutics (ORKA) to $200 from $125 and keeps a Buy rating on the shares. The firm believes ORKA-001 has “multibillion blockbuster potential”…

19 days ago - TheFly

Oruka Therapeutics rises 23.5%

Oruka Therapeutics (ORKA) is up 23.5%, or $16.23 to $85.26.

19 days ago - TheFly

Oruka Therapeutics price target raised to $151 from $78 at BTIG

BTIG raised the firm’s price target on Oruka Therapeutics (ORKA) to $151 from $78 and keeps a Buy rating on the shares. The firm notes that 16 weeks results from…

19 days ago - TheFly

This Is Why Oruka Therapeutics Stock (ORKA) Soared Today

Oruka Therapeutics stock soared after the company announced strong clinical trial results.

19 days ago - TipRanks

Oruka Therapeutics announces interim results from EVERLAST-A trial

Oruka Therapeutics (ORKA) announced interim results from its EVERLAST-A Phase 2a trial of ORKA-001, a novel half-life extended IL-23p19 monoclonal antibody, in moderate-to-severe plaque psoriasis. Ove...

19 days ago - TheFly

Oruka Therapeutics Transcript: Status update

Interim phase II data for ORKA-001 in moderate-to-severe psoriasis show 63.5% PASI 100 at week 16, surpassing other IL-23 inhibitors and matching top IL-17A/F agents. Safety is favorable, and PK supports annual dosing. A 28-week update and pivotal trial planning are upcoming.

19 days ago - Transcripts

Oruka Therapeutics Announces Positive Week 16 Data for ORKA-001 from the Ongoing EVERLAST-A Phase 2a Trial in Moderate-to-Severe Plaque Psoriasis

ORKA-001 achieved 63.5% (40/63) PASI 100 at Week 16 Favorable safety profile consistent with the IL-23p19 class Updated Phase 1 PK/PD data continue to support the potential for once-yearly dosing, wit...

19 days ago - GlobeNewsWire

Oruka Therapeutics to Host Conference Call to Report Week 16 Data for ORKA-001 from the Ongoing EVERLAST-A Trial on April 27, 2026

MENLO PARK, Calif., April 26, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standa...

20 days ago - GlobeNewsWire

Oruka Therapeutics price target raised to $85 from $45 at Wedbush

Wedbush raised the firm’s price target on Oruka Therapeutics (ORKA) to $85 from $45 and keeps an Outperform rating on the shares. The firm reviewed anticipated benchmarks and stock setup…

4 weeks ago - TheFly

Oruka Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

ORKA-001 EVERLAST-A 16-week data now expected in 2Q 2026 following rapid enrollment, with longer-term follow-up data expected in 2H 2026

2 months ago - GlobeNewsWire