Protalix BioTherapeutics, Inc. (PLX)

NYSEAMERICAN: PLX · Real-Time Price · USD
1.980
-0.020 (-1.00%)
May 15, 2026, 4:00 PM EDT - Market closed
Market Cap159.53M -33.4%
Revenue (ttm)76.38M +27.8%
Net Income15.33M +292.3%
EPS0.19 +323.9%
Shares Out 80.57M
PE Ratio10.25
Forward PE7.07
Dividendn/a
Ex-Dividend Daten/a
Volume1,100,822
Open2.000
Previous Close2.000
Day's Range1.950 - 2.045
52-Week Range1.320 - 3.190
Beta-0.01
AnalystsStrong Buy
Price Target12.00 (+506.06%)
Earnings DateMay 13, 2026

About PLX

Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company provides Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial for the treatment of gout; and PRX-119, a plant cell... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 15, 1998
Employees 226
Stock Exchange NYSEAMERICAN
Ticker Symbol PLX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to one analyst, the rating for PLX stock is "Strong Buy" and the 12-month stock price target is $12.0.

Price Target
$12.0
(506.06% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Protalix BioTherapeutics Earnings Call Transcript: Q1 2026

Q1 2026 saw a $25M milestone from Chiesi, driving net income to $18.2M and cash to $51M. Revenue guidance for 2026 is reaffirmed at $78–$83M, with strong momentum for Elfabrio and ongoing PRX-115 clinical progress.

2 days ago - Transcripts

Protalix BioTherapeutics Reports First Quarter 2026 Financial and Business Results

Company to host conference call and webcast today at 8:00 a.m. EDT Elfabrio commercial execution continues following European Commission approval of the 2 mg/kg every–4–weeks (E4W) dosing regimen; $25...

2 days ago - PRNewsWire

Protalix BioTherapeutics to Announce First Quarter 2026 Financial Results and Business Update on May 13, 2026

Company to host conference call and webcast at 8:00 a.m. EDT CARMIEL, Israel, May 6, 2026 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American: PLX), a biopharmaceutical company focused on th...

9 days ago - PRNewsWire

Protalix BioTherapeutics Earnings Call Transcript: Q4 2025

EU approval of Elfabrio's four-week dosing triggered a $25M milestone, boosting projected 2026 cash to $50M and supporting revenue growth over 50%. Pipeline advances in gout and renal indications, with strong commercial execution and high-margin contributions from Chiesi.

2 months ago - Transcripts

Protalix BioTherapeutics Reports Fiscal Year 2025 Financial and Business Results

Company to host conference call and webcast today at 8:00 a.m. EDT The European Commission (EC) approved the 2mg/kg every-4-weeks (E4W) dosing regimen for Elfabrio® in adults living with Fabry disease...

2 months ago - PRNewsWire

Protalix BioTherapeutics to Announce Fiscal Year 2025 Financial Results and Business Update on March 18, 2026

Company to host conference call and webcast at 8:00 a.m. EDT CARMIEL, Israel, March 11, 2026 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American: PLX), a biopharmaceutical company focused on...

2 months ago - PRNewsWire

Protalix, Chiesi Global Rare Diseases: EC approves dosing regimen for Elfabrio

Chiesi Global Rare Diseases and Protalix (PLX) BioTherapeutics announced that the European Commission has approved the 2mg/kg every-4-weeks dosing regimen for Elfabrio in adults living with Fabry dise...

2 months ago - TheFly

Chiesi Global Rare Diseases and Protalix BioTherapeutics Announce European Commission Approval of Additional Dosing Regimen of Every Four Weeks for Elfabrio® (pegunigalsidase alfa)

This press release is intended for US audiences for transparency relative to global news for the Fabry community. This dosing regimen for Elfabrio is not approved in the US. In the US, the FDA-approve...

2 months ago - GlobeNewsWire

Protalix, Chiesi Global: CHMP issues positive opinion for Elfabrio dosing

Chiesi Global Rare Diseases and Protalix (PLX) BioTherapeutics announced an update on Elfabrio. The Committee for Medicinal Products for Human Use of the European Medicines Agency has issued a positiv...

3 months ago - TheFly

Chiesi Global Rare Diseases and Protalix BioTherapeutics Receive Positive CHMP Opinion for an Additional Dosing Regimen of Every Four Weeks for Elfabrio® (pegunigalsidase alfa) in the EU

Committee for Medicinal Products for Human Use (CHMP) issues a positive opinion following re-examination, which will be reviewed by the European Commission (EC), with a decision anticipated by March 2...

3 months ago - GlobeNewsWire

Chiesi Global Rare Diseases and Protalix BioTherapeutics Receive Positive CHMP Opinion for an Additional Dosing Regimen of 2mg/kg Body Weight Every-Four-Weeks for Elfabrio® (pegunigalsidase alfa) ▼ in the EU

Committee for Medicinal Products for Human Use (CHMP) issues a positive opinion following re-examination, which will be reviewed by the European Commission (EC), with a decision anticipated by March 2...

3 months ago - GlobeNewsWire

Protalix BioTherapeutics Letter to Stockholders

CARMIEL, Israel, Jan. 5, 2026 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American: PLX), a biopharmaceutical company focused on the discovery, development, production and commercialization o...

4 months ago - PRNewsWire

Protalix, Secarna Pharmaceuticals enter collaboration and option agreement

Protalix (PLX) and Secarna Pharmaceuticals announced that they have entered into a collaboration and option agreement. Under this agreement, the companies have agreed to partner in the discovery of no...

5 months ago - TheFly

Protalix Biotherapeutics and Secarna Pharmaceuticals Enter into Collaboration and Option Agreement

Partnership combines Protalix's rare disease and biologics expertise with Secarna's AI–powered OligoCreator® platform to jointly develop pharmaceutical candidates for rare renal indications Protalix i...

5 months ago - PRNewsWire

Protalix price target lowered to $12 from $15 at H.C. Wainwright

H.C. Wainwright analyst Raghuram Selvaraju lowered the firm’s price target on Protalix (PLX) to $12 from $15 and keeps a Buy rating on the shares following the Q3 report. The…

6 months ago - TheFly

Protalix BioTherapeutics Earnings Call Transcript: Q3 2025

Nine-month revenues rose 24% year-over-year to $43.6 million, with Q3 net income of $2.4 million. PRX-115 phase II trial is set to begin soon, and cash reserves of $29.4 million are expected to fund operations for at least 12 months.

6 months ago - Transcripts

Protalix BioTherapeutics Reports Third Quarter 2025 Financial and Business Results

Company to host conference call and webcast today at 8:00 a.m. EST CARMIEL, Israel , Nov. 13, 2025 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American: PLX), a biopharmaceutical company focu...

6 months ago - PRNewsWire

Protalix BioTherapeutics to Announce Third Quarter 2025 Financial and Business Results on November 13, 2025

Company to host conference call and webcast at 8:00 a.m. EST CARMIEL, Israel , Nov. 6, 2025 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American: PLX), a biopharmaceutical company focused on ...

6 months ago - PRNewsWire

Chiesi Global Rare Diseases and Protalix BioTherapeutics Seek Re-examination from the EMA for the Negative Opinion for Elfabrio (pegunigalsidase alfa) Alternative Dosing Regimen of Every Four Weeks in the EU

-- Every two weeks remains approved as a dosing regimen of Elfabrio in the EU -- -- Every two weeks remains approved as a dosing regimen of Elfabrio in the EU --

6 months ago - GlobeNewsWire

Protalix, Chiesi Global: CHMP issues negative opinion for Elfabrio

Chiesi Global Rare Diseases, a business unit of the Chiesi Group established to deliver innovative therapies and solutions for people living with rare diseases, and Protalix (PLX) BioTherapeutics ackn...

7 months ago - TheFly

Chiesi Global Rare Diseases and Protalix Biotherapeutics Acknowledge CHMP Negative Opinion on Every Four Week Dosing Regimen of Elfabrio® (pegunigalsidase alfa) in the EU

Every two weeks remains approved as a dosing regimen of Elfabrio in the EU Every two weeks remains approved as a dosing regimen of Elfabrio in the EU

7 months ago - GlobeNewsWire

Protalix BioTherapeutics Transcript: Q3 Investor Summit Group Virtual Conference 2025

The presentation highlighted a unique plant cell technology platform, two approved drugs, and a promising pipeline asset for gout. Key catalysts include an EMA decision on monthly Elfabrio dosing and the start of a pivotal phase II trial for PRX-115, with strong financial footing supporting ongoing operations.

8 months ago - Transcripts

Protalix BioTherapeutics to Present at Investor Summit Virtual

CARMIEL, ISRAEL / ACCESS Newswire / September 11, 2025 / Protalix BioTherapeutics, Inc. (NYSE American:PLX), a biopharmaceutical company focused on the development, production and commercialization of...

8 months ago - Accesswire

Protalix BioTherapeutics to Present at the H.C. Wainwright 27th Annual Global Investment Conference

CARMIEL, Israel, Sept. 2, 2025 /PRNewswire/ -- Protalix BioTherapeutics, Inc. (NYSE American:PLX), a biopharmaceutical company focused on the development, production and commercialization of recombina...

9 months ago - PRNewsWire

Protalix BioTherapeutics Earnings Call Transcript: Q2 2025

Q2 2025 saw a 16% revenue increase and a return to profitability, driven by strong Elfabrio sales to Chiesi and reduced costs. R&D spending doubled in preparation for PRX-115 phase II, and the company expects Elfabrio royalties to exceed $100 million by 2030.

9 months ago - Transcripts