Prime Medicine, Inc. (PRME)

NASDAQ: PRME · Real-Time Price · USD
2.900
+0.125 (4.50%)
At close: Jun 15, 2026, 4:00 PM EDT
3.040
+0.140 (4.83%)
After-hours: Jun 15, 2026, 6:30 PM EDT
Market Cap523.79M +225.2%
Revenue (ttm)4.03M +4.9%
Net Income-198.37M
EPS-1.24
Shares Out 180.62M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume2,699,438
Open2.920
Previous Close2.775
Day's Range2.840 - 3.060
52-Week Range1.414 - 6.940
Beta2.31
AnalystsBuy
Price Target6.92 (+138.62%)
Earnings DateMay 7, 2026

About PRME

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States. Its lead therapeutic product candidate is PM359 for Chronic Granulomatous Disease, which is in Phase 1/2 clinical trial; PM577 for Wilson Disease, that is in preclinical studies; and PM647 to treat genetic disorder caused by mutations in the SERPINA1 gene, resulting in production of misfolded Z-AAT protein that accumulates in the liver and leads to hepatocellular in... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Oct 20, 2022
Employees 146
Stock Exchange NASDAQ
Ticker Symbol PRME
Full Company Profile

Financial Performance

In 2025, Prime Medicine's revenue was $4.63 million, an increase of 55.28% compared to the previous year's $2.98 million. Losses were -$201.14 million, 2.69% more than in 2024.

Financial Statements

Analyst Summary

According to 13 analysts, the average rating for PRME stock is "Buy." The 12-month stock price target is $6.92, which is an increase of 138.62% from the latest price.

Price Target
$6.92
(138.62% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Prime Medicine Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

Prime Editing technology has enabled genetic cures in CGD and is advancing in vivo programs for Wilson Disease and Alpha-1 antitrypsin deficiency, with clinical data expected in 2027. The pipeline leverages modular LNP delivery and differentiated PASSIGE technology, while strong IP and partnerships support financial stability and future growth.

5 days ago - Transcripts

Prime Medicine Transcript: AGM 2026

The meeting confirmed a quorum and approved the election of two directors and the ratification of the audit firm for 2026. No questions were raised by stockholders, and all proposals passed by the required majority.

10 days ago - Transcripts

Prime Medicine Transcript: Jefferies Global Healthcare Conference 2026

Prime Editing technology is advancing with global clinical trials for Wilson's disease and Alpha-1 antitrypsin deficiency, both targeting IND/CTA filings this year and initial data in 2027. Cystic fibrosis and broader liver indications are in preclinical stages, with key catalysts including arbitration resolution and a potential BLA filing for CGD.

11 days ago - Transcripts

Prime Medicine to Present at Goldman Sachs 47th Annual Global Healthcare Conference

CAMBRIDGE, Mass., June 03, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapi...

12 days ago - GlobeNewsWire

Prime Medicine Slides: Corporate presentation

Prime Medicine has posted slides in relation to its latest quarterly earnings report, which was published on June 3, 2026.

12 days ago - Filings

Prime Medicine to Present at Jefferies Global Healthcare Conference

CAMBRIDGE, Mass., May 28, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapie...

18 days ago - GlobeNewsWire

Prime Medicine reports Q1 EPS (28c), consensus (25c)

Reports Q1 revenue $856,000, consensus $844,220. “Prime Medicine (PRME) continues to execute with clear momentum and a focused strategy designed to deliver on the transformative potential of Prime Edi...

5 weeks ago - TheFly

Prime Medicine Reports First Quarter 2026 Financial Results and Provides Business Updates

CAMBRIDGE, Mass., May 07, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapie...

5 weeks ago - GlobeNewsWire

Prime Medicine Quarterly report: Q1 2026

Prime Medicine has published its Q1 2026 quarterly earnings report on May 7, 2026.

5 weeks ago - Filings

Prime Medicine Earnings release: Q1 2026

Prime Medicine released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

5 weeks ago - Filings

Prime Medicine management to meet with Oppenheimer

Meeting to be held on May 11 hosted by Oppenheimer.

5 weeks ago - TheFly

Prime Medicine Proxy statement: Proxy filing

Prime Medicine filed a proxy statement on April 23, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings

Prime Medicine Proxy statement: Proxy filing

Prime Medicine filed a proxy statement on April 23, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings

Prime Medicine appoints Makhni as Chief Financial Officer

Prime Medicine (PRME) announced the appointment of Svetlana Makhni as Chief Financial Officer, CFO. Ms. Makhni will oversee Prime Medicine’s financial operations and strategy, including investor relat...

2 months ago - TheFly

Prime Medicine Appoints Svetlana Makhni as Chief Financial Officer

CAMBRIDGE, Mass., April 16, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therap...

2 months ago - GlobeNewsWire

Oppenheimer bullish on Prime Medicine, initiates with an Outperform

As previously reported, Oppenheimer initiated coverage of Prime Medicine (PRME) with an Outperform rating and $11 price target The firm says Prime is a key name to own in the…

3 months ago - TheFly

Prime Medicine initiated with an Outperform at Oppenheimer

Oppenheimer initiated coverage of Prime Medicine (PRME) with an Outperform rating and $11 price target

3 months ago - TheFly

Prime Medicine Transcript: The Citizens Life Sciences Conference 2026

Two in vivo programs are advancing to the clinic with data expected in 2027, while a revived ex vivo program benefits from regulatory flexibility and reduced costs. Prime Editing's DNA-level correction offers broad applicability, strong safety, and competitive advantages in genetic diseases.

3 months ago - Transcripts

Prime Medicine Transcript: TD Cowen 46th Annual Health Care Conference

The company is advancing its first in vivo liver-directed clinical programs for Wilson disease and alpha-1 antitrypsin deficiency, with regulatory filings expected soon and initial clinical data anticipated in 2027. Strategic partnerships, a strong IP position, and a cash runway into 2027 support a focused pipeline and ongoing business development.

3 months ago - Transcripts

Prime Medicine reports FY25 EPS ($1.35) vs ($1.65) last year

Reports FY25 $4.632M vs $2.983M last year. “We are shaping the future of genetic medicine by advancing a platform that is rapidly emerging as the predominant gene editing technology. With…

3 months ago - TheFly

Prime Medicine Reports Full Year 2025 Financial Results and Provides Business Updates

-- On track to file IND and/or CTA for Wilson Disease and AATD programs in 1H 2026 and mid-2026, respectively; initial clinical data for both expected in 2027 -- -- Ongoing engagement with FDA for PM3...

3 months ago - GlobeNewsWire

Prime Medicine Annual report: Q4 2025

Prime Medicine has published its Q4 2025 annual report on March 3, 2026.

3 months ago - Filings

Prime Medicine Earnings release: Q4 2025

Prime Medicine released its Q4 2025 earnings on March 3, 2026, summarizing the period's financial results.

3 months ago - Filings

Prime Medicine Slides: Corporate presentation

Prime Medicine has posted slides in relation to its latest quarterly earnings report, which was published on March 2, 2026.

3 months ago - Filings

Prime Medicine to Participate in Upcoming Investor Conferences

CAMBRIDGE, Mass., Feb. 25, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapi...

3 months ago - GlobeNewsWire