Spero Therapeutics, Inc. (SPRO)
| Market Cap | 65.51M -47.3% |
| Revenue (ttm) | 47.00M -3.3% |
| Net Income | 7.38M |
| EPS | 0.13 |
| Shares Out | 58.23M |
| PE Ratio | 8.80 |
| Forward PE | n/a |
| Dividend | n/a |
| Ex-Dividend Date | n/a |
| Volume | 210,154 |
| Open | 1.180 |
| Previous Close | 1.140 |
| Day's Range | 1.120 - 1.180 |
| 52-Week Range | 1.040 - 3.080 |
| Beta | 1.50 |
| Analysts | Buy |
| Price Target | 5.00 (+344.44%) |
| Est. Earnings | Nov 12, 2026 |
About SPRO
Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company’s product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, man... [Read more]
Financial Performance
Financial StatementsAnalyst Summary
According to 2 analysts, the average rating for SPRO stock is "Buy." The 12-month stock price target is $5.0, which is an increase of 344.44% from the latest price.
News
Spero Therapeutics initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald initiated coverage of Spero Therapeutics (SPRO) with an Overweight rating and $6 price target Spero has pivoted from antibiotics to immunology and inflammation through its licensing ...
Spero Therapeutics initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald initiated coverage of Spero Therapeutics (SPRO) with an Overweight rating and $6 price target
Spero Therapeutics COO Timothy Keutzer to retire
Spero Therapeutics (SPRO) announced the appointments of Amy Rock as chief regulatory and quality officer and Dae Gon Ha as senior VP, corporate development. The company also announced that Timothy…
Spero Therapeutics Strengthens Leadership Team to Advance Immunology Pipeline
Amy Rock, Ph.D., appointed Chief Regulatory and Quality Officer, bringing extensive experience in global regulatory strategy, clinical development, and with approvals of novel immunotherapies Dae Gon ...
Spero Therapeutics Transcript: Chardan's 10th Annual Healthcare Conference
SP001 is being advanced into a two-dose IgG4-RD phase II trial planned for Q2 2027, targeting disease biology beyond flares. $105 million in non-dilutive financing supports a runway into H2 2029.
Spero Therapeutics to Participate in the Chardan 10th Annual Healthcare Conference
CAMBRIDGE, Mass., Oct. 15, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and...
Russian plague outbreak could boost these under-the-radar pharma stocks
Global biosecurity alarms are flashing after an incident at an anti-plague research facility in Siberia sparked a severe public health response. Following the fatal lab exposure of a researcher in Irk...
Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
CAMBRIDGE, Mass., Oct. 02, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and...
Spero Therapeutics Transcript: H.C. Wainwright 28th Annual Global Investment Conference
SP001’s upstream CD40 ligand mechanism is being advanced for IgG4-related disease, with prior Sjögren’s data supporting continued development. A phase II trial is planned to start in Q2 2027.
Spero Therapeutics price target raised to $6 from $5 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised the firm’s price target on Spero Therapeutics (SPRO) to $6 from $5 and keeps a Buy rating on the shares. The firm cites the…
Spero Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
CAMBRIDGE, Mass., Sept. 03, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology an...
Spero Therapeutics to Present at H.C. Wainwright 28th Annual Global Investment Conference
CAMBRIDGE, Mass., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology an...
Spero Therapeutics files $300M mixed securities shelf
17:05 EDT Spero Therapeutics (SPRO) files $300M mixed securities shelf
Spero Therapeutics Registration statement: Registration filing
Spero Therapeutics filed a registration statement on August 28, 2026, providing details about a securities offering with the SEC.
Spero Therapeutics Earnings Call Transcript: Q2 2026
FDA approved Utebzi, enabling a strategic pivot to immunology with the in-licensing of SP001 and $105M non-dilutive financing. Cash runway now extends into H2 2029, with a phase II trial for SP001 in IgG4-RD planned for 2027.
Spero Therapeutics Quarterly report: Q2 2026
Spero Therapeutics has published its Q2 2026 quarterly earnings report on August 12, 2026.
Spero Therapeutics Earnings release: Q2 2026
Spero Therapeutics released its Q2 2026 earnings on August 12, 2026, summarizing the period's financial results.
Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update
CAMBRIDGE, Mass., Aug. 12, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and...
Spero Therapeutics to Report Second Quarter 2026 Financial Results and Provide Business Update on August 12, 2026
CAMBRIDGE, Mass., Aug. 04, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and...
Spero Therapeutics appoints Debra Jeske Zack as chief medical officer
Spero Therapeutics (SPRO) announced the appointment of Debra Jeske Zack as chief medical officer. Zack will lead Spero’s clinical development strategy and organization as the company advances its immu...
Spero Therapeutics Appoints Debra Jeske Zack, M.D., Ph.D., as Chief Medical Officer
Dr. Zack brings more than 25 years of leadership in developing therapeutics for immune-mediated diseases Appointment strengthens Spero's clinical leadership team as the Company advances SP001, a Phase...
Spero licenses Innovent's experimental immune disease drug for up to $1.1 billion
Spero Therapeutics has licensed rights outside Greater China to develop and commercialize Innovent Biologics' experimental autoimmune disease treatment in a deal worth up to about $1.1 billion, the ...
Spero Therapeutics secures $105M non-dilutive financing to develop SP001
Spero Therapeutics (SPRO) announced a $105M non-recourse non-dilutive royalty financing transaction with affiliates of Healthcare Royalty, a business of KKR. Under the agreement, HCRx will receive a p...
Spero Therapeutics, Innovent Biologics enter license agreement for SP001
Spero Therapeutics (SPRO) and Innovent Biologics (IVBXF) announced an exclusive license agreement for SP001, a third-generation Fc-silent anti-CD40L antibody. Spero will receive exclusive rights to de...
Spero Therapeutics, Innovent Biologics announce exclusive IBI355 license pact
Innovent Biologics and Spero Therapeutics (SPRO) announced an exclusive license agreement for IBI355, a third-generation Fc-silent anti-CD40L antibody. Spero will receive exclusive rights to develop, ...