Spero Therapeutics, Inc. (SPRO)

NASDAQ: SPRO · Real-Time Price · USD
1.440
-0.140 (-8.86%)
Jul 20, 2026, 12:14 PM EDT - Market open
Market Cap83.38M -39.6%
Revenue (ttm)61.19M +37.2%
Net Income15.24M
EPS0.26
Shares Out 57.90M
PE Ratio5.52
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume1,226,734
Open1.570
Previous Close1.580
Day's Range1.410 - 1.570
52-Week Range1.430 - 3.080
Beta1.49
Analystsn/a
Price Targetn/a
Earnings DateAug 11, 2026

About SPRO

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company’s product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, man... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 2, 2017
Employees 25
Stock Exchange NASDAQ
Ticker Symbol SPRO
Full Company Profile

Financial Performance

Financial Statements

News

Spero licenses Innovent's experimental immune disease drug for up to $1.1 billion

Spero Therapeutics has licensed rights outside Greater China to develop and commercialize Innovent Biologics' ​experimental autoimmune disease treatment in a deal worth ‌up to about $1.1 billion, the ...

6 days ago - Reuters

Spero Therapeutics secures $105M non-dilutive financing to develop SP001

Spero Therapeutics (SPRO) announced a $105M non-recourse non-dilutive royalty financing transaction with affiliates of Healthcare Royalty, a business of KKR. Under the agreement, HCRx will receive a p...

6 days ago - TheFly

Spero Therapeutics, Innovent Biologics enter license agreement for SP001

Spero Therapeutics (SPRO) and Innovent Biologics (IVBXF) announced an exclusive license agreement for SP001, a third-generation Fc-silent anti-CD40L antibody. Spero will receive exclusive rights to de...

6 days ago - TheFly

Spero Therapeutics, Innovent Biologics announce exclusive IBI355 license pact

Innovent Biologics and Spero Therapeutics (SPRO) announced an exclusive license agreement for IBI355, a third-generation Fc-silent anti-CD40L antibody. Spero will receive exclusive rights to develop, ...

6 days ago - TheFly

Spero Therapeutics Announces $105 Million Non-Recourse Non-Dilutive Financing Backed by a Portion of Utebzi Milestones & Royalties

CAMBRIDGE, Mass., July 14, 2026 (GLOBE NEWSWIRE) --  Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology an...

6 days ago - GlobeNewsWire

Innovent Biologics and Spero Therapeutics Announce Exclusive License for IBI355 (SP001), a Phase 2-Ready Third-Generation Anti-CD40L Antibody

Under the terms of the agreement, Spero will receive exclusive global rights, excluding Greater China, to develop, research, manufacture, and commercialize IBI355 (Spero R&D code: SP001) Innovent will...

6 days ago - PRNewsWire

Spero Therapeutics and Innovent Biologics Announce Exclusive License for SP001 (IBI355), a Phase 2-Ready Third-Generation Anti-CD40L Antibody

CAMBRIDGE, Mass. and SAN FRANCISCO and SUZHOU, China, July 14, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO) and Innovent Biologics, Inc. (01801.HK) today announced an exclusive lic...

6 days ago - GlobeNewsWire

Spero Therapeutics Slides: Company presentation

Spero Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on July 13, 2026.

7 days ago - Filings

Avacta Appoints Healthcare Executive Patrick Vink as Deputy Chairman of the Board of Directors

LONDON and PHILADELPHIA, July 08, 2026 (GLOBE NEWSWIRE) -- Avacta Therapeutics (AIM: AVCT, "the Company", "Avacta"), a clinical stage biopharmaceutical company developing pre|CISION®, a tumor-activate...

12 days ago - GlobeNewsWire

Spero Therapeutics Transcript: AGM 2026

The meeting covered director elections, auditor ratification, executive compensation, an increase in authorized shares, and a new stock incentive plan. All proposals passed with a quorum present, and voting results will be published in a Form 8-K.

27 days ago - Transcripts

Utebzi (tebipenem pivoxil) approved in the US for adults with complicated urinary tract infections (cUTIs)

PHILADELPHIA--(BUSINESS WIRE)--GSK plc (LSE/NYSE: GSK) and Spero Therapeutics (Nasdaq: SPRO) today announced that the US Food and Drug Administration (FDA) has approved Utebzi, an oral antibiotic for ...

Other symbols: GSK
4 weeks ago - Business Wire

GSK, Spero Therapeutics announce FDA approval of Utebzi

GSK plc (GSK) and Spero Therapeutics (SPRO) announced that the Food and Drug Administration has approved Utebzi, an oral antibiotic for the treatment of complicated urinary tract infections including ...

Other symbols: GSK
4 weeks ago - TheFly

Spero Therapeutics Announces First Quarter 2026 Operating Results and Provides Business Update

New Drug Application (NDA) for tebipenem HBr for complicated urinary tract infections (cUTI), including pyelonephritis, is under review at the FDA, with PDUFA date of June 18, 2026 Spero maintains its...

2 months ago - GlobeNewsWire

Spero Therapeutics Earnings release: Q1 2026

Spero Therapeutics released its Q1 2026 earnings on May 13, 2026, summarizing the period's financial results.

2 months ago - Filings

Spero Therapeutics Quarterly report: Q1 2026

Spero Therapeutics has published its Q1 2026 quarterly earnings report on May 13, 2026.

2 months ago - Filings

Spero Therapeutics to Report First Quarter 2026 Financial Results and Provide Business Update on May 13, 2026

CAMBRIDGE, Mass., May 05, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics , Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare ...

2 months ago - GlobeNewsWire

Spero Therapeutics Proxy statement: Proxy filing

Spero Therapeutics filed a proxy statement on April 27, 2026, providing details for shareholder voting and corporate governance matters.

3 months ago - Filings

Spero Therapeutics Proxy statement: Proxy filing

Spero Therapeutics filed a proxy statement on April 27, 2026, providing details for shareholder voting and corporate governance matters.

3 months ago - Filings

Spero Therapeutics Proxy statement: Proxy filing

Spero Therapeutics filed a proxy statement on April 13, 2026, providing details for shareholder voting and corporate governance matters.

3 months ago - Filings

Spero Therapeutics Announces Fourth Quarter and Full Year 2025 Operating Results and Provides a Business Update

CAMBRIDGE, Mass., March 26, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare...

4 months ago - GlobeNewsWire

Spero Therapeutics Earnings release: Q4 2025

Spero Therapeutics released its Q4 2025 earnings on March 26, 2026, summarizing the period's financial results.

4 months ago - Filings

Spero Therapeutics Annual report: Q4 2025

Spero Therapeutics has published its Q4 2025 annual report on March 26, 2026.

4 months ago - Filings

Spero Therapeutics to Report Fourth Quarter and Full Year 2025 Financial Results and Provide Business Update on March 26, 2026

CAMBRIDGE, Mass., March 18, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare...

4 months ago - GlobeNewsWire

Spero announces GSK filed NDA resubmission to FDA for tebipenem HBr

Spero Therapeutics (SPRO) announced that its development partner, GSK (GSK), filed a New Drug Application, NDA, resubmission to the U.S. Food and Drug Administration, FDA, for tebipenem HBr, an invest...

Other symbols: GSK
7 months ago - TheFly

Spero Announces NDA Resubmission of Tebipenem HBr by GSK to the FDA for the Treatment of Complicated Urinary Tract Infections, Including Pyelonephritis

CAMBRIDGE, Mass., Dec. 19, 2025 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on identifying and developing novel treatments for rare ...

7 months ago - GlobeNewsWire