Spero Therapeutics, Inc. (SPRO)

Spero Therapeutics Revenue

Spero Therapeutics had revenue of $47.00M in the twelve months ending June 30, 2026, down -3.25% year-over-year. In the year 2025, Spero Therapeutics had annual revenue of $66.80M with 39.24% growth. That makes Spero Therapeutics the 28,392nd largest company in the world by revenue and 3,824th in the United States.

• Revenue (ttm): $47.00M
• Revenue Growth: -3.25%
• P/S Ratio: 1.45
• Revenue / Employee: $1,879,880
• Employees: 25
• Market Cap: 65.22M

Revenue Chart

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Revenue History

Fiscal Year End	Revenue	Change	Growth
Dec 31, 2025	66.80M	18.83M	39.24%
Dec 31, 2024	47.98M	-55.80M	-53.77%
Dec 31, 2023	103.78M	50.27M	93.95%
Dec 31, 2022	53.51M	35.25M	193.10%
Dec 31, 2021	18.26M	8.93M	95.67%
Dec 31, 2020	9.33M	-8.82M	-48.59%
Dec 31, 2019	18.15M	14.18M	357.56%
Dec 31, 2018	3.97M	1.99M	100.40%
Dec 31, 2017	1.98M	1.64M	490.75%
Dec 31, 2016	335.00K	-	-
Dec 31, 2015	-	-	-

Data Source: Fiscal.ai Last updated: Aug 12, 2026

Revenue data is provided by Fiscal.ai and updates within minutes after each earnings release, which is every three months for this company.

Update frequency:

Quarterly

Last checked:

Oct 28, 2026

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