Spero Therapeutics, Inc. (SPRO)

Spero Therapeutics Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Mar 4, 2026	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Market Cap	127	56	78	91	621	567
Market Cap Growth	185.50%	-27.82%	-14.15%	-85.38%	9.38%	207.32%
Enterprise Value	78.12	7.64	7.12	-11.71	529.91	448.29
Last Close Price	2.25	1.03	1.47	1.73	16.01	19.39
PE Ratio	-	-0.81	3.42	-1.41	-5.50	-5.51
Forward PE	4.59	-	-	-	-	-
PS Ratio	3.04	1.17	0.75	1.70	33.99	60.81
PB Ratio	4.65	1.22	0.73	1.20	7.03	4.30
P/TBV Ratio	4.72	1.21	0.73	0.86	5.60	3.29
P/FCF Ratio	-	-2.40	-2.36	-11.74	-9.64	-6.59
P/OCF Ratio	-	-2.40	-2.36	-11.74	-9.64	-6.61
EV/Sales Ratio	1.93	0.16	0.07	-0.22	29.03	48.05
EV/EBITDA Ratio	-	-0.10	0.33	0.28	-6.07	-5.72
EV/EBIT Ratio	-	-0.10	0.33	0.28	-6.02	-5.67
EV/FCF Ratio	-	-0.33	-0.22	1.51	-8.24	-5.21
Debt / Equity Ratio	0.13	0.09	0.05	0.09	0.63	0.06
Debt / EBITDA Ratio	-0.07	-0.06	0.25	-0.16	-0.64	-0.10
Debt / FCF Ratio	-0.12	-0.18	-0.17	-0.86	-0.87	-0.09
Net Debt / Equity Ratio	-1.71	-1.05	-0.66	-1.35	-1.03	-0.90
Net Debt / EBITDA Ratio	0.97	0.66	-3.24	2.48	1.04	1.52
Net Debt / FCF Ratio	1.64	2.07	2.15	13.25	1.41	1.38
Asset Turnover	0.49	0.33	0.68	0.36	0.11	0.07
Quick Ratio	3.74	2.15	4.67	5.09	7.98	9.28
Current Ratio	3.83	2.19	3.53	5.25	8.46	9.70
Return on Equity (ROE)	-119.13%	-89.62%	30.63%	-56.53%	-81.47%	-75.77%
Return on Assets (ROA)	-56.47%	-50.09%	15.42%	-28.52%	-54.22%	-60.96%
Return on Invested Capital (ROIC)	-321.01%	-112.22%	45.44%	-550.73%	-786.58%	-1379.24%
Return on Capital Employed (ROCE)	-91.81%	-70.98%	17.30%	-33.02%	-60.36%	-72.40%
Earnings Yield	-35.53%	-123.30%	29.25%	-71.10%	-18.18%	-18.15%
FCF Yield	-22.43%	-41.69%	-42.35%	-8.52%	-10.37%	-15.16%
Buyback Yield / Dilution	-	0.00%	-0.28%	-27.47%	-13.95%	-14.25%

Updated Sep 30, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q