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Spero Therapeutics, Inc. (SPRO)
NASDAQ: SPRO · Real-Time Price · USD
2.680
+0.040 (1.52%)
Apr 16, 2026, 4:00 PM EDT - Market closed

Spero Therapeutics Ratios and Metrics

Millions USD. Fiscal year is Jan - Dec.
Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Apr '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Market Cap
155131567891621
Market Cap Growth
285.94%133.76%-27.82%-14.15%-85.38%9.38%
Enterprise Value
117.7892.125.895.4-13.4528.55
Last Close Price
2.682.331.031.471.7316.01
PE Ratio
17.8715.53-0.813.42-1.41-5.50
Forward PE
4.004.88----
PS Ratio
2.321.971.170.751.7033.99
PB Ratio
2.562.231.220.731.207.03
P/TBV Ratio
2.582.331.210.730.865.60
P/FCF Ratio
--10.41-2.40-2.36-11.74-9.64
P/OCF Ratio
--10.41-2.40-2.36-11.74-9.64
EV/Sales Ratio
1.761.380.120.05-0.2528.95
EV/EBITDA Ratio
16.4514.59-0.080.250.32-6.05
EV/EBIT Ratio
16.4514.59-0.080.250.32-6.01
EV/FCF Ratio
--7.30-0.25-0.161.73-8.21
Debt / Equity Ratio
0.020.020.060.040.070.62
Debt / EBITDA Ratio
0.460.46-0.060.25-0.16-0.64
Debt / FCF Ratio
-0.23-0.23-0.18-0.17-0.86-0.87
Net Debt / Equity Ratio
-0.63-0.63-1.05-0.66-1.35-1.03
Net Debt / EBITDA Ratio
-5.92-5.920.66-3.242.481.04
Net Debt / FCF Ratio
2.962.962.072.1513.251.41
Asset Turnover
0.740.740.330.680.360.11
Quick Ratio
7.407.402.154.675.097.98
Current Ratio
7.597.592.193.535.258.46
Return on Equity (ROE)
17.30%17.30%-89.62%30.63%-56.53%-81.47%
Return on Assets (ROA)
7.24%7.24%-50.09%15.42%-28.52%-54.22%
Return on Invested Capital (ROIC)
23.64%23.64%-112.22%45.44%-550.73%-786.58%
Return on Capital Employed (ROCE)
10.39%10.39%-70.98%17.30%-33.02%-60.36%
Earnings Yield
5.53%6.44%-123.30%29.25%-71.10%-18.18%
FCF Yield
-8.14%-9.60%-41.69%-42.35%-8.52%-10.37%
Buyback Yield / Dilution
-9.26%-9.26%-1.98%-40.98%-21.65%-38.01%
Total Shareholder Return
-9.26%-9.26%-1.98%-40.98%-21.65%-38.01%
Updated Dec 31, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.
SEC Filings: 10-K · 10-Q