VYNE Therapeutics Inc. (VYNE)

NASDAQ: VYNE · Real-Time Price · USD
0.6715
-0.0051 (-0.75%)
May 21, 2026, 1:57 PM EDT - Market open
Market Cap22.38M +9.0%
Revenue (ttm)454,000 -25.0%
Net Income-21.46M
EPS-0.50
Shares Out 33.32M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume66,026
Open0.6623
Previous Close0.6766
Day's Range0.6600 - 0.6823
52-Week Range0.2805 - 1.9600
Beta2.00
AnalystsBuy
Price Target2.00 (+197.84%)
Earnings DateMay 15, 2026

About VYNE

VYNE Therapeutics Inc., a clinical-stage biopharmaceutical company, focuses on developing therapies to treat chronic inflammatory and immune-mediated conditions. The company’s lead program is repibresib gel (VYN201), a topically administered small molecule pan-bromodomain and extra-terminal (BET) inhibitor soft drug to address diseases involving multiple and diverse inflammatory cell signaling pathways with low systemic exposure. It also develops VYN202, a BD2-selective oral small molecule BET inhibitor in Phase 1b trial for the acute control a... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jan 25, 2018
Employees 10
Stock Exchange NASDAQ
Ticker Symbol VYNE
Full Company Profile

Financial Performance

In 2025, VYNE Therapeutics's revenue was $570,000, an increase of 13.77% compared to the previous year's $501,000. Losses were -$26.48 million, -33.52% less than in 2024.

Financial Statements

Analyst Summary

According to 3 analysts, the average rating for VYNE stock is "Buy." The 12-month stock price target is $2.0, which is an increase of 197.84% from the latest price.

Price Target
$2.0
(197.84% upside)
Analyst Consensus: Buy
Stock Forecasts

News

VYNE Therapeutics Quarterly report: Q1 2026

VYNE Therapeutics has published its Q1 2026 quarterly earnings report on May 15, 2026.

6 days ago - Filings

VYNE Therapeutics Annual report: Q4 2025

VYNE Therapeutics has published its Q4 2025 annual report on February 27, 2026.

2 months ago - Filings

VYNE Therapeutics Transcript: M&A Announcement

VYNE and Yarrow Bioscience will merge, creating a Nasdaq-listed company focused on advancing YB-101, a first-in-class TSHR antibody for Graves' disease and TED. The combined entity is well-funded, with a strong investor syndicate and a cash runway into 2028.

5 months ago - Transcripts

VYNE Therapeutics Press release: M&A Announcement

VYNE Therapeutics issued a press release on December 17, 2025, disclosing material business information to investors.

5 months ago - Filings

VYNE Therapeutics, Yarrow Bioscience enter merger agreement

VYNE Therapeutics (VYNE) and Yarrow Bioscience entered into a definitive merger agreement pursuant to which the companies will combine in an all-stock transaction. Upon completion of the Merger, the c...

5 months ago - TheFly

VYNE Therapeutics and Yarrow Bioscience Announce Merger Agreement

NEW YORK, Dec. 17, 2025 (GLOBE NEWSWIRE) -- VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE”) and Yarrow Bioscience, Inc. (“Yarrow”) today announced that they have entered into a definitive merger agreem...

5 months ago - GlobeNewsWire

VYNE Therapeutics Proxy statement: Proxy Filing

VYNE Therapeutics filed a proxy statement on November 12, 2025, providing details for shareholder voting and corporate governance matters.

6 months ago - Filings

VYNE Therapeutics reports Q3 EPS (17c) vs (29c) last year

Reports Q3 revenue $169k vs $121k last year. “Consistent with our focus on growing shareholder value, we have made considerable progress in evaluating a number of potential value-creating opportunitie...

7 months ago - TheFly

VYNE Therapeutics Reports 2025 Third Quarter Financial Results and Provides Business Update

Company is progressing its previously initiated strategic review evaluating a range of options to maximize shareholder value, including assessment of internal pipeline opportunities and broader strate...

7 months ago - GlobeNewsWire

VYNE Therapeutics Quarterly report: Q3 2025

VYNE Therapeutics has published its Q3 2025 quarterly earnings report on November 6, 2025.

7 months ago - Filings

VYNE Therapeutics Earnings release: Q3 2025

VYNE Therapeutics released its Q3 2025 earnings on November 6, 2025, summarizing the period's financial results.

7 months ago - Filings

VYNE Therapeutics reports Q2 EPS (13c) vs (22c) last year

Reports Q2 revenue $69,000 vs $198,000 last year. “The strength of our recent clinical and preclinical findings for VYN202 provides a compelling scientific foundation as we determine the best path…

10 months ago - TheFly

VYNE Therapeutics Reports 2025 Second Quarter Financial Results and Provides Business Update

BRIDGEWATER, N.J., Aug. 14, 2025 (GLOBE NEWSWIRE) -- VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”), a clinical-stage biopharmaceutical company focused on developing differentiated th...

10 months ago - GlobeNewsWire

VYNE Therapeutics Quarterly report: Q2 2025

VYNE Therapeutics has published its Q2 2025 quarterly earnings report on August 14, 2025.

10 months ago - Filings

VYNE Therapeutics Earnings release: Q2 2025

VYNE Therapeutics released its Q2 2025 earnings on August 14, 2025, summarizing the period's financial results.

10 months ago - Filings

Why Is VYNE Therapeutics Stock (VYNE) Down 70% Today?

VYNE Therapeutics stock plummeted on Wednesday after a Phase 2b trial missed its primary endpoint.

10 months ago - TipRanks

VYNE Therapeutics downgraded to Neutral from Buy at BTIG

BTIG analyst Julien Harrison downgraded VYNE Therapeutics (VYNE) to Neutral from Buy with no price target after the company’s Phase 2b trial assessing repibresib in nonsegmental vitiligo did not achie...

10 months ago - TheFly

VYNE Therapeutics downgraded at H.C. Wainwright after vitiligo trial miss

H.C. Wainwright downgraded VYNE Therapeutics (VYNE) to Neutral from Buy and removed the firm’s prior $4.50 price target after the company’s Phase 2b trial assessing repibresib in nonsegmental vitiligo...

10 months ago - TheFly

VYNE Therapeutics downgraded to Neutral from Buy at H.C. Wainwright

H.C. Wainwright analyst Joseph Pantginis downgraded VYNE Therapeutics (VYNE) to Neutral from Buy.

10 months ago - TheFly

VYNE says Phase 2B trial with repibresib gel did not meet primary endpoint

VYNE Therapeutics (VYNE) announced topline results from its Phase 2b trial evaluating Repibresib gel in nonsegmental vitiligo. The trial, which evaluated 177 subjects, did not meet its primary endpoin...

10 months ago - TheFly

VYNE Therapeutics Announces Topline Results from Phase 2b Trial with Repibresib Gel in Nonsegmental Vitiligo

Trial Did Not Meet Primary Endpoint or Key Secondary Endpoint of F-VASI50 and F-VASI75 Nominally Statistically Significant Effects Observed in Key Secondary and Exploratory Endpoints of Change from Ba...

10 months ago - GlobeNewsWire

H.C. Wainwright ‘encouraged’ by VYNE Therapeutics VYN202 update

After VYNE Therapeutics (VYNE) provided an update on its VYN202 program following the recent FDA clinical hold on the Phase 1b trial in moderate-to-severe plaque psoriasis, H.C. Wainwright notes that…

11 months ago - TheFly

VYNE Therapeutics provides program update on VYN202 following clinical hold

VYNE Therapeutics (VYNE) provided a program update for VYN202 following the clinical hold issued by the U.S. Food and Drug Administration in April for the Company’s Phase 1b clinical trial…

11 months ago - TheFly

VYNE Therapeutics Provides Program Update on Oral BET inhibitor VYN202

BRIDGEWATER, N.J., July 02, 2025 (GLOBE NEWSWIRE) -- VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”), a clinical-stage biopharmaceutical company focused on developing differentiated th...

11 months ago - GlobeNewsWire

VYNE Therapeutics reports Q1 EPS (20c) vs (15c) last year

Reports Q1 revenue $200k vs $100k last year. “During the first quarter of 2025, we continued to progress our Phase 2b trial evaluating repibresib for the treatment of vitiligo, and…

1 year ago - TheFly