| 1 | RPRX | Royalty Pharma plc | 5.21% |
| 2 | ALNY | Alnylam Pharmaceuticals, Inc. | 5.19% |
| 3 | AMGN | Amgen Inc. | 5.17% |
| 4 | ILMN | Illumina, Inc. | 5.15% |
| 5 | VRTX | Vertex Pharmaceuticals Incorporated | 4.99% |
| 6 | GILD | Gilead Sciences, Inc. | 4.93% |
| 7 | BMRN | BioMarin Pharmaceutical Inc. | 4.73% |
| 8 | UTHR | United Therapeutics Corporation | 4.40% |
| 9 | BPMC | Blueprint Medicines Corporation | 3.41% |
| 10 | PTGX | Protagonist Therapeutics, Inc. | 3.24% |
| 11 | AVXL | Anavex Life Sciences Corp. | 2.91% |
| 12 | QGEN | Qiagen N.V. | 2.87% |
| 13 | PTCT | PTC Therapeutics, Inc. | 2.86% |
| 14 | CDNA | CareDx, Inc | 2.81% |
| 15 | DVAX | Dynavax Technologies Corporation | 2.80% |
| 16 | RGEN | Repligen Corporation | 2.78% |
| 17 | INCY | Incyte Corporation | 2.77% |
| 18 | ARWR | Arrowhead Pharmaceuticals, Inc. | 2.73% |
| 19 | TGTX | TG Therapeutics, Inc. | 2.73% |
| 20 | NBIX | Neurocrine Biosciences, Inc. | 2.71% |
| 21 | HALO | Halozyme Therapeutics, Inc. | 2.65% |
| 22 | COLL | Collegium Pharmaceutical, Inc. | 2.64% |
| 23 | ACAD | ACADIA Pharmaceuticals Inc. | 2.61% |
| 24 | FOLD | Amicus Therapeutics, Inc. | 2.58% |
| 25 | EXEL | Exelixis, Inc. | 2.57% |
| View PBE holdings |