Silence Therapeutics plc (SLNCF)

OTCMKTS · Delayed Price · Currency is USD
1.060
0.00 (0.00%)
May 26, 2026, 9:30 AM EST
Market Cap313.64M +79.5%
Revenue (ttm)839.00K -97.0%
Net Income-75.04M
EPS-1.61
Shares Out n/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volumen/a
Open1.060
Previous Close1.060
Day's Range1.060 - 1.060
52-Week Range1.060 - 2.630
Beta1.52
Analystsn/a
Price Targetn/a
Earnings DateAug 6, 2026

About Silence Therapeutics

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN3... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 1994
Employees 88
Stock Exchange OTCMKTS
Ticker Symbol SLNCF
Full Company Profile

Financial Performance

In 2025, Silence Therapeutics's revenue was $559,000, a decrease of -98.71% compared to the previous year's $43.26 million. Losses were -$88.61 million, 95.6% more than in 2024.

Financial Statements

News

Silence Therapeutics Transcript: H.C. Wainwright 4th Annual BioConnect Investor Conference

The company is advancing a robust siRNA pipeline targeting cardiometabolic and hematological diseases, with key milestones expected for divesiran (polycythemia vera) and zerlasiran (Lp(a)) in 2026. Strong clinical execution, differentiated technology, and a growing early-stage pipeline position it for significant data-driven progress over the next year.

7 days ago - Transcripts

Silence Therapeutics files $300M ordinary shares offering

16:11 EDT Silence Therapeutics (SLN) files $300M ordinary shares offering

8 days ago - TheFly

Silence Therapeutics Registration statement: Registration filing

Silence Therapeutics filed a registration statement on May 18, 2026, providing details about a securities offering with the SEC.

9 days ago - Filings

Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that...

15 days ago - Business Wire

Silence Therapeutics price target lowered to $27 from $35 at Chardan

Chardan analyst Keay Nakae lowered the firm’s price target on Silence Therapeutics (SLN) to $27 from $35 and keeps a Buy rating on the shares. The firm updated the company’s…

19 days ago - TheFly

Silence Therapeutics reports Q1 EPS (11c) vs. (20c) last year

Reports revenue $422,000 vs. $142,000 last year, “The Silence team continues to advance research supporting the broad potential of our mRNAi GOLD platform, and we remain well positioned as we…

20 days ago - TheFly

Silence Therapeutics Highlights Recent Business Achievements and Reports First Quarter 2026 Financial Results

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

20 days ago - Business Wire

Silence Therapeutics Earnings release: Q1 2026

Silence Therapeutics released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

20 days ago - Filings

Silence Therapeutics Quarterly report: Q1 2026

Silence Therapeutics has published its Q1 2026 quarterly earnings report on May 7, 2026.

20 days ago - Filings

Silence Therapeutics Slides: Corporate presentation

Silence Therapeutics has posted slides in relation to its latest quarterly earnings report, which was published on May 6, 2026.

21 days ago - Filings

Silence Therapeutics Proxy statement: Proxy filing

Silence Therapeutics filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Silence Therapeutics Highlights Recent Business Achievements and Reports Fourth Quarter and Full Year 2025 Financial Results

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN, a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported financ...

2 months ago - Business Wire

Silence Therapeutics Annual report: Q4 2025

Silence Therapeutics has published its Q4 2025 annual report on March 5, 2026.

2 months ago - Filings

Silence Therapeutics Earnings release: Q4 2025

Silence Therapeutics released its Q4 2025 earnings on March 5, 2026, summarizing the period's financial results.

2 months ago - Filings

Silence Therapeutics Annual report: Q4 2025

Silence Therapeutics has published its Q4 2025 annual report on March 5, 2026.

2 months ago - Filings

Silence Therapeutics CEO Craig Tooman to end employment

Silence Therapeutics (SLN) announced that Craig Tooman, who has served as the company’s president, CEO and board member since 2022, agreed by mutual consent to end his employment with the…

5 months ago - TheFly

Silence Therapeutics Announces Leadership Changes

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

5 months ago - Business Wire

Silence Therapeutics Transcript: Jefferies London Healthcare Conference 2025

A proprietary siRNA platform supports three clinical programs, including phase II SLN124 for polycythemia vera and phase III-ready SLN360 for Lp(a), both showing robust efficacy and differentiated dosing. Key milestones include phase II data in Q3 2025 and strong financial runway into 2028.

6 months ago - Transcripts

Silence Therapeutics to Participate in Fireside Chat at Jefferies Global Healthcare Conference

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that...

7 months ago - Business Wire

Silence Therapeutics reports Q3 EPS (15c), consensus (21c)

Reports Q3 revenue $159,000, consensus $3.28M. “Silence continues to focus on operational execution, highlighted by the rapid achievement of full enrollment in our ongoing SANRECO Phase 2 study of div...

7 months ago - TheFly

Silence Therapeutics Reports Third Quarter 2025 Financial Results and Recent Business Highlights

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) the...

7 months ago - Business Wire

Silence Therapeutics Quarterly report: Q3 2025

Silence Therapeutics has published its Q3 2025 quarterly earnings report on November 6, 2025.

7 months ago - Filings

Silence Therapeutics Earnings release: Q3 2025

Silence Therapeutics released its Q3 2025 earnings on November 6, 2025, summarizing the period's financial results.

7 months ago - Filings

Silence Therapeutics completes patient enrollment in SANRECO

Silence Therapeutics (SLN) announced it has completed patient enrollment in the SANRECO Phase 2 study of divesiran, a first-in-class siRNA targeting TMPRSS6, for the treatment of polycythemia vera. In...

7 months ago - TheFly

Silence Therapeutics Completes Enrollment in SANRECO Phase 2 Study of Divesiran for Polycythemia Vera (PV)

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced it h...

7 months ago - Business Wire