Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · Real-Time Price · USD
35.63
+0.04 (0.11%)
At close: Dec 20, 2024, 4:00 PM
35.50
-0.13 (-0.36%)
After-hours: Dec 20, 2024, 6:32 PM EST
0.11%
Market Cap 5.63B
Revenue (ttm) 803.07M
Net Income (ttm) -358.81M
Shares Out 157.90M
EPS (ttm) -2.46
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 3,594,437
Open 35.86
Previous Close 35.59
Day's Range 35.05 - 36.39
52-Week Range 33.33 - 54.44
Beta 0.36
Analysts Buy
Price Target 62.00 (+74.01%)
Earnings Date Feb 19, 2025

About IONS

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 17, 1991
Employees 927
Stock Exchange NASDAQ
Ticker Symbol IONS
Full Company Profile

Financial Performance

In 2023, Ionis Pharmaceuticals's revenue was $787.65 million, an increase of 34.10% compared to the previous year's $587.37 million. Losses were -$366.29 million, 35.8% more than in 2022.

Financial Statements

Analyst Forecast

According to 18 analysts, the average rating for IONS stock is "Buy." The 12-month stock price forecast is $62.0, which is an increase of 74.01% from the latest price.

Price Target
$62.0
(74.01% upside)
Analyst Consensus: Buy
Stock Forecasts

News

FDA Approves Ionis Pharmaceuticals' Rare Genetic Disease Therapy to Lower High-Level Of Fat In Blood

On Thursday, the FDA approved Ionis Pharmaceuticals, Inc.'s IONS Tryngolza (olezarsen) as an adjunct to diet to reduce triglycerides in adults with familial chylomicronemia syndrome (FCS), a rare, gen...

1 day ago - Benzinga

TRYNGOLZA™ (olezarsen) approved in U.S. as first-ever treatment for adults living with familial chylomicronemia syndrome as an adjunct to diet

TRYNGOLZA shown to significantly reduce triglycerides and substantially reduce acute pancreatitis events in adults with FCS; a rare, highly debilitating and life-threatening disease Indicated for adul...

1 day ago - PRNewsWire

US FDA approves Ionis Pharma's genetic disorder drug

The U.S. Food and Drug Administration has approved Ionis Pharmaceuticals' drug to treat a rare genetic disorder, making it the company's first wholly-owned drug, the health regulator's website showed ...

1 day ago - Reuters

Ionis to present at upcoming investor conferences

CARLSBAD, Calif. , Nov. 7, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Gug...

6 weeks ago - PRNewsWire

Ionis Pharmaceuticals, Inc. (IONS) Q3 2024 Earnings Call Transcript

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Q3 2024 Earnings Conference Call November 6, 2024 11:30 AM ET Company Participants Wade Walke – Senior Vice President of Investor Relations Brett Monia – Chi...

6 weeks ago - Seeking Alpha

Ionis Announces Pivotal Phase 3 Trial Design for ION582 in Angelman Syndrome

Positive End of Phase 2 discussion with FDA, including alignment on Phase 3 design Bayley-4 expressive communication selected as Phase 3 study primary endpoint Initiation of ION582 Phase 3 study plann...

6 weeks ago - PRNewsWire

Ionis reports third quarter 2024 financial results

WAINUA TM  U.S. launch progressing well; approved in UK; positive CHMP opinion Olezarsen FCS PDUFA December 19, 2024 Donidalorsen HAE PDUFA August 21, 2025; EU regulatory submission in process On trac...

6 weeks ago - PRNewsWire

Ionis announces FDA acceptance of New Drug Application for donidalorsen for prophylactic treatment of HAE

Donidalorsen will be a first-in-class RNA-targeted medicine for hereditary angioedema, assuming approval Donidalorsen PDUFA date set for August 21, 2025 Donidalorsen has the potential to be Ionis' sec...

6 weeks ago - PRNewsWire

Ionis Pharmaceuticals: Catalysts Due In 2025/2026 Are Extremely Compelling

Ionis is a promising biotech with a strong late-stage pipeline and lucrative Big Pharma partnerships, despite current weak commercial revenues and heavy losses. The company has five FDA-approved drugs...

2 months ago - Seeking Alpha

Ionis to hold third quarter 2024 financial results webcast

Webcast scheduled for Wednesday, November 6 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

2 months ago - PRNewsWire

WAINZUA (eplontersen) recommended for approval in the EU by CHMP for the treatment of adults with polyneuropathy associated with hereditary transthyretin-mediated amyloidosis

- Recommendation based on NEURO-TTRansform Phase 3 results showing WAINZUA demonstrated consistent and sustained benefit improving neuropathy impairment and quality of life versus placebo CARLSBAD, Ca...

2 months ago - PRNewsWire

New positive donidalorsen data to be presented at 2024 American College of Allergy, Asthma & Immunology (ACAAI) Annual Scientific Meeting

–   Data continue to demonstrate donidalorsen potential to deliver significant and sustained reductions in HAE attacks up to three years with monthly or every two-month dosing CARLSBAD, Calif. , Oct. ...

2 months ago - PRNewsWire

Zilganersen granted U.S. FDA Fast Track designation for people living with Alexander disease

Zilganersen is the first investigational medicine in clinical development for adults and children living with Alexander disease, an ultra-rare neurological condition CARLSBAD, Calif. , Oct. 1, 2024 /P...

2 months ago - PRNewsWire

Rubrik Reports Q2 Results, Joins Ionis Pharmaceuticals, Hewlett Packard Enterprise And Other Big Stocks Moving Lower In Tuesday's Pre-Market Session

U.S. stock futures were slightly lower this morning, with the Dow futures falling around 0.1% on Tuesday.

Other symbols: HPERBRK
3 months ago - Benzinga

Ionis announces pricing of $500.3 million public offering

CARLSBAD, Calif. , Sept. 9, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced the pricing of an underwritten public offering of 11,500,000 shares of its common stock.

3 months ago - PRNewsWire

Ionis announces proposed public offering of common stock

CARLSBAD, Calif. , Sept. 9, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced a proposed underwritten public offering of $500.0 million of its common stock.

3 months ago - PRNewsWire

Ionis Pharmaceuticals: Harnessing RNA-Targeted Therapies For Long-Term Shareholder Value

Ionis Pharmaceuticals specializes in RNA-targeted therapies for neurological and cardiometabolic diseases using antisense DNA technology. The company has a robust pipeline with over 40 drug candidates...

4 months ago - Seeking Alpha

Ionis Pharmaceuticals, Inc. (IONS) Q2 2024 Earnings Call Transcript

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Q2 2024 Earnings Conference Call August 1, 2024 11:30 AM ET Company Participants Wade Walke - Senior Vice President of Investor Relations Brett Monia - Chief...

5 months ago - Seeking Alpha

Ionis reports second quarter 2024 financial results

WAINUA TM  U.S. launch progressing well; approved in Canada; EU approval decision expected this year Olezarsen PDUFA December 19, 2024 for FCS Positive Phase 3 donidalorsen data for HAE; preparing U.S...

5 months ago - PRNewsWire

Alcyone Therapeutics Announces Continued Enrollment Approval from FDA of the PIERRE Pivotal IDE Clinical Study of the ThecaFlex DRx™ System for Administration of nusinersen

Alcyone's ThecaFlex is an implantable medical device under investigation for routine subcutaneous administration of therapeutics to the cerebrospinal fluid (CSF). The first stage of the pivotal IDE PI...

Other symbols: BIIB
5 months ago - PRNewsWire

Ionis Pharmaceuticals, Inc. (IONS) HALOS Study of ION582 in Angelman Syndrome - (Transcript)

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) HALOS Study of ION582 in Angelman Syndrome Conference Call July 22, 2024 8:00 AM ET Company Participants Wade Walke - Senior Vice President of Investor Relat...

5 months ago - Seeking Alpha

Ionis' Rare Development Disorder Drug Candidate 'Could Be Differentiated' From Peer Ultragenyx: Analyst

Ionis Pharmaceuticals Inc IONS released results Monday from the completed multiple ascending dose (MAD) portion of the Phase 1/2 open-label study of ION582 in people with Angelman syndrome (AS).

Other symbols: RARE
5 months ago - Benzinga

Ionis announces positive detailed results from the HALOS Study of ION582 in people with Angelman syndrome

ION582 showed robust and consistent benefit in communication, cognition and motor function in a broad patient population evaluated with a comprehensive set of assessment tools that collect input from ...

5 months ago - PRNewsWire

Ionis to hold second quarter 2024 financial results webcast

Webcast scheduled for Thursday, August 1 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

5 months ago - PRNewsWire

Ionis completes enrollment in pivotal trial evaluating zilganersen in people living with Alexander disease

Zilganersen is the first investigational medicine in clinical development for people with Alexander disease, a rare, life-threatening neurological condition CARLSBAD, Calif. , July 18, 2024 /PRNewswir...

5 months ago - PRNewsWire