Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
75.27
+0.51 (0.68%)
At close: May 1, 2026, 4:00 PM EDT
75.30
+0.03 (0.04%)
After-hours: May 1, 2026, 7:45 PM EDT

Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $12.44 billion. The enterprise value is $13.07 billion.

Market Cap12.44B
Enterprise Value 13.07B

Important Dates

The last earnings date was Wednesday, April 29, 2026, before market open.

Earnings Date Apr 29, 2026
Ex-Dividend Date n/a

Share Statistics

IONS has 165.26 million shares outstanding. The number of shares has increased by 5.71% in one year.

Current Share Class 165.26M
Shares Outstanding 165.26M
Shares Change (YoY) +5.71%
Shares Change (QoQ) +1.77%
Owned by Insiders (%) 0.74%
Owned by Institutions (%) 103.91%
Float 163.98M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 11.76
Forward PS 13.71
PB Ratio 25.41
P/TBV Ratio 25.32
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 12.35
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 4.10, with a Debt / Equity ratio of 5.31.

Current Ratio 4.10
Quick Ratio 2.86
Debt / Equity 5.31
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -3.91

Financial Efficiency

Return on equity (ROE) is -67.62% and return on invested capital (ROIC) is -45.50%.

Return on Equity (ROE) -67.62%
Return on Assets (ROA) -7.03%
Return on Invested Capital (ROIC) -45.50%
Return on Capital Employed (ROCE) -12.89%
Weighted Average Cost of Capital (WACC) 5.73%
Revenue Per Employee $754,772
Profits Per Employee -$233,222
Employee Count1,402
Asset Turnover 0.34
Inventory Turnover 110.49

Taxes

In the past 12 months, IONS has paid $1.89 million in taxes.

Income Tax 1.89M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +145.10% in the last 52 weeks. The beta is 0.38, so IONS's price volatility has been lower than the market average.

Beta (5Y) 0.38
52-Week Price Change +145.10%
50-Day Moving Average 75.31
200-Day Moving Average 69.70
Relative Strength Index (RSI) 52.75
Average Volume (20 Days) 1,748,214

Short Selling Information

The latest short interest is 13.76 million, so 8.33% of the outstanding shares have been sold short.

Short Interest 13.76M
Short Previous Month 14.33M
Short % of Shares Out 8.33%
Short % of Float 8.39%
Short Ratio (days to cover) 6.89

Income Statement

In the last 12 months, IONS had revenue of $1.06 billion and -$326.98 million in losses. Loss per share was -$2.02.

Revenue1.06B
Gross Profit 115.73M
Operating Income -352.25M
Pretax Income -325.09M
Net Income -326.98M
EBITDA -338.65M
EBIT -352.25M
Loss Per Share -$2.02
Full Income Statement

Balance Sheet

The company has $1.98 billion in cash and $2.61 billion in debt, with a net cash position of -$632.58 million or -$3.83 per share.

Cash & Cash Equivalents 1.98B
Total Debt 2.61B
Net Cash -632.58M
Net Cash Per Share -$3.83
Equity (Book Value) 491.41M
Book Value Per Share 2.96
Working Capital 2.22B
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$910.63 million and capital expenditures -$60.63 million, giving a free cash flow of -$971.26 million.

Operating Cash Flow -910.63M
Capital Expenditures -60.63M
Depreciation & Amortization 13.60M
Net Borrowing 502.18M
Free Cash Flow -971.26M
FCF Per Share -$5.88
Full Cash Flow Statement

Margins

Gross margin is 10.94%, with operating and profit margins of -33.29% and -30.90%.

Gross Margin 10.94%
Operating Margin -33.29%
Pretax Margin -30.72%
Profit Margin -30.90%
EBITDA Margin -32.00%
EBIT Margin -33.29%
FCF Margin n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -5.71%
Shareholder Yield -5.71%
Earnings Yield -2.63%
FCF Yield -7.81%
Dividend Details

Analyst Forecast

The average price target for IONS is $94.00, which is 24.88% higher than the current price. The consensus rating is "Strong Buy".

Price Target $94.00
Price Target Difference 24.88%
Analyst Consensus Strong Buy
Analyst Count 22
Revenue Growth Forecast (5Y) 24.90%
EPS Growth Forecast (5Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

IONS has an Altman Z-Score of 1.56 and a Piotroski F-Score of 2. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.56
Piotroski F-Score 2