Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
56.63
+1.21 (2.18%)
Aug 12, 2026, 11:07 AM EDT - Market open

Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $9.41 billion. The enterprise value is $9.50 billion.

Market Cap9.41B
Enterprise Value 9.50B

Important Dates

The last earnings date was Wednesday, July 29, 2026, before market open.

Earnings Date Jul 29, 2026
Ex-Dividend Date n/a

Share Statistics

IONS has 166.18 million shares outstanding. The number of shares has increased by 4.49% in one year.

Current Share Class 166.18M
Shares Outstanding 166.18M
Shares Change (YoY) +4.49%
Shares Change (QoQ) +0.33%
Owned by Insiders (%) 0.76%
Owned by Institutions (%) 104.16%
Float 162.39M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 10.54
Forward PS 9.69
PB Ratio 20.88
P/TBV Ratio 20.94
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 10.64
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 7.89, with a Debt / Equity ratio of 4.98.

Current Ratio 7.89
Quick Ratio 6.85
Debt / Equity 4.98
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -1.14

Financial Efficiency

Return on equity (ROE) is -105.50% and return on invested capital (ROIC) is -72.03%.

Return on Equity (ROE) -105.50%
Return on Assets (ROA) -12.42%
Return on Invested Capital (ROIC) -72.03%
Return on Capital Employed (ROCE) -3.82%
Weighted Average Cost of Capital (WACC) 5.83%
Revenue Per Employee $590,603
Profits Per Employee -$381,874
Employee Count1,480
Asset Turnover 0.29
Inventory Turnover 31.52

Taxes

In the past 12 months, IONS has paid $3.17 million in taxes.

Income Tax 3.17M
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +38.59% in the last 52 weeks. The beta is 0.40, so IONS's price volatility has been lower than the market average.

Beta (5Y) 0.40
52-Week Price Change +38.59%
50-Day Moving Average 66.16
200-Day Moving Average 74.49
Relative Strength Index (RSI) 43.81
Average Volume (20 Days) 2,929,049

Short Selling Information

The latest short interest is 20.04 million, so 12.06% of the outstanding shares have been sold short.

Short Interest 20.04M
Short Previous Month 17.43M
Short % of Shares Out 12.06%
Short % of Float 12.34%
Short Ratio (days to cover) 5.18

Income Statement

In the last 12 months, IONS had revenue of $874.09 million and -$565.17 million in losses. Loss per share was -$3.46.

Revenue874.09M
Gross Profit -60.60M
Operating Income -594.35M
Pretax Income -562.00M
Net Income -565.17M
EBITDA -75.37M
EBIT -102.29M
Loss Per Share -$3.46
Full Income Statement

Balance Sheet

The company has $2.10 billion in cash and $2.19 billion in debt, with a net cash position of -$86.67 million or -$0.52 per share.

Cash & Cash Equivalents 2.10B
Total Debt 2.19B
Net Cash -86.67M
Net Cash Per Share -$0.52
Equity (Book Value) 439.74M
Book Value Per Share 2.65
Working Capital 2.18B
Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$496.43 million and capital expenditures -$64.41 million, giving a free cash flow of -$560.84 million.

Operating Cash Flow -496.43M
Capital Expenditures -64.41M
Depreciation & Amortization 14.87M
Net Borrowing 69.67M
Free Cash Flow -560.84M
FCF Per Share -$3.37
Full Cash Flow Statement

Margins

Gross margin is -6.93%, with operating and profit margins of -68.00% and -64.66%.

Gross Margin -6.93%
Operating Margin -68.00%
Pretax Margin -64.30%
Profit Margin -64.66%
EBITDA Margin -8.62%
EBIT Margin -11.70%
FCF Margin n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -4.49%
Shareholder Yield -4.49%
Earnings Yield -6.14%
FCF Yield -6.09%
Dividend Details

Analyst Forecast

The average price target for IONS is $89.33, which is 57.74% higher than the current price. The consensus rating is "Buy".

Price Target $89.33
Price Target Difference 57.74%
Analyst Consensus Buy
Analyst Count 23
Revenue Growth Forecast (3Y) 28.35%
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date n/a
Split Type n/a
Split Ratio n/a

Scores

IONS has an Altman Z-Score of 1.83 and a Piotroski F-Score of 2. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score 1.83
Piotroski F-Score 2