Ionis Pharmaceuticals Statistics
Total Valuation
IONS has a market cap or net worth of $12.49 billion. The enterprise value is $13.12 billion.
Important Dates
The last earnings date was Wednesday, April 29, 2026, before market open.
| Earnings Date | Apr 29, 2026 |
| Ex-Dividend Date | n/a |
Share Statistics
IONS has 165.26 million shares outstanding. The number of shares has increased by 5.71% in one year.
| Current Share Class | 165.26M |
| Shares Outstanding | 165.26M |
| Shares Change (YoY) | +5.71% |
| Shares Change (QoQ) | +1.77% |
| Owned by Insiders (%) | 0.74% |
| Owned by Institutions (%) | 105.25% |
| Float | 163.98M |
Valuation Ratios
| PE Ratio | n/a |
| Forward PE | n/a |
| PS Ratio | 11.80 |
| Forward PS | 13.62 |
| PB Ratio | 25.51 |
| P/TBV Ratio | 25.41 |
| P/FCF Ratio | n/a |
| P/OCF Ratio | n/a |
| PEG Ratio | n/a |
Financial Ratio HistoryEnterprise Valuation
| EV / Earnings | n/a |
| EV / Sales | 12.40 |
| EV / EBITDA | n/a |
| EV / EBIT | n/a |
| EV / FCF | n/a |
Financial Position
The company has a current ratio of 4.10, with a Debt / Equity ratio of 5.31.
| Current Ratio | 4.10 |
| Quick Ratio | 2.86 |
| Debt / Equity | 5.31 |
| Debt / EBITDA | n/a |
| Debt / FCF | n/a |
| Interest Coverage | -3.91 |
Financial Efficiency
Return on equity (ROE) is -67.62% and return on invested capital (ROIC) is -45.50%.
| Return on Equity (ROE) | -67.62% |
| Return on Assets (ROA) | -7.03% |
| Return on Invested Capital (ROIC) | -45.50% |
| Return on Capital Employed (ROCE) | -12.89% |
| Weighted Average Cost of Capital (WACC) | 5.73% |
| Revenue Per Employee | $754,772 |
| Profits Per Employee | -$233,222 |
| Employee Count | 1,402 |
| Asset Turnover | 0.34 |
| Inventory Turnover | 110.49 |
Taxes
In the past 12 months, IONS has paid $1.89 million in taxes.
| Income Tax | 1.89M |
| Effective Tax Rate | n/a |
Stock Price Statistics
The stock price has increased by +125.55% in the last 52 weeks. The beta is 0.38, so IONS's price volatility has been lower than the market average.
| Beta (5Y) | 0.38 |
| 52-Week Price Change | +125.55% |
| 50-Day Moving Average | 74.25 |
| 200-Day Moving Average | 72.18 |
| Relative Strength Index (RSI) | 52.02 |
| Average Volume (20 Days) | 1,914,300 |
Short Selling Information
The latest short interest is 16.28 million, so 9.85% of the outstanding shares have been sold short.
| Short Interest | 16.28M |
| Short Previous Month | 13.76M |
| Short % of Shares Out | 9.85% |
| Short % of Float | 9.93% |
| Short Ratio (days to cover) | 9.12 |
Income Statement
In the last 12 months, IONS had revenue of $1.06 billion and -$326.98 million in losses. Loss per share was -$2.02.
| Revenue | 1.06B |
| Gross Profit | 115.73M |
| Operating Income | -352.25M |
| Pretax Income | -325.09M |
| Net Income | -326.98M |
| EBITDA | -338.65M |
| EBIT | -352.25M |
| Loss Per Share | -$2.02 |
Full Income StatementBalance Sheet
The company has $1.98 billion in cash and $2.61 billion in debt, with a net cash position of -$632.58 million or -$3.83 per share.
| Cash & Cash Equivalents | 1.98B |
| Total Debt | 2.61B |
| Net Cash | -632.58M |
| Net Cash Per Share | -$3.83 |
| Equity (Book Value) | 491.41M |
| Book Value Per Share | 2.96 |
| Working Capital | 2.22B |
Full Balance SheetCash Flow
In the last 12 months, operating cash flow was -$910.63 million and capital expenditures -$60.63 million, giving a free cash flow of -$971.26 million.
| Operating Cash Flow | -910.63M |
| Capital Expenditures | -60.63M |
| Depreciation & Amortization | 13.60M |
| Net Borrowing | 502.18M |
| Free Cash Flow | -971.26M |
| FCF Per Share | -$5.88 |
Full Cash Flow StatementMargins
Gross margin is 10.94%, with operating and profit margins of -33.29% and -30.90%.
| Gross Margin | 10.94% |
| Operating Margin | -33.29% |
| Pretax Margin | -30.72% |
| Profit Margin | -30.90% |
| EBITDA Margin | -32.00% |
| EBIT Margin | -33.29% |
| FCF Margin | n/a |
Dividends & Yields
IONS does not appear to pay any dividends at this time.
| Dividend Per Share | n/a |
| Dividend Yield | n/a |
| Dividend Growth (YoY) | n/a |
| Years of Dividend Growth | n/a |
| Payout Ratio | n/a |
| Buyback Yield | -5.71% |
| Shareholder Yield | -5.71% |
| Earnings Yield | -2.62% |
| FCF Yield | -7.78% |
Dividend DetailsAnalyst Forecast
The average price target for IONS is $100.92, which is 33.56% higher than the current price. The consensus rating is "Buy".
| Price Target | $100.92 |
| Price Target Difference | 33.56% |
| Analyst Consensus | Buy |
| Analyst Count | 26 |
| Revenue Growth Forecast (5Y) | 24.90% |
| EPS Growth Forecast (5Y) | n/a |
Stock ForecastsFair Value
There are several formulas that can be used to estimate the intrinsic value of a stock.
| Lynch Fair Value | n/a |
| Lynch Upside | n/a |
| Graham Number | n/a |
| Graham Upside | n/a |
Stock Splits
This stock does not have any record of stock splits.
| Last Split Date | n/a |
| Split Type | n/a |
| Split Ratio | n/a |
Scores
IONS has an Altman Z-Score of 1.56 and a Piotroski F-Score of 2. A Z-score under 3 suggests an increased risk of bankruptcy.
| Altman Z-Score | 1.56 |
| Piotroski F-Score | 2 |
