Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · Real-Time Price · USD

75.27

+0.51 (0.68%)

At close: May 1, 2026, 4:00 PM EDT

75.30

+0.03 (0.04%)

After-hours: May 1, 2026, 7:45 PM EDT

Ionis Pharmaceuticals Income Statement

Financials in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	TTM	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar '26 Mar 31, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Revenue	1,058	943.71	705.14	787.65	587.37	810.46
Revenue Growth (YoY)	47.53%	33.83%	-10.47%	34.10%	-27.53%	11.13%
Cost of Revenue	17.43	15.91	11.22	9.13	14.12	10.84
Gross Profit	1,041	927.8	693.92	778.51	573.25	799.61
Selling, General & Admin	467.98	393.87	267.47	232.62	150.3	186.35
Research & Development	925.03	915.62	901.53	899.63	833.15	643.45
Total Operating Expenses	1,393	1,309	1,169	1,132	983.44	829.8
Operating Income	-352.25	-381.68	-475.08	-353.73	-410.19	-30.19
Interest Income	98.58	97.77	107.02	89.04	25.33	10.04
Interest Expense	-90.11	-90.54	-90.45	-81.46	-8.12	-9.35
Other Non-Operating Income (Expense)	39.19	-5.14	-1.56	12.18	135	0.34
Total Non-Operating Income (Expense)	47.66	2.08	15.01	19.77	152.21	1.04
Pretax Income	-325.09	-379.6	-460.07	-333.97	-257.99	-29.15
Provision for Income Taxes	1.89	1.79	-6.17	32.32	11.74	-0.55
Net Income	-326.98	-381.39	-453.9	-366.29	-269.72	-28.6
Net Income to Common	-326.98	-381.39	-453.9	-366.29	-269.72	-28.6
Shares Outstanding (Basic)	161	160	150	143	142	141
Shares Outstanding (Diluted)	167	160	150	143	142	141
Shares Change (YoY)	9.44%	7.02%	4.42%	0.95%	0.59%	1.01%
EPS (Basic)	-1.99	-2.38	-3.04	-2.56	-1.90	-0.20
EPS (Diluted)	-2.07	-2.38	-3.04	-2.56	-1.90	-0.20
Shares Outstanding	165.9	163.31	157.91	144.34	142.06	141.21
Free Cash Flow	-971.26	-320.03	-546.23	-331.32	-290.09	18.84
Free Cash Flow Growth	-	-	-	-	-	2340.93%
Free Cash Flow Per Share	-5.81	-2.00	-3.65	-2.31	-2.05	0.13
Gross Margin	98.35%	98.31%	98.41%	98.84%	97.60%	98.66%
Operating Margin	-33.29%	-40.45%	-67.37%	-44.91%	-69.84%	-3.72%
Profit Margin	-30.90%	-40.41%	-64.37%	-46.50%	-45.92%	-3.53%
FCF Margin	-91.78%	-33.91%	-77.46%	-42.06%	-49.39%	2.33%
EBITDA	-327.51	-358.99	-453.09	-331.23	-388.09	-10.63
EBITDA Margin	-30.95%	-38.04%	-64.26%	-42.05%	-66.07%	-1.31%
EBIT	-352.25	-381.68	-475.08	-353.73	-410.19	-30.19
EBIT Margin	-33.29%	-40.45%	-67.37%	-44.91%	-69.84%	-3.72%
Effective Tax Rate	-0.58%	-0.47%	1.34%	-9.68%	-4.55%	1.89%

Updated Apr 29, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q