Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
43.03
+0.05 (0.12%)
At close: Aug 1, 2025, 4:00 PM
42.58
-0.45 (-1.05%)
After-hours: Aug 1, 2025, 7:23 PM EDT

Company Description

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States.

The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA).

It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSEDI for the treatment of ATTRv-PN in adults; and WAYLIVRA for treatment for FCS and familial partial lipodystrophy.

It also develops products under Phase 3 clinical trials, such as Olezarsen for patients with hypertriglyceridemia (SHTG) and cardiovascular disease (CVD); Donidalorsen for patients with hereditary angioedema; and Zilganerse, a potential treatment for people with genetically confirmed Alexander disease, as well as ION582 that has completed Phase 2 clinical trial for the potential treatment of AS, a rare genetic neurological disease.

In addition, the company develops Eplontersen to degrade mutant and wild-type TTR mRNA through binding to the TTR mRNA; Pelacarsen to inhibit the production of apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a); Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus; Sefaxersen to reduce the production of complement factor B and lower activation of the alternative complement pathway; and Ulefnersen to reduce the production of the fused in sarcoma, as well as other mid-stage pipeline investigational medicines.

It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with GSK, AstraZeneca, Novartis, and Roche, as well as with Metagenomi.

The company was incorporated in 1989 and is headquartered in Carlsbad, California.

Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals logo
CountryUnited States
Founded1989
IPO DateMay 17, 1991
IndustryBiotechnology
SectorHealthcare
Employees1,069
CEOBrett Monia

Contact Details

Address:
2855 Gazelle Court
Carlsbad, California 92010
United States
Phone760 931 9200
Websiteionis.com

Stock Details

Ticker SymbolIONS
ExchangeNASDAQ
Stock TypeCommon Stock
Fiscal YearJanuary - December
Reporting CurrencyUSD
CIK Code0000874015
CUSIP Number462222100
ISIN NumberUS4622221004
Employer ID33-0336973
SIC Code2834

Key Executives

NamePosition
Dr. Brett P. Monia Ph.D.Founder, Chief Executive Officer and Director
Elizabeth L. Hougen M.A., M.B.A., M.S.Executive Vice President of Finance and Chief Financial Officer
Patrick R. O'Neil Esq.Executive Vice President, Chief Legal Officer, General Counsel and Corporate Secretary
Dr. Richard S. Geary Ph.D.Executive Vice President and Chief Development Officer
Kyle JenneExecutive Vice President and Chief Global Product Strategy Officer
Darren GonzalesChief Accounting Officer and Senior Vice President
Dr. C. Frank Bennett BSc, Ph.D.Executive Vice President and Chief Scientific Officer
D. Wade Walke Ph.D.Senior Vice President of Investor Relations
Tracy Berns J.D.Senior Vice President and Chief Compliance and Quality Assurance Officer
Hayley SofferVice President of Corporate Communications

Latest SEC Filings

DateTypeTitle
Jul 30, 2025144Filing
Jul 30, 2025S-8Securities to be offered to employees in employee benefit plans
Jul 30, 202510-QQuarterly Report
Jul 30, 20258-KCurrent Report
Jun 12, 20258-KCurrent Report
Jun 10, 20258-KCurrent Report
May 19, 20258-KCurrent Report
Apr 30, 202510-QQuarterly Report
Apr 30, 20258-KCurrent Report
Apr 25, 2025ARSFiling