Ionis Pharmaceuticals, Inc. (IONS)

Ionis Pharmaceuticals Stock Forecast

Stock Price Forecast

The 22 analysts that cover Ionis Pharmaceuticals stock have a consensus rating of "Strong Buy" and an average price target of $82.82, which forecasts a 3.62% increase in the stock price over the next year. The lowest target is $39 and the highest is $110.

Price Target: $82.82 (+3.62%)

Analyst Consensus: Strong Buy

Target	Low	Average	Median	High
Price	$39	$82.82	$90	$110
Change	-51.21%	+3.62%	+12.60%	+37.62%

Analyst Ratings

The average analyst rating for Ionis Pharmaceuticals stock is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating	Jul '25	Aug '25	Sep '25	Oct '25	Nov '25	Dec '25
Strong Buy	5	6	8	9	9	9
Buy	5	5	6	8	8	9
Hold	3	4	4	4	4	4
Sell	0	0	0	0	0	0
Strong Sell	1	0	0	0	0	0
Total	14	15	18	21	21	22

Latest Forecasts

Analyst	Firm	Rating	Rating	Action	Price Target	Upside	Date
Luca Issi RBC Capital	RBC Capital	Buy Maintains $82 → $95	Buy	Maintains	$82 → $95	+18.85%	Dec 17, 2025
Mani Foroohar Leerink Partners	Leerink Partners	Buy Maintains $85 → $100	Buy	Maintains	$85 → $100	+25.11%	Dec 15, 2025
Jason Gerberry B of A Securities	B of A Securities	Strong Buy Maintains $86 → $97	Strong Buy	Maintains	$86 → $97	+21.36%	Dec 9, 2025
Mitchell S. Kapoor HC Wainwright & Co.	HC Wainwright & Co.	Strong Buy Maintains $100 → $110	Strong Buy	Maintains	$100 → $110	+37.62%	Nov 10, 2025
Allison Bratzel Piper Sandler	Piper Sandler	Buy Maintains $70 → $77	Buy	Maintains	$70 → $77	-3.67%	Nov 4, 2025

More Analyst Ratings

Financial Forecast

Revenue This Year

914.68M

Increased by 29.72%

from 705.14M

Revenue Next Year

923.51M

Increased by 0.97%

from 914.68M

EPS This Year

-2.31

from -3.04

EPS Next Year

-3.12

from -2.31

Fiscal Year	FY 2020	FY 2021	FY 2022	FY 2023	FY 2024	FY 2025	FY 2026
Period Ending	Dec 31, 2020	Dec 31, 2021	Dec 31, 2022	Dec 31, 2023	Dec 31, 2024	Dec 31, 2025	Dec 31, 2026
Revenue	729.26M	810.46M	587.37M	787.65M	705.14M	914.68M	923.51M
Revenue Growth	-35.04%	11.13%	-27.53%	34.10%	-10.48%	29.72%	0.97%
EPS	-3.18	-0.20	-1.90	-2.56	-3.04	-2.31	-3.12
EPS Growth	-	-	-	-	-	-	-
Forward PE	-	-	-	-	-	-	-
No. Analysts	-	-	-	-	-	25	25

Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue	2025	2026	2027	2028	2029	2030
High	968.8M	1.2B
Avg	914.7M	923.5M
Low	847.7M	673.1M

Revenue Growth

Revenue Growth	2025	2026	2027	2028	2029	2030
High	37.4%	30.3%
Avg	29.7%	1.0%
Low	20.2%	-26.4%

EPS Forecast

EPS	2025	2026	2027	2028	2029	2030
High	-1.94	-1.59
Avg	-2.31	-3.12
Low	-2.42	-4.26

EPS Growth

EPS Growth	2025	2026	2027	2028	2029	2030
High	-	-
Avg	-	-
Low	-	-

Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.