Karyopharm Therapeutics Inc. (KPTI)

NASDAQ: KPTI · Real-Time Price · USD
0.598
-0.012 (-1.90%)
At close: Feb 21, 2025, 4:00 PM
0.609
+0.011 (1.77%)
After-hours: Feb 21, 2025, 5:20 PM EST
-1.90%
Market Cap 75.54M
Revenue (ttm) 145.24M
Net Income (ttm) -76.42M
Shares Out 126.24M
EPS (ttm) -0.93
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 1,053,673
Open 0.602
Previous Close 0.610
Day's Range 0.590 - 0.625
52-Week Range 0.530 - 1.700
Beta 0.06
Analysts Strong Buy
Price Target 5.00 (+735.56%)
Earnings Date Feb 19, 2025

About KPTI

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myelom... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 6, 2013
Employees 325
Stock Exchange NASDAQ
Ticker Symbol KPTI
Full Company Profile

Financial Performance

In 2024, Karyopharm Therapeutics's revenue was $145.24 million, a decrease of -0.55% compared to the previous year's $146.03 million. Losses were -$76.42 million, -46.60% less than in 2023.

Financial Statements

Analyst Forecast

According to 4 analysts, the average rating for KPTI stock is "Strong Buy." The 12-month stock price forecast is $5.0, which is an increase of 735.56% from the latest price.

Price Target
$5.0
(735.56% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Karyopharm Therapeutics Inc. (KPTI) Q4 2024 Earnings Call Transcript

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Q4 2024 Earnings Call February 19, 2025 8:00 AM ET Company Participants Brendan Strong - SVP, IR Richard Paulson - President and CEO Reshma Rangwala - CMO &...

3 days ago - Seeking Alpha

Karyopharm Reports Fourth Quarter and Full Year 2024 Financial Results, Announces Update to Phase 3 XPORT-EC-042 Trial and Highlights Recent Company Progress

– Total Revenue of $145 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $113 Million for Full Year 2024 – – Top-Line Data Readout from Phase 3 SENTRY Trial Evaluating Selinexor in Combinat...

3 days ago - PRNewsWire

Antengene Announces XPOVIO® Approved for Public Health Insurance Coverage in Taiwan Market, Benefiting More Patients with R/R MM in the Region

XPOVIO® is the first XPO1 inhibitor approved in Taiwan for the treatment of adult patients with relapsed/refractory multiple myeloma (R/R MM). After the mainland of China, South Korea, Australia and S...

9 days ago - PRNewsWire

Karyopharm to Report Fourth Quarter and Full Year 2024 Financial Results on February 19, 2025

-- Conference Call Scheduled for Wednesday, February 19, 2025, at 8:00 a.m. ET -- NEWTON, Mass.

10 days ago - PRNewsWire

Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NEWTON, Mass. , Feb. 3, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company ...

19 days ago - PRNewsWire

Karyopharm Announces Preliminary Unaudited 2024 Revenue and 2025 Objectives

– Opportunity to Define a New Myelofibrosis Treatment Paradigm with Top-Line Data Readout from Phase 3 SENTRY Trial Evaluating Selinexor in Combination with Ruxolitinib in Patients with JAKi-Naïve Mye...

5 weeks ago - PRNewsWire

Karyopharm Announces the Appointment of Lori Macomber as Chief Financial Officer

NEWTON, Mass. , Jan. 2, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced the appointment o...

7 weeks ago - PRNewsWire

Karyopharm Announces the Appointment of Brendan Strong as Senior Vice President of Investor Relations and Corporate Communications

NEWTON, Mass. , Dec. 9, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced the appointment o...

2 months ago - PRNewsWire

Karyopharm Therapeutics Provides Endometrial Cancer Program Update

NEWTON, Mass. , Dec. 3, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it is in dis...

2 months ago - PRNewsWire

Karyopharm to Participate at the Piper Sandler 36th Annual Healthcare Conference

NEWTON, Mass. , Nov. 25, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company...

3 months ago - PRNewsWire

Karyopharm Therapeutics Announces the Appointment of Chief Accounting Officer

NEWTON, Mass. , Nov. 20, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that Kristin Aba...

3 months ago - PRNewsWire

Karyopharm to Present Selinexor Data at the 66th American Society of Hematology Annual Meeting and Exposition

NEWTON, Mass. , Nov. 18, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced abstracts detail...

3 months ago - PRNewsWire

Karyopharm Therapeutics Inc. (KPTI) Q3 2024 Earnings Call Transcript

Karyopharm Therapeutics Inc. (NASDAQ:KPTI) Q3 2024 Earnings Conference Call November 5, 2024 8:00 AM ET Company Participants Elhan Webb - Senior Vice President, Investor Relations Richard Paulson - P...

3 months ago - Seeking Alpha

Antengene to Present Results from Two Late-Stage Studies of Selinexor Signaling Potential Clinical Breakthrough at ASH 2024

SHANGHAI and HONG KONG , Nov. 5, 2024 /PRNewswire/ -- Antengene Corporation Limited ("Antengene", SEHK: 6996.HK), a leading innovative, commercial-stage global biopharmaceutical company dedicated to d...

3 months ago - PRNewsWire

Karyopharm Reports Third Quarter 2024 Financial Results and Highlights Recent Company Progress

– Achieves Third Quarter 2024 Total Revenue of $38.8 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $29.5 Million; Continued Regulatory and Reimbursement Approvals Globally – – Following ...

3 months ago - PRNewsWire

Karyopharm to Report Third Quarter 2024 Financial Results on November 5, 2024

-- Conference Call Scheduled for Tuesday, November 5, 2024, at 8:00 a.m. ET -- NEWTON, Mass.

4 months ago - PRNewsWire

Karyopharm Announces Favorable Change in Co-Primary Endpoint for Pivotal Phase 3 SENTRY Trial in Myelofibrosis

Co-primary Endpoint Changed to Absolute Total Symptom Score (Abs-TSS) from Total Symptom Score Improvement of ≥ 50% (TSS50) Following Alignment with the FDA Spleen Volume Response Rate ≥ 35% (SVR35) R...

4 months ago - PRNewsWire

Karyopharm to Host Investor Event with Leading Myelofibrosis KOLs and Provide a Favorable Study Design Update on October 31, 2024

Company to host a conference call tomorrow at 8:00 a.m. ET NEWTON, Mass.

4 months ago - PRNewsWire

Antengene Announces XPOVIO® (selinexor) Approved for Its Third Indication in South Korea, Bringing Fresh Hope to Patients with MM in the Country

This approval for XPOVIO® for the treatment of patients with multiple myeloma (MM) marks the third approved indication of the drug in South Korea. To date, XPOVIO® has already been included in nationa...

4 months ago - PRNewsWire

Antengene Announces XPOVIO® (selinexor) Approved for Commercialization in Thailand

XPOVIO® is the first and only approved XPO1 inhibitor in Thailand. XPOVIO® has been approved for multiple indications in nine markets across the APAC region.

5 months ago - PRNewsWire

Karyopharm to Participate at Upcoming Investor Conferences

NEWTON, Mass. , Sept. 3, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies , today announced that the Compan...

6 months ago - PRNewsWire

Karyopharm Reports Second Quarter 2024 Financial Results and Highlights Recent Company Progress

– Achieves Second Quarter 2024 Total Revenue of $42.8 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $28.0 Million; Positive Momentum ex-US with Continued Regulatory and Reimbursement App...

7 months ago - PRNewsWire

Antengene Announces XPOVIO® (selinexor) Approved for Commercialization in Malaysia

XPOVIO® is the first and only approved XPO1 inhibitor in Malaysia. XPOVIO® has been approved for multiple indications in eight markets across the APAC region.

7 months ago - PRNewsWire

Karyopharm to Report Second Quarter 2024 Financial Results on August 6, 2024

-- Conference Call Scheduled for Tuesday, August 6, 2024, at 8:00 a.m. ET -- NEWTON, Mass.

7 months ago - PRNewsWire

XPOVIO® (selinexor) Approved for New Indication in DLBCL in China, Bringing a New Treatment Option to Patients in the Country

- Following its initial approval for the treatment of relapsed/refractory multiple myeloma (R/R MM), XPOVIO® has now received approval as a monotherapy for the treatment of adult patients with relapse...

8 months ago - PRNewsWire