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Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTI · Real-Time Price · USD
0.4632
+0.0388 (9.14%)
Oct 22, 2026, 11:06 AM EDT - Market open

Karyopharm Therapeutics Ratios and Metrics

Millions USD. Fiscal year is Jan - Dec.

Total Valuation

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Market Capitalization
111358599385486
Market Cap Growth
-79.56%57.91%-13.86%-74.26%-20.76%-57.36%
Enterprise Value
274359220201549595
Last Close Price
0.427.3610.1412.9751.0096.45

Price Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
PS Ratio
0.070.920.590.682.452.32
PB Ratio
--0.46-0.46-0.73-23.11-6.10

EV Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
EV/Sales Ratio
1.862.461.511.383.502.84

Financial Efficiency

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Debt / Equity Ratio
-0.99-1.04-1.44-2.27-18.72-3.94
Net Debt / Equity Ratio
-0.80-0.83-0.86-0.87-2.03-1.07
Net Debt / EBITDA Ratio
-3.20-2.68-1.34-0.91-0.24-0.87
Net Debt / FCF Ratio
-4.03-3.21-1.25-1.27-0.23-0.79
Asset Turnover
1.361.070.720.490.470.68
Inventory Turnover
0.311.361.541.361.251.01
Quick Ratio
0.710.981.513.165.053.43
Current Ratio
0.791.121.703.375.313.74
Return on Assets (ROA)
-47.61%-41.56%-36.88%-27.05%-26.79%-19.86%
Return on Capital Employed (ROCE)
359.40%-554.60%-165.50%-75.80%-48.70%-42.40%

Yields

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Oct '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Earnings Yield
-2500.33%-145.47%-89.55%-144.44%-42.94%-25.55%
FCF Yield
-678.86%-55.93%-149.55%-93.59%-38.88%-22.09%
Buyback Yield / Dilution
-129.56%-29.33%-11.02%-39.54%-8.85%-4.41%
SEC Filings: 10-K · 10-Q