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Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTI · Real-Time Price · USD
1.720
-0.070 (-3.91%)
At close: Sep 8, 2026, 4:00 PM EDT
1.750
-0.040 (-2.23%)
After-hours: Sep 8, 2026, 7:30 PM EDT

Karyopharm Therapeutics Ratios and Metrics

Millions USD. Fiscal year is Jan - Dec.

Total Valuation

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Sep '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Market Capitalization
391358599385486
Market Cap Growth
-36.46%57.91%-13.86%-74.26%-20.76%-57.36%
Enterprise Value
302359220201549595
Last Close Price
1.727.3610.1412.9751.0096.45

Price Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Sep '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
PS Ratio
0.270.920.590.682.452.32
PB Ratio
--0.46-0.46-0.73-23.11-6.10

EV Ratios

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Sep '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
EV/Sales Ratio
2.062.461.511.383.502.84

Financial Efficiency

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Sep '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Debt / Equity Ratio
-0.99-1.04-1.44-2.27-18.72-3.94
Net Debt / Equity Ratio
-0.80-0.83-0.86-0.87-2.03-1.07
Net Debt / EBITDA Ratio
-3.20-2.68-1.34-0.91-0.24-0.87
Net Debt / FCF Ratio
-4.03-3.21-1.25-1.27-0.23-0.79
Asset Turnover
1.361.070.720.490.470.68
Inventory Turnover
28.2629.9838.3539.5536.951.01
Quick Ratio
0.710.981.513.165.053.43
Current Ratio
0.791.121.703.375.313.74
Return on Assets (ROA)
-47.61%-41.56%-36.88%-27.05%-26.79%-19.86%
Return on Capital Employed (ROCE)
359.40%-554.60%-165.50%-75.80%-48.70%-42.40%

Yields

Fiscal Year
CurrentFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Sep '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Earnings Yield
-576.08%-145.47%-89.55%-144.44%-42.94%-25.55%
FCF Yield
-167.50%-55.93%-149.55%-93.59%-38.88%-22.09%
Buyback Yield / Dilution
-129.56%-29.33%-11.02%-39.54%-8.85%-4.41%
SEC Filings: 10-K · 10-Q