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Prime Medicine, Inc. (PRME)
NASDAQ: PRME · Real-Time Price · USD
3.130
-0.190 (-5.72%)
At close: Oct 14, 2026, 4:00 PM EDT
3.129
-0.001 (-0.02%)
After-hours: Oct 14, 2026, 7:57 PM EDT

Prime Medicine Cash Flow Statement

Millions USD. Fiscal year is Jan - Dec.

Operating Activities

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Net Income
-187.89-201.14-195.88-198.13-121.82-165.37
Depreciation & Amortization
7.47.326.134.652.220.57
Loss (Gain) From Sale of Assets
---0.030.01-
Asset Writedown & Restructuring Costs
-----12.02
Loss (Gain) From Sale of Investments
-4.1-2.37-2.61-1.037.881.11
Stock-Based Compensation
26.7729.2726.0713.916.461.75
Other Operating Activities
10.659.712.3612.518.8384.67
Change in Accounts Payable
-0.511-5.269.142.461.19
Change in Unearned Revenue
-3.91-4.3670.31---
Change in Other Net Operating Assets
-4.46-1.98-33.98-6.49-37.8629.99
Operating Cash Flow
-156.05-162.56-122.87-165.41-131.83-34.08
Operating Cash Flow Growth
------

Investing Activities

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Capital Expenditures
-0.8-4.53-7.29-8.72-16.1-4.15
Investment in Securities
4.43-104.2374.7527.61-30.34-68.98
Other Investing Activities
--1-0.17-0.67-0.5
Investing Cash Flow
3.63-108.7668.4618.71-47.1-73.63

Financing Activities

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Issuance of Common Stock
140.07139.51171.080.66185.54-
Other Financing Activities
61224.8--4.04-1.09
Financing Cash Flow
146.07151.51195.880.66181.49269.28

Net Cash Flow

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Net Cash Flow
-6.35-119.82141.47-146.052.57161.57

Free Cash Flow

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Free Cash Flow
-156.85-167.1-130.16-174.14-147.92-38.23
Free Cash Flow Growth
------
Free Cash Flow Margin
-3850.92%-3607.40%-4363.36%---
Free Cash Flow Per Share
-0.91-1.12-1.10-1.91-4.37-2.95
Levered Free Cash Flow
-75.78-85.37-114.57-96.21-117.62-6.8
Unlevered Free Cash Flow
-75.78-85.37-114.57-96.21-117.62-6.8

Additional Metrics

Fiscal Year
TTMFY 2025FY 2024FY 2023FY 2022FY 2021
Period Ending
Jun '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21
Change in Working Capital
-8.88-5.3431.082.65-35.431.18
SEC Filings: 10-K · 10-Q