Prime Medicine Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar '26 Mar 18, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Cap	637	626	383	863	1,806	-
Market Cap Growth	126.41%	63.55%	-55.61%	-52.23%	-	-
Enterprise Value	576.1	556.99	229.73	745.45	1,529	0
Last Close Price	3.53	3.47	2.92	8.86	18.58	-
PE Ratio	-	-2.57	-1.77	-4.06	-4.43	-
PS Ratio	137.60	135.23	128.39	-	-	-
PB Ratio	5.17	5.18	2.50	6.48	5.71	-
P/TBV Ratio	4.35	4.27	2.26	6.06	1.99	-
P/FCF Ratio	-	-3.75	-2.94	-4.95	-12.21	-
P/OCF Ratio	-	-3.85	-3.12	-5.22	-13.70	-
EV/Sales Ratio	124.37	120.25	77.01	-	-	-
EV/EBITDA Ratio	-	-2.77	-1.17	-3.72	-13.38	-
EV/EBIT Ratio	-	-2.67	-1.13	-3.64	-13.12	-
EV/FCF Ratio	-	-3.33	-1.76	-4.28	-10.34	-
Debt / Equity Ratio	0.90	0.90	0.24	0.03	0.05	0.01
Debt / EBITDA Ratio	-0.58	-0.58	-0.21	-0.07	-0.25	-0.12
Debt / FCF Ratio	-0.70	-0.70	-0.31	-0.08	-0.19	-0.27
Net Debt / Equity Ratio	-0.51	-0.51	-0.98	-0.81	-0.84	1.66
Net Debt / EBITDA Ratio	0.31	0.31	0.76	0.54	2.32	3.09
Net Debt / FCF Ratio	0.37	0.37	1.15	0.62	1.79	6.78
Asset Turnover	0.01	0.01	0.01	0	0	0
Quick Ratio	4.74	4.74	5.02	2.16	11.00	4.65
Current Ratio	4.84	4.84	5.58	2.53	11.10	4.67
Return on Equity (ROE)	-76.26%	-146.81%	-136.88%	-88.44%	-44.52%	-121.13%
Return on Assets (ROA)	-65.08%	-65.08%	-82.41%	-74.01%	-35.47%	-47.23%
Return on Invested Capital (ROIC)	-186.55%	-186.55%	-342.15%	-456.18%	-522.18%	2803.81%
Return on Capital Employed (ROCE)	-73.77%	-73.77%	-102.00%	-86.96%	-40.36%	-60.51%
Earnings Yield	-31.56%	-38.90%	-56.51%	-24.60%	-22.55%	-
FCF Yield	-26.22%	-26.68%	-33.98%	-20.18%	-8.19%	-
Buyback Yield / Dilution	-22.27%	-22.27%	-49.58%	-0.08%	-10.27%	-

Updated Dec 31, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.

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