Prime Medicine Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Feb '26 Feb 26, 2026	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020
Market Capitalization	775	373	817	1,609	-	-
Market Cap Growth	151.12%	-54.41%	-49.22%	-	-	-
Enterprise Value	692	238	669	1,890	-	-
Last Close Price	4.13	2.92	8.86	18.58	-	-
PS Ratio	131.66	124.90	-	-	-	-
PB Ratio	4.51	2.43	6.14	5.09	-	-
P/TBV Ratio	4.86	2.43	6.14	5.09	-	-
EV/Sales Ratio	115.74	79.89	-	-	-	-
Debt / Equity Ratio	0.73	0.27	0.10	0.09	0.04	0.52
Net Debt / Equity Ratio	-0.59	-0.98	-0.81	-0.84	-1.08	-1.07
Net Debt / EBITDA Ratio	0.48	0.76	0.58	2.32	3.09	40.28
Net Debt / FCF Ratio	0.83	1.15	0.62	1.79	6.78	5.79
Asset Turnover	0.02	0.01	-	-	-	0.16
Quick Ratio	6.09	5.02	2.16	11.00	4.65	2.74
Current Ratio	6.61	5.58	2.53	11.10	4.67	2.75
Return on Equity (ROE)	-112.34%	-136.88%	-88.19%	-43.83%	-121.13%	-19.56%
Return on Assets (ROA)	-35.52%	-51.51%	-43.15%	-22.00%	-29.61%	-1.84%
Return on Capital Employed (ROCE)	-58.30%	-78.00%	-139.20%	-34.90%	-34.60%	-2.60%
Earnings Yield	-25.08%	-52.58%	-24.25%	-7.57%	-	-
FCF Yield	-14.63%	-34.94%	-21.31%	-9.19%	-	-
Buyback Yield / Dilution	-25.86%	-30.37%	-168.41%	-161.23%	-391.47%	-77.53%

Updated Nov 7, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q